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31:39ENThe Skull Is Already the Vat: Max Hodak on Restoring SightModeration: Sarah Guo, Elad GilPatients blinded by macular degeneration put on laser-projector glasses, read books, and fill in Sudoku — because a chip under the retina is sending vision back into the brain.
2:59:44ENTwo Endangered Languages Broke Transformers. Nested Learning Gave Models a Sleep Button.Moderation: Nathan LabenzGoogle researcher Ali Behrouz tells Nathan Labenz how stacking update frequencies — not just layers — and an offline sleep phase could give language models genuine continual learning.
3:18:09ENA Thing Is Alive When Its Goals Outrun Its PartsGast: Michael Levin · Moderation: Lex FridmanTufts biologist Michael Levin tells Lex Fridman that intelligence is a spectrum of persuadability, that even a bubble sort hosts unexpected goals, and that the brain is a thin client to a space physics does not own.
2:42:06ENThe word 'evil' ends the conversationGast: Julia Shaw · Moderation: Lex FridmanCriminal psychologist Julia Shaw talks with Lex Fridman about the dark tetrad, serial killers, jealousy, bisexuality, and why generative AI is the ultimate false-memory machine.
1:13:23ENAn AI Found a GABA-Cancer Link. The Next Step Is Talking to the Cells.Moderation: Nathan LabenzMichael Levin and Leo Pio Lopez on a multilayer embedding that predicted melanoma, a cancer with no mutations, and why biology's real interface is cognitive.
1:59:47ENBCI Would Take 30 Years. This Studio Pivoted to Alignment InsteadModeration: Nathan LabenzJudd Rosenblatt and Mike Vaiana of AE Studio describe two biologically inspired results that do not need interpretability breakthroughs to work.
8:37:34ENThe first Neuralink patient beat a world record with most of his electrodes goneGast: Elon Musk · Moderation: Lex FridmanLex Fridman talks with Elon Musk, the Neuralink team, and Noland Arbaugh about a wireless brain implant, the software that rescued it, and why bandwidth is Musk’s bet on living with AI.
1:47:18ENA Cannabis Clip Sat Quiet for a Year. Then It Hit X.Gast: Andrew Huberman · Moderation: Lex FridmanAndrew Huberman talks with Lex Fridman about online pile-ons, still minds, sharks, ayahuasca, and the slow work of picking who you eat with.
3:10:49ENMemory Is Not a Replay: Charan Ranganath on Forgetting, Imagination, and False MemoriesGast: Charan Ranganath · Moderation: Lex FridmanA UC Davis neuroscientist explains why the brain is a cheap prediction machine — and why forgetting is how memory works.
1:29:14EN55% of People Have Had a Lucid Dream. Prophetic AI Wants the Rest to Have One Every NightModeration: Nathan LabenzProphetic AI co-founders Eric Wollberg and Wesley Berry tell Ate-a-Pi how a headband of EEG and focused ultrasound, steered by a neural transformer, is meant to light up the prefrontal cortex during REM.
2:09:50ENHe stayed up all night playing Civilization 6 with his mindModeration: Nathan LabenzDean W. Ball surveys EEG, ultrasound stimulation, and Neuralink with Nathan Labenz, and argues that merging with machines started decades ago.
2:50:44ENThe Pirahã Have No Word for OneGast: Edward Gibson · Moderation: Lex FridmanMIT psycholinguist Ted Gibson tells Lex Fridman why related words sit together, why language is not thought, and why large language models ace form while missing meaning.
1:34:11ENFrom forty hours in a scanner to one: reconstructing what you see from a shared brain spaceModeration: Nathan LabenzPaul Scotti explains how MindEye2 maps a new person's fMRI into CLIP with an hour of data, and why a linear layer plus better image generators changed the cost of reading minds.
1:25:09ENTwo-Headed Worms, Regenerated Legs, and a Sort That Learned to WaitModeration: Nathan LabenzTufts biologist Michael Levin tells Cognitive Revolution why anatomy is rewritable software, and why he stopped a paper that might have made AI more alive.
1:58:43ENA Worm With 302 Neurons Already Makes Trade-offs. AI Is Still on the Same Ladder.Moderation: Nathan LabenzMax Bennett maps 600 million years of brain evolution onto five breakthroughs — and asks which rungs today's models have actually reached.
1:18:18ENFifteen Thousand Brain Numbers Were Enough to Reconstruct What Someone SawModeration: Nathan LabenzTanishq Mathew Abraham walks through MindEye, the fMRI-to-image system that maps a handful of voxel values onto CLIP and diffusion models.
2:30:28ENAI Only Has a Neocortex: Manolis Kellis on Evolutionary Baggage and Superintelligent PartnersGast: Manolis Kellis · Moderation: Lex FridmanOn his fifth Lex Fridman podcast, the MIT computational biologist argues that layered evolutionary history is what makes humans irreplaceable — and that alignment with AI has to run both ways.
2:39:40ENThe Self That Swoops In to Decide Is Not ThereGast: Annaka Harris · Moderation: Lex FridmanAnnaka Harris tells Lex Fridman why conscious will is an illusion, why a pea tendril is a better picture of choice than an inner agent, and why she now treats consciousness as a possible fundamental of physics.
2:44:16ENIQ at Eleven Predicted Survival at Eighty. Richard Haier on the Finding Psychology Tried to BuryGast: Richard Haier · Moderation: Lex FridmanLex Fridman talks with psychologist Richard Haier about the g factor, The Bell Curve, group differences, and why intelligence research became the most radioactive topic in the field.
3:21:29ENWhen something in the mind breaks, you see what it was forGast: Karl Deisseroth · Moderation: Lex FridmanStanford psychiatrist Karl Deisseroth talks with Lex Fridman about depression, schizophrenia, optogenetics, and why you can treat one symptom without a theory of everything.
2:37:03ENNo One Knows How to Make a PencilGast: Tim Urban · Moderation: Lex FridmanWait But Why's Tim Urban spent five years on a book about why society is tearing itself apart, then sat down with Lex Fridman to talk aliens, Musk, Neuralink, and the war inside a procrastinator's head.
1:42:58ENDon't Talk Conclusions. Talk Data.Gast: Garry Nolan · Moderation: Lex FridmanA Stanford immunologist sat through the brain scans of people who said they had met UFOs—and treats the rest of the subject the same way.
2:46:31ENThe Official Scientific Worldview Is Incompatible With ConsciousnessGast: Philip Goff · Moderation: Lex FridmanDurham philosopher Philip Goff tells Lex Fridman why panpsychism — the view that consciousness is fundamental and ubiquitous — is the least-bad theory of mind.
2:56:42ENSilicon Does Not Emit LightGast: Jeffrey Shainline · Moderation: Lex FridmanNIST physicist Jeffrey Shainline on why a brain-like computer should calculate in superconducting electronics and talk with single photons.
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