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1:59:15ENA Protein Backbone in a Minute: The Real Progress, Bottlenecks, and Risks of AI BiologyAnime : Nathan LabenzThe White House set a thousand-fold lower reporting bar for biological models than for language models—and this conversation shows why that gap already looks prescient.
3:10:49ENMemory Is Not a Replay: Charan Ranganath on Forgetting, Imagination, and False MemoriesInvité : Charan Ranganath · Anime : Lex FridmanA UC Davis neuroscientist explains why the brain is a cheap prediction machine — and why forgetting is how memory works.
1:19:26ENHard Fork on an AI Voice Dispute, Neuralink and Microsoft’s AI PCsInvité : Noland Arbaugh, Karen Weise · Anime : Kevin Roose, Casey NewtonA 2024 episode examines a voice controversy, one participant’s implant experience and computer privacy.
1:00ENNVIDIA and Microsoft’s 2024 RTX AI AnnouncementsMatthew Berman · Forward FutureMatthew Berman reviews Windows AI development, RTX inference improvements and potential uses in games and creative tools.
39:59ENFrom $6 million to $30 million ARR in three months: Garry Tan on YC’s AI boomAnime : Sarah Guo, Elad GilThe Y Combinator president tells Sarah Guo and Elad Gil why this batch looks like nothing he has seen in twenty years, and why a weak elephant is good news for startups.
1:00ENJan Leike's Departure and Criticism of OpenAI's Safety PrioritiesMatthew Berman · Forward FutureIn May 2024, Matthew Berman discusses the departing alignment leader's concerns about OpenAI's safety culture and its preparations for more capable AI.
25:00ENMicrosoft Build 2024: Copilot+ PCs, Phi-3 and AI DemosMatthew Berman, Satya Nadella, Sam Altman, Seth Juarez · Forward FutureMatthew Berman reviews selected Microsoft keynote announcements, product demonstrations and a conversation with Sam Altman.
59:47ENAaron Levie on AI Agents, SaaS Pricing and the Race Between Startups and IncumbentsInvité : Aaron Levie · Anime : Harry StebbingsThe Box CEO considers how AI might change business workflows, employment and software pricing, and why established companies and startups both have a chance.
58:28ENFrom Jailbreaking ChatGPT to Anthropic’s First Prompt Engineer: How Alex Albert Ships Claude 3Anime : Nathan LabenzA year after building jailbreakchat.com, Alex Albert walks Nathan Labenz through Claude 3’s writing, orchestration, character work, and the guardrails app developers still skip.
39:00ENJPMorgan Has 150 Petabytes. GPT-4 Trained on Less Than One.Anime : Sarah Guo, Elad GilScale AI founder Alexandr Wang tells No Priors why easy internet data is exhausted, why expert-plus-model teams still win, and why the path to AGI looks more like curing cancer than inventing a vaccine.
12:50ENTesting Smaug: Hosted 70B Versus a Smaller Local ModelMatthew Berman · Forward FutureMatthew Berman compares two Smaug configurations on Snake, math and reasoning puzzles.
16:47ENMeta Ray-Ban Glasses: A 2024 Review of Hands-Free PhotographyMatthew Berman · Forward FutureMatthew Berman finds the camera more useful than the AI features in his daily routine.
54:32ENNikesh Arora on Competition, Acquisitions and Leading Through ChangeInvité : Nikesh Arora · Anime : Harry StebbingsThe Palo Alto Networks CEO discusses product advantages, acquisition discipline, communication and the personal tradeoffs of leadership.
11:42ENOpenAI’s First Model Spec: Rules, Defaults and a Debate About PersuasionMatthew Berman · Forward FutureMatthew Berman reviews the May 2024 draft’s proposed model behavior and questions its example for correcting a false belief.
56:35ENThey Asked for a Fraction of the 20 Percent and Still Got NoAnime : Nathan LabenzZvi Mowshowitz and Nathan Labenz unpack Jan Leike’s resignation, OpenAI’s broken compute pledge, and what a safety culture looks like when the money does not follow the mission.
0:26ENSarah Tavel on Recruiting as a Venture InvestorInvité : Sarah TavelA venture investor describes building recruiting experience through repetition.
58:18ENJiaona Zhang on Product Scorecards, Strategy and Faster LearningInvité : Jiaona Zhang · Anime : Harry StebbingsLinktree’s product leader explains how KPI trees, weekly scorecards and collaborative rituals connect customer needs to business outcomes.
30:55ENGPT-4o's Early Demos: Voice, Tutoring, Meetings and AccessibilityMatthew Berman, Greg Brockman, Sal Khan, Imran · Forward FutureMatthew Berman examines OpenAI's May 2024 demonstrations and considers what real-time multimodal interaction might enable.
1:00ENMatthew Berman Questions a Proposal for GPU AttestationMatthew Berman · Forward FutureBerman worries that cryptographic hardware checks could become a gatekeeper for AI computing. The short clip does not establish that such a universal approval system exists.
30:16ENSuno's CEO Thinks a Billion People Will Make Music, Not Just Stream ItAnime : Sarah Guo, Elad GilMikey Shulman tells No Priors why Suno skipped speech, charges from day one, and wants the line between listener and creator to disappear.
13:37ENTesting Gemini 1.5 Pro’s Long Context and Video UnderstandingMatthew Berman · Forward FutureMatthew Berman’s 2024 tests show useful image and video summaries alongside blocked code and missed details.
4:01:52ENPaul Rosolie: The Amazon Is a Machine of Death, and Every Heartbeat in It Is Worth SavingInvité : Paul Rosolie · Anime : Lex FridmanDeep in the Peruvian rainforest, the naturalist talks snakes, anacondas, uncontacted tribes, ayahuasca, and why he would rather protect this forest than look for aliens.
27:35ENGoogle I/O 2024: Gemini, Astra and AI Agents Across Google's ProductsMatthew Berman, Sundar Pichai, Demis Hassabis · Forward FutureMatthew Berman reviews Google's 2024 AI announcements, from long-context Gemini and Ask Photos to Project Astra, Veo and proposed Workspace agents.
1:17:14ENDan Siroker on Repeat Founders, Fundraising and Building for Real ProblemsInvité : Dan Siroker · Anime : Harry StebbingsThe Optimizely and Limitless co-founder shares lessons on small teams, investor negotiations and product focus, and explains why founder motivation matters over the long term.
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