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0:26ENThree Common Types of Product LeadersA short overview of platform, core product and specialist roles.
1:07:10ZH → EnglishInstructGPT: From Human Feedback to Language Model AlignmentA guide to InstructGPT’s training process, results, and limitations, from supervised fine-tuning and reward modeling to PPO.
2:40:18ENEvery Living Cell Runs the Same Translation MachineGuest Betül Kaçar · Host Lex FridmanAstrobiologist Betül Kaçar tells Lex Fridman how the tree of life is drawn backward, why nitrogen was fixed only once, and why the genetic code is an alphabet with room for typos.
0:52ENBen Chestnut on His Children Discovering Mailchimp’s SuccessGuest Ben ChestnutThe Mailchimp co-founder shares a family anecdote about wealth and an unexpected magazine cover.
3:42:34ENBhaskar Sunkara Will Not Call Forced Collectivization Anything but a DisasterGuest Bhaskar Sunkara · Host Lex FridmanThe Jacobin founder and Nation president tells Lex Fridman that democratic socialism starts by refusing the No True Scotsman defense of the twentieth century.
0:43ENBarry McCarthy on Peloton’s Brand and Pandemic GrowthGuest Barry McCarthyA 2022 CEO perspective on customer experience and scale.
49:49ENBarry McCarthy on Netflix, Spotify and Leading Peloton’s TurnaroundGuest Barry McCarthy · Host Harry StebbingsThe then Peloton CEO reflects on subscription economics, decision ownership and the emotional demands of a turnaround.
2:06:25ENNathalie Cabrol Wants the Nature of Life, Not Just a Signal from MarsGuest Nathalie Cabrol · Host Lex FridmanThe SETI Institute astrobiologist tells Lex Fridman why crater lakes, panspermia, and a Mandelbrot view of language all point to the same question: what life actually is.
55:47ZH → EnglishNeural Corpus Indexer: Generating Document IDs for RetrievalFrom inverted indexes and two-tower retrieval to NCI’s semantic document IDs, including the corrected data leakage and deployment bottlenecks.
53:50ENBartosz Milewski: A Taste of Type TheoryBartosz Milewski · Reliable SoftwareFrom recursive natural numbers and dependent vectors to identity types and path induction.
58:18ENHadi Partovi on Leadership, Hiring and Teaching Computer ScienceGuest Hadi Partovi · Host Harry StebbingsThe Code.org founder draws on Microsoft, Facebook and startup experience to discuss decision-making, talent and an education system adapting to technology.
1:08:53ENMaggie Hott on Building Enterprise Sales and Hiring the First RepsGuest Maggie Hott · Host Harry StebbingsThe Webflow sales leader explains how to combine self-serve adoption with sales, build outbound and evaluate candidates.
3:40:53ENThe White Pill: See How Bad It Got, Then Keep Going AnywayGuest Michael Malice · Host Lex FridmanOn a Lex Fridman Christmas special, Michael Malice talks through The White Pill — why 19th-century socialism looked scientific and humane, why violence sings its own song, and why cynics who call themselves realists are lying.
58:38ENBen Chestnut on Building Mailchimp, Selling to Intuit and Finding ContentmentGuest Ben Chestnut · Host Harry StebbingsThe Mailchimp co-founder recounts a bootstrapped journey from web design to email marketing, and reflects on leadership, family and life after a sale.
4:05:21ENThe men who trained Mexico's new police later became the ZetasGuest Ed Calderon · Host Lex FridmanEd Calderon tells Lex Fridman what counter-narcotics work in Tijuana taught him about corruption, cartels, and why honesty can be a liability.
1:00:49ENBob Pittman on MTV, iHeartMedia and the Discipline of Consumer BusinessesGuest Bob Pittman · Host Harry StebbingsThe media executive discusses dissent, fast decisions, convenience and the economics behind radio and podcasts.
0:36ENMarty Cagan on Recruiting With a Compelling VisionGuest Marty CaganA short interview excerpt and its context.
3:46:18ENA Ten-Billion-Dollar Error Bar on Other People's MoneyGuest Coffeezilla · Host Lex FridmanYouTube investigator Coffeezilla walks Lex Fridman through how Sam Bankman-Fried's FTX turned a low-risk story into a customer-asset casino.
1:07:17ENMarty Cagan on Product Discovery, Hiring and Empowered TeamsGuest Marty Cagan · Host Harry StebbingsThe Silicon Valley Product Group founder explains how product teams test risk, learn from customers and develop the skills to own outcomes.
2:29:21ENThe Poker Bot That Never Tried to Read a SoulGuest Noam Brown · Host Lex FridmanNoam Brown tells Lex Fridman how a Nash-equilibrium bot crushed heads-up no-limit Hold'em, how Pluribus did it six-handed, and why Diplomacy required an AI that could earn human trust.
1:05:07ENMartin Casado on Building Markets and Rethinking Venture CapitalGuest Martin Casado · Host Harry StebbingsThe a16z general partner explains how an engineer became an investor, why founders need patient category-building, and how venture firms might scale.
1:00:19ENWilliam Hockey on Plaid, Column and Building Financial InfrastructureGuest William Hockey · Host Harry StebbingsThe Plaid co-founder explains why he started a regulated bank, how he thinks about patient hiring and what he expects from the next decade of fintech.
2:59:33ENRoger Gracie Cleared His Mind, Conserved Every Move, and Refused to Be Number TwoGuest Roger Gracie · Host Lex FridmanThe ten-time world champion walks Lex Fridman through the Buchecha rematch, why tapping is intelligence, and how a late-starting chubby kid decided to become the best in the world.
1:16:12ENJason Lemkin on Finding SaaS Investments, Founder Feedback and the Algolia BetGuest Jason Lemkin · Host Harry StebbingsThe SaaStr founder revisits an early investment in Algolia and explains how operator experience, honest competitive analysis and difficult conversations shape his venture practice.
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