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1:02:14ENThe 28-year wait: Robert Langer on rejection, polymers, and a thousand studentsInvitado: Robert Langer · Presenta: Lex FridmanThe MIT bioengineer talks with Lex Fridman about drug delivery, tissue engineering, patents, and the long path from a Folkman hypothesis to Avastin.
1:49:51ENThe Idea Once Called a Devolution Now Powers Almost Every New ChipInvitado: David Patterson · Presenta: Lex FridmanTuring Award winner David Patterson talks with Lex Fridman about RISC, RAID, Moore's Law, open hardware, and why chips without a software stack die.
5:38ENWavey’s Return: Solving a River-Crossing PuzzleSawyer · Jane StreetSawyer solves the first toy-boat crossing with a 5:3 speed ratio, then asks how the answer changes when the return journey starts 60 meters downstream.
6:37ENCrossing the River: A Toy Boat Puzzle and a Snow-Cone SolutionSawyer · Jane StreetA toy boat drifts downstream in a steady current. Sawyer poses a navigation puzzle and solves the previous episode’s cone-and-hemisphere problem.
4:08:58ENThe Man Who Named AGI Wants Superintelligence Raised on CompassionInvitado: Ben Goertzel · Presenta: Lex FridmanLex Fridman talks with Ben Goertzel for four hours about OpenCog, Sophia, SingularityNET, and why a bigger neural net is not a mind.
1:27:29ENResistance Is How You Know the Work MattersInvitado: Steven Pressfield · Presenta: Lex FridmanSteven Pressfield tells Lex Fridman why he writes about Spartans and Alexander — and why the battle that counts is the one against his own ego.
3:35ENSnow Cones and Spheres: A Volume Solution and a New Geometry PuzzleSawyer · Jane StreetSawyer derives the height of a cone with the same volume as a hemisphere, then asks how to reshape the ice with minimal movement.
5:39ENA Snow Cone Geometry Puzzle and a Piggy Bank ProbabilitySawyer · Jane StreetSawyer poses a cone-design challenge and solves a conditional probability problem in two ways.
3:00:18ENOnly a Simulation Can Be ConsciousInvitado: Joscha Bach · Presenta: Lex FridmanJoscha Bach tells Lex Fridman why a neuron cannot feel anything, why existence is the default, and why this dying world is still the best level of the game.
7:03ENGrandma’s Secret College Fund: A Bayes’ Theorem PuzzleSawyer · Jane StreetA random $20 bill reveals information about a hidden deposit. Sawyer poses the new puzzle and solves a DMV probability problem three ways.
7:23ENBayes' Theorem and a Driver's Test Probability PuzzleSawyer · Jane StreetSawyer derives Bayes' theorem, poses a question about test-takers who studied, and solves an earlier card-game probability puzzle.
8:03ENReal Numbers: A Taxi Challenge and Two Ways to Calculate a Sleep ProbabilitySawyer · Jane StreetSawyer poses a consecutive-taxi puzzle and solves a five-night dog-sitting problem with a probability table and a counting argument.
6:50ENThe Perils of Dogsitting: A Probability Warm-UpSawyer · Jane StreetSawyer introduces a five-night dogsitting puzzle and reviews independence, overlapping events and complements with coins and dice.
7:15ENA Balanced Game of War and the Probability of Three TaxisSawyer · Jane StreetSawyer introduces conditional probability through a card-game challenge, then solves an earlier six-car puzzle in two ways.
1:12:36ENKate Darling on Why We Name the Roomba and Mourn the Bomb RobotInvitado: Kate Darling · Presenta: Lex FridmanAn MIT Media Lab researcher argues that our feelings about machines track the history of animal domestication — and that design can steer that instinct for better or worse.
1:29:02ENYou Are Your Own Existence ProofInvitado: Karl Friston · Presenta: Lex FridmanKarl Friston walks Lex Fridman from brain imaging to the free energy principle, arguing that anything which keeps a boundary looks as if it is doing Bayesian inference.
1:22:51ENDensity, Not Demos: Sertac Karaman on Robots That Fly and DriveInvitado: Sertac Karaman · Presenta: Lex FridmanThe MIT roboticist and Optimus Ride co-founder on why sharing space with people is harder than building the machine, and why flying at transportation scale is still the tougher problem.
1:10:16ENMost People See the Black Dress. Stephen Schwarzman Sees the White Lint.Invitado: Stephen Schwarzman · Presenta: Lex FridmanThe Blackstone co-founder on pattern recognition, why entrepreneurship is a team sport, and why the United States cannot afford to sleepwalk through AI.
4:24ENHow DP-3T Uses Bluetooth for Decentralized Contact TracingA 2020 explanation adapted from Nicky Case illustrates how phones can exchange identifiers and check exposure alerts locally.
2:12:36ENAttacks Climb the Stack Until They Land on PeopleInvitado: Dawn Song · Presenta: Lex FridmanDawn Song tells Lex Fridman why the next security crisis is human, how a sticker can rewrite a stop sign, and why data still has no property right.
1:14:54ENWhat Makes the Natural Logarithm Natural?Explore prime density, exponential growth, harmonic sums and the appearance of ln 2.
1:37:28ENWe Are Still Massively Underestimating Deep LearningInvitado: Ilya Sutskever · Presenta: Lex FridmanIlya Sutskever tells Lex Fridman why 2012 was about conviction, why bigger models can get worse before they get better, and what he would do with an AGI.
1:12:03ENMice Don't Get Alzheimer's: Daphne Koller on Disease in a DishInvitado: Daphne Koller · Presenta: Lex FridmanThe Coursera co-founder and insitro CEO on why most diseases are not one disease, how to turn cells into data, and why overconfident neural nets can kill.
1:03:07ENImaginary Interest Rates, Complex Numbers and SpringsGrant Sanderson · 3Blue1BrownA Lockdown Math lesson connects ordinary compound interest to circular motion and an oscillating spring.
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