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44:44EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年7月10日播客 · 2 人对谈$1 of R&D, 35x the return: why Parker Conrad says platforms beat point solutions主持 Sarah Guo, Elad GilThe Rippling CEO on Zenefits, founder psychology, and why shared underlying capabilities—not narrow focus—win in enterprise software.企业与战略Company BuildingProduct Strategy+3
49:27EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年7月3日播客 · 2 人对谈From 0.1% to 20%: Chai-2 Turns Antibody Design Into Prompt Engineering主持 Sarah Guo, Elad GilChai Discovery co-founders Joshua Meier and Jack Dent tell Sarah Guo how a generative model now designs antibodies that bind on the first 24-well plate.AI for scienceDrug DiscoveryAI startups & small teams+3
42:09EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年6月26日播客 · 2 人对谈AlphaEvolve found algorithms humans missed for 50 years — then sped up Gemini 23%主持 Sarah Guo, Elad GilGoogle DeepMind’s Pushmeet Kohli and Matej Balog tell No Priors how an evolutionary coding agent searches algorithm space the way AlphaGo searched Go.编程智能体智能体工程评估+3
45:21EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年6月17日播客 · 2 人对谈Applied Intuition Is Worth $15 Billion, Hasn't Spent Its Capital, and Wants to Be the OS for Cars and Tanks主持 Sarah Guo, Elad GilOn No Priors, Qasar Younis and Peter Ludwig explain the Microsoft playbook for vehicles, why they waited for autonomy techniques to converge, and why Waymo's business model is the question that follows the demo.企业与战略Autonomous DrivingCompany Building+3
41:25EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年6月12日播客 · 2 人对谈Ben Mann thinks superintelligence by 2028 is quite possible主持 Sarah Guo, Elad GilAnthropic's co-founder tells No Priors how Claude 4 unlocked hours of unattended agent work, why the lab built Claude Code, and what an economic Turing test would actually measure.智能体编程智能体智能体工程+3
35:47EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年6月5日播客 · 2 人对谈Fei-Fei Li’s new bet: AI is incomplete without spatial intelligence主持 Sarah Guo, Elad GilThe ImageNet pioneer tells Sarah Guo and Elad Gil why World Labs is building 3D generative foundation models, and why language was only one piece of the puzzle.多模态与媒体Multimodal AI视觉与视频+3
31:34EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年5月15日播客 · 2 人对谈One Company Now Holds as Many Documents as the Entire Early Web主持 Sarah Guo, Elad GilGlean CEO Arvind Jain tells No Priors why enterprise search was a graveyard, how transformers finally made it work, and why a product that searches too well can be too dangerous to sell.RAG 与知识库企业 AISearch & retrieval+3
32:15EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年5月8日播客 · 2 人对谈The Hardest Part of Learning Is Getting Yourself to Start主持 Sarah Guo, Elad GilDuolingo CEO Luis von Ahn tells Sarah Guo how two-minute lessons, streaks, an 83 percent accuracy target, and large language models turned language study into a consumer product.产品与体验Product StrategyAI in Education+3
38:10EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年5月1日播客 · 2 人对谈o3 should wait exactly as long as the answer takes主持 Sarah Guo, Elad GilOpenAI researchers Eric Mitchell and Brandon McKinzie tell No Priors why o3's leap is a chain of tools during reasoning — and why you should send the same prompt a hundred times.模型与训练Reasoning & test-time computeReinforcement Learning+3
30:46EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年4月24日播客 · 2 人对谈Deep Research Turned Web Browsing into a Trainable Problem主持 Sarah Guo, Elad GilOpenAI researcher Isa Fulford explains why a side project on read-only synthesis became an agent, when reinforcement fine-tuning is worth it, and why models will hack the search engine you gave them.智能体智能体工程Reinforcement Learning+3
40:54EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年4月17日播客 · 2 人对谈Discovery rates collapsed tenfold. KoBold still found a 5% copper deposit主持 Sarah Guo, Elad GilJosh Goldman explains why KoBold Metals treats mineral exploration as an information problem, pairing AI with century-old maps to hunt lithium and copper.企业与战略AI for scienceData quality & curation+3
41:52EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年4月10日播客 · 2 人对谈Mercor Hit $100 Million ARR Teaching Models to Hire. Humans Now Write the Exams.主持 Sarah Guo, Elad GilBrendan Foody tells Sarah Guo and Elad Gil how Mercor automated recruiting for frontier labs — and why building evals may become the world's most common knowledge job.企业与战略评估智能体工程+3
38:43EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年3月27日播客 · 2 人对谈Two in Five Doctors Want Out. An On-Call Cardiologist Built the Note That Lets Them Stay主持 Sarah Guo, Elad GilAbridge CEO Shiv Rao on treating the doctor-patient conversation as healthcare's source of truth, and why the company ran straight at the hardest health systems.企业与战略AI in healthcare语音 AI+3
35:14EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年3月20日播客 · 2 人对谈Robots Have No Wikipedia. Chelsea Finn Is Starting With Three Buildings.主持 Sarah Guo, Elad GilPhysical Intelligence’s cofounder tells No Priors why a generalist robot model has to be trained across embodiments, why open-sourcing hardware is a bet against the problem going unsolved, and why humanoids are a little overrated.模型与训练RoboticsData quality & curation+3
50:35EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年3月13日播客 · 2 人对谈Copilot Already Writes Half the Code. GitHub's CEO Says Agents Still Have Four Gates to Clear主持 Sarah Guo, Elad GilThomas Dohmke on agent mode, why median developers are not going anywhere, and how AI is repricing the tools that write software.编程智能体开发流程与测试智能体工程+3
36:24EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年3月5日播客 · 2 人对谈The Man Behind Humanity's Last Exam Says Superintelligence Strategy Should Copy Nukes主持 Sarah Guo, Elad GilDan Hendrycks tells No Priors that labs can only do basic anti-terror refusals, while the real risk-management problem is a geopolitical deterrent he calls mutually assured AI malfunction.安全安全与治理AI security+3
40:33EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年2月27日播客 · 2 人对谈Moderna was only company 18. The real product is the company factory主持 Sarah Guo, Elad GilNoubar Afeyan tells No Priors how Flagship Pioneering turned starting companies into a profession, underwrites scientific uncertainty, and wants AI to run discovery the way Waymo drives.企业与战略Company BuildingAI for science+3
57:41EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年2月25日播客 · 2 人对谈A Hundred Million Cells, Four People, Three Days: Biology's ImageNet Moment主持 Sarah Guo, Elad GilVevo Therapeutics and the Arc Institute open-sourced Tahoe-100M and a 230-million-cell atlas in the same week — and argued that virtual cells, not just protein folders, are the next language model of biology.模型与训练AI for scienceData quality & curation+3
38:14EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年2月20日播客 · 2 人对谈Kyle Vogt Pitched 120 Investors for Cruise. He Will Not Sell the Home-Robot Company主持 Sarah Guo, Elad GilThe Twitch and Cruise co-founder tells Sarah Guo and Elad Gil why Tesla won on business model, why chores should be automated, and why a tiny AI-era team is enough.企业与战略Company BuildingRobotics+3
49:36EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年2月14日播客 · 2 人对谈86 Out of 100: Harvey's Playbook for Selling AI Into Law主持 Sarah Guo, Elad GilWinston Weinberg on a Reddit blind test, expanding-and-collapsing product design, and why Harvey started with century-old firms instead of the mid-market.企业与战略企业 AIProduct Strategy+3
37:58EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年1月23日播客 · 2 人对谈The Forest Will Burn. The Only Question Is on Whose Terms.主持 Sarah Guo, Elad GilConvective Capital’s Bill Clerico walks through why California’s wildfires reached a crescendo, and which wounds are still self-inflicted enough to fix.Venture CapitalPublic Health
30:09EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年1月16日播客 · 2 人对谈Bilt Saved 65 Support Seats. Decagon's Founder Says Most Agent Ideas Still Won't Sell主持 Sarah Guo, Elad GilJesse Zhang on why customer support is the golden agent use case, why instruction following beats o1-style reasoning, and the two filters that kill most agent startups.智能体Customer support automationAgent orchestration+3
31:18EN
No Priors: AI, Machine Learning, Tech, & Startups· 2024年12月19日播客 · 2 人对谈Elias Torres sold a billion-dollar company and called it a failure. Agency is the redo.主持 Sarah Guo, Elad GilThe Drift founder wants $1 billion in revenue with 100 people, one email address, and software that works like a text to someone who actually shows up.企业与战略Company BuildingAI startups & small teams+3
42:21EN
No Priors: AI, Machine Learning, Tech, & Startups· 2024年12月12日播客 · 2 人对谈They Cooled 5,000 Watts per Square Centimeter in Space. Now Diamond Goes on AI Chips主持 Sarah Guo, Elad GilAkash Systems founders Felix Ejeckam and Ty Mitchell tell Sarah Guo why heat is the real limiter on AI, and how lab-grown diamond bonded to semiconductors is their answer.基础设施与部署AI cost & performanceSemiconductors+1
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