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31:39EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年8月20日播客 · 2 人对谈The Skull Is Already the Vat: Max Hodak on Restoring Sight主持 Sarah Guo, Elad GilPatients blinded by macular degeneration put on laser-projector glasses, read books, and fill in Sudoku — because a chip under the retina is sending vision back into the brain.Brain-Computer InterfacesAI in healthcareNeuroscience & AI+3
48:14EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年11月13日播客 · 2 人对谈A New Drug Burns $2 Billion and 10 Years. Benchling's CEO Wants AI to Cut That to Three主持 Sarah Guo, Elad GilMost medicines fail in years seven to ten, after hundreds of millions have already gone into the clinic—and Sajith Wickramasekara thinks sending things to space may already be easier.智能体AI for scienceAI in healthcare+3
44:49EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年9月5日播客 · 2 人对谈How OpenEvidence Became the Clinical OS for 40% of U.S. Doctors主持 Sarah Guo, Elad GilFounder Daniel Nadler tells No Priors how a free search tool for physicians, not an answer engine for patients, took high-stakes clinical knowledge in 18 months.RAG 与知识库检索增强生成Search & retrieval+3
49:27EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年7月3日播客 · 2 人对谈From 0.1% to 20%: Chai-2 Turns Antibody Design Into Prompt Engineering主持 Sarah Guo, Elad GilChai Discovery co-founders Joshua Meier and Jack Dent tell Sarah Guo how a generative model now designs antibodies that bind on the first 24-well plate.AI for scienceDrug DiscoveryAI startups & small teams+3
38:43EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年3月27日播客 · 2 人对谈Two in Five Doctors Want Out. An On-Call Cardiologist Built the Note That Lets Them Stay主持 Sarah Guo, Elad GilAbridge CEO Shiv Rao on treating the doctor-patient conversation as healthcare's source of truth, and why the company ran straight at the hardest health systems.企业与战略AI in healthcare语音 AI+3
42:18EN
No Priors: AI, Machine Learning, Tech, & Startups· 2023年5月18日播客 · 2 人对谈Ten Percent of Search Is Health — and the Doctor Is Googling Too主持 Sarah Guo, Elad GilGoogle researcher Karan Singhal on Med-PaLM 2, the real bar for medical language models, and why medicine is a harder alignment lab than chatbots.模型与训练AI in healthcare安全与治理+3
46:57EN
No Priors: AI, Machine Learning, Tech, & Startups· 2023年3月2日播客 · 2 人对谈95% of Drug Programs Fail. Daphne Koller Is Betting Machine Learning on the First Decision主持 Sarah Guo, Elad GilA new medicine still takes more than a decade and well over a billion dollars — and Insitro's founder argues the expensive failures start with the wrong target, indication, or patient.企业与战略AI in healthcareAI for science+3
50:12EN
No Priors: AI, Machine Learning, Tech, & Startups· 2023年2月20日播客 · 2 人对谈The Drone Is Only 15 Percent of the Problem主持 Sarah Guo, Elad GilZipline CEO Keller Rinaudo Cliffton on why blood delivery in Rwanda, not a cooler airplane, built the world's largest commercial autonomous system.企业与战略Company BuildingAutonomous Systems+3
2:43:51EN → 简体中文
Lex Fridman· 2022年6月25日播客 · 2 人对谈两根管子,相距几毫米:Jonathan Reisman 谈人体的诚实设计嘉宾 Jonathan Reisman · 主持 Lex Fridman这位急诊医生、《看不见的身体》(The Unseen Body)的作者,带 Lex Fridman 从喉咙一路走到北极。他认为,人体解剖大多精妙,有时只差一点点,而且始终是一部写在伤疤上的故事。EvolutionPhilosophyScience Communication+3
3:21:29EN → 简体中文
Lex Fridman· 2022年4月7日播客 · 2 人对谈心智一出问题,才看得出它原本是做什么用的嘉宾 Karl Deisseroth · 主持 Lex Fridman斯坦福大学精神科医生 Karl Deisseroth 与 Lex Fridman 谈抑郁症、精神分裂症和光遗传学(optogenetics),以及为什么不必先有一套“万物理论”,也能先治好眼前的一种症状。Mental HealthNeuroscienceNeuroscience & AI+3
1:41:34EN
Lex Fridman· 2021年6月6日播客 · 2 人对谈Aging Is a Scratched Disc. David Sinclair Thinks the Body Kept a Backup嘉宾 David Sinclair · 主持 Lex FridmanThe Harvard geneticist tells Lex Fridman why aging is information loss, how three genes gave a blind mouse its sight back, and why skipping meals may beat the perfect diet.Computational BiologyAI in healthcarePublic Health+1
2:31:30EN → 简体中文
Lex Fridman· 2021年5月24日播客 · 2 人对谈大脑是社会里最后一个没有被工程化的系统嘉宾 Bryan Johnson · 主持 Lex FridmanBryan Johnson 在 Lex Fridman 面前演示了 Kernel Flow,然后主张:认知是社会最大的未被测量的输入,心理健康、饮食和下一波脑机接口,都应当靠数字说话,别靠感觉。Brain-Computer InterfacesNeuroscience & AIPhilosophy of Mind+3
2:39:45EN
Lex Fridman· 2020年10月25日播客 · 2 人对谈The obesity gene was never the obesity gene嘉宾 Manolis Kellis · 主持 Lex FridmanManolis Kellis tells Lex Fridman how one nucleotide a million bases from FTO rewrote obesity biology, and why human genetics is now driving the study of disease.Computational BiologyAI in healthcareAI for science+2
1:02:14EN
Lex Fridman· 2020年6月30日播客 · 2 人对谈The 28-year wait: Robert Langer on rejection, polymers, and a thousand students嘉宾 Robert Langer · 主持 Lex FridmanThe MIT bioengineer talks with Lex Fridman about drug delivery, tissue engineering, patents, and the long path from a Folkman hypothesis to Avastin.企业与战略AI in healthcareAI for science+3
1:12:03EN
Lex Fridman· 2020年5月5日播客 · 2 人对谈Mice Don't Get Alzheimer's: Daphne Koller on Disease in a Dish嘉宾 Daphne Koller · 主持 Lex FridmanThe Coursera co-founder and insitro CEO on why most diseases are not one disease, how to turn cells into data, and why overconfident neural nets can kill.AI in healthcareComputational BiologyAI for science+3
36:10EN
Lex Fridman· 2019年11月12日播客 · 2 人对谈So You're Saying There's a Chance: Musk on Neuralink, AI, and a Pale Blue Dot嘉宾 Elon Musk · 主持 Lex FridmanLex Fridman and Elon Musk move from consciousness and an AI referee to the engineering of a brain implant, Tesla Autopilot, and Carl Sagan's lonely speck.安全安全与治理Existential Risk+3
1:17:29EN
Lex Fridman· 2019年9月23日播客 · 2 人对谈The Algorithm Is Already Better. The Clinic Still Uses 1967.嘉宾 Regina Barzilay · 主持 Lex FridmanMIT's Regina Barzilay on why deep learning already beats the breast-cancer 'density' score — and why data, liability, and incentives still will not move.AI in healthcareAI for scienceData quality & curation+3
1:00:11EN
Lex Fridman· 2019年6月17日播客 · 2 人对谈Rosalind Picard: Clippy Never Saw You Frown, and That's the Whole Problem嘉宾 Rosalind Picard · 主持 Lex FridmanThe MIT professor who named affective computing on emotion recognition, privacy, seizure-detecting wearables, and why a device you can take off is safer than a camera you cannot see.多模态与媒体安全与治理Privacy & data governance+3
33:07EN
Lex Fridman· 2018年12月4日播客 · 2 人对谈They Ran an Extension Cord Next Door and Invented Google嘉宾 Eric Schmidt · 主持 Lex FridmanEric Schmidt tells Lex Fridman that Larry and Sergey never held the entrepreneurship meeting: they had a better algorithm, too little power in the dorm, and a $100,000 check.企业与战略Company BuildingAI Strategy+3