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36 篇
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20 张幻灯片40:44EN → 简体中文
3Blue1Brown· 2026年10月16日Grant Sanderson:现在是投身数学的最好时机Grant Sanderson, Constantin Kogler · 3Blue1Brown学生担心 AI 已经解决了数学。Grant Sanderson 却认为恰恰相反:即使机器证明定理的能力超过人类,数学这套制度依然有价值,而新人正迎来一个难得的机会,可以参与重塑它。MathematicsAI for scienceHuman-AI Collaboration+2
39:23EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年10月15日播客 · 2 人对谈The Defenders' Window: Greg Brockman on AI-Generated Knowledge, Drug Discovery, and the New Physics of Cybersecurity主持 Sarah Guo, Elad GilOpenAI's president explains why solving open math problems is a proof point for science, how proactive agents change product form, and why security spending must exceed software spending.安全AI security安全与治理+3
29:26EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年4月3日播客 · 2 人对谈ChatGPT Almost Became a Meeting Bot. Its Co-Creator Is Now Rearranging Atoms主持 Sarah Guo, Elad GilLiam Fedus tells No Priors how Periodic Labs is connecting language models to experiments so materials science can run in a closed loop.企业与战略AI for scienceCompany Building+3
48:14EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年11月13日播客 · 2 人对谈A New Drug Burns $2 Billion and 10 Years. Benchling's CEO Wants AI to Cut That to Three主持 Sarah Guo, Elad GilMost medicines fail in years seven to ten, after hundreds of millions have already gone into the clinic—and Sajith Wickramasekara thinks sending things to space may already be easier.智能体AI for scienceAI in healthcare+3
4 张幻灯片13:30EN → 简体中文
3Blue1Brown· 2025年8月17日AlphaGeometry 如何结合逻辑证明与创造性作图Aleph0Aleph0 讲解了符号几何求解器如何在不使用 AI 的情况下解决大量难题,以及语言模型如何提供辅助作图,让系统达到奥数竞赛水平。MathematicsReasoning & test-time computeAI research+2
2:28:14EN → 简体中文
Lex Fridman· 2025年7月23日播客 · 2 人对谈自然有结构:Demis Hassabis 谈可学习的现实与 AGI嘉宾 Demis Hassabis · 主持 Lex Fridman谷歌 DeepMind 的 CEO 认为,经过进化塑造的系统可以用经典学习方法来建模,而可交互的世界模型正处在通往 AGI 的路上。企业与战略World models通用人工智能+3
49:27EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年7月3日播客 · 2 人对谈From 0.1% to 20%: Chai-2 Turns Antibody Design Into Prompt Engineering主持 Sarah Guo, Elad GilChai Discovery co-founders Joshua Meier and Jack Dent tell Sarah Guo how a generative model now designs antibodies that bind on the first 24-well plate.AI for scienceDrug DiscoveryAI startups & small teams+3
42:09EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年6月26日播客 · 2 人对谈AlphaEvolve found algorithms humans missed for 50 years — then sped up Gemini 23%主持 Sarah Guo, Elad GilGoogle DeepMind’s Pushmeet Kohli and Matej Balog tell No Priors how an evolutionary coding agent searches algorithm space the way AlphaGo searched Go.编程智能体智能体工程评估+3
3:14:34EN → 简体中文
Lex Fridman· 2025年6月14日播客 · 2 人对谈陶哲轩:难题有十个难点,他先关掉九个嘉宾 Terence Tao · 主持 Lex Fridman菲尔兹奖得主陶哲轩与莱克斯·弗里德曼从挂谷针和纳维-斯托克斯方程聊到 Lean 和佩雷尔曼,也谈到为什么今天的 AI 还闻不出一条证明是不是走进了死胡同。MathematicsAI for scienceAI research+3
40:54EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年4月17日播客 · 2 人对谈Discovery rates collapsed tenfold. KoBold still found a 5% copper deposit主持 Sarah Guo, Elad GilJosh Goldman explains why KoBold Metals treats mineral exploration as an information problem, pairing AI with century-old maps to hunt lithium and copper.企业与战略AI for scienceData quality & curation+3
40:33EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年2月27日播客 · 2 人对谈Moderna was only company 18. The real product is the company factory主持 Sarah Guo, Elad GilNoubar Afeyan tells No Priors how Flagship Pioneering turned starting companies into a profession, underwrites scientific uncertainty, and wants AI to run discovery the way Waymo drives.企业与战略Company BuildingAI for science+3
57:41EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年2月25日播客 · 2 人对谈A Hundred Million Cells, Four People, Three Days: Biology's ImageNet Moment主持 Sarah Guo, Elad GilVevo Therapeutics and the Arc Institute open-sourced Tahoe-100M and a 230-million-cell atlas in the same week — and argued that virtual cells, not just protein folders, are the next language model of biology.模型与训练AI for scienceData quality & curation+3
39:22EN
No Priors: AI, Machine Learning, Tech, & Startups· 2024年11月14日播客 · 2 人对谈A Fields Medalist Stuck for Two Hours. AlphaProof Climbed for Three Days.主持 Sarah Guo, Elad GilThe DeepMind team behind AlphaProof tells Sarah Guo and Elad Gil how an AlphaZero-style agent, a Lean verifier, and test-time reinforcement learning reached IMO silver — and why the missing skill is still theory building.智能体Reinforcement LearningReasoning & test-time compute+1
3:19:21EN
Lex Fridman· 2023年12月9日播客 · 2 人对谈Complexity without copies is just randomness: Lee Cronin on assembly theory嘉宾 Lee Cronin · 主持 Lex FridmanThe Glasgow chemist walks Lex Fridman through his controversial Nature paper, a proposed life meter for other worlds, and the claim that the universe is too big to contain its own future.Philosophy of ScienceAstrobiologyOrigin of Life+3
37:01EN
No Priors: AI, Machine Learning, Tech, & Startups· 2023年9月28日播客 · 2 人对谈DNA Is Code, but You Compile It with a Pipette主持 Sarah Guo, Elad GilGinkgo Bioworks CEO Jason Kelly tells No Priors why cells are worth the magic, why biology has no AWS, and why a pandemic should look like cybersecurity.模型与训练AI for scienceBiosecurity+3
2:18:25EN
Lex Fridman· 2023年9月1日播客 · 2 人对谈Grow Everything: Neri Oxman on Giving Nature a Vote嘉宾 Neri Oxman · 主持 Lex FridmanThe designer-scientist who left MIT to build OXMAN talks silkworm pavilions, bees in space, and why the end of human agency might be the start of nature's.RoboticsCreativityScience Communication+3
35:24EN
No Priors: AI, Machine Learning, Tech, & Startups· 2023年8月24日播客 · 2 人对谈The Author of Attention Is All You Need Now Compiles mRNA Like Bytecode主持 Sarah Guo, Elad GilJakob Uszkoreit on why Transformers won, why models spend compute on the wrong things, and why drug discovery has to become generation rather than screening.模型与训练AI for scienceTransformers & attention+2
2:07:04EN → 简体中文
Lex Fridman· 2023年5月28日播客 · 2 人对谈核糖体早就解决了数字化制造嘉宾 Neil Gershenfeld · 主持 Lex FridmanNeil Gershenfeld 与 Lex Fridman 对话,谈图灵(Turing)为什么要把读写头和纸带分开,fab lab 为何是制造领域的“个人电脑时刻”,以及用大约二十种零件培育一个文明需要些什么。开源与社区RoboticsAI research+3
46:57EN
No Priors: AI, Machine Learning, Tech, & Startups· 2023年3月2日播客 · 2 人对谈95% of Drug Programs Fail. Daphne Koller Is Betting Machine Learning on the First Decision主持 Sarah Guo, Elad GilA new medicine still takes more than a decade and well over a billion dollars — and Insitro's founder argues the expensive failures start with the wrong target, indication, or patient.企业与战略AI in healthcareAI for science+3
2:06:25EN
Lex Fridman· 2022年12月19日播客 · 2 人对谈Nathalie Cabrol Wants the Nature of Life, Not Just a Signal from Mars嘉宾 Nathalie Cabrol · 主持 Lex FridmanThe SETI Institute astrobiologist tells Lex Fridman why crater lakes, panspermia, and a Mandelbrot view of language all point to the same question: what life actually is.AstrobiologyPhilosophy of ScienceConsciousness+2
3:43:01EN → 简体中文
Lex Fridman· 2022年9月7日播客 · 2 人对谈把氢和二氧化碳放进试管,热力学想要细胞,却什么也没发生嘉宾 Nick Lane · 主持 Lex Fridman生物化学家 Nick Lane 和 Lex Fridman 聊了水热喷口、线粒体、性和意识,也谈到了为什么细菌应当很常见,文明却很罕见。Origin of LifeAstrobiologyConsciousness+3
2:13:16EN → 简体中文
Lex Fridman· 2022年7月23日播客 · 2 人对谈你身体里的每个原子,都锻造于一颗死去的恒星嘉宾 Martin Rees · 主持 Lex FridmanMartin Rees 与 Lex Fridman 聊了暗物质、外星生命、单程火星之旅,以及为什么这个世纪是第一个由一个物种握有整颗星球命运的世纪。CosmologyAI for scienceScience Communication+3
2:10:39EN → 简体中文
Lex Fridman· 2022年7月1日播客 · 2 人对谈Demis Hassabis:先解决智能,再解决其他一切嘉宾 Demis Hassabis · 主持 Lex FridmanDeepMind 首席执行官告诉 Lex Fridman:图灵测试为什么是一份出错的考卷,AlphaFold 如何改写了生物学,以及射电天空的寂静为何暗示我们或许是孤独的。模型与训练AI research通用人工智能+3
2:55:05EN
Lex Fridman· 2022年5月8日播客 · 2 人对谈Extinction awareness is the human trait Mason wants to carry to the stars嘉宾 Chris Mason · 主持 Lex FridmanCornell geneticist Chris Mason on why seeing our own end creates a duty to engineer life for other worlds — and what a 500-year plan would actually require.AstrobiologyExistential RiskPhilosophy+3
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