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1:06:37ENLegora CEO Max Junestrand on Legal AI, Growth and CompetitionGast: Max Junestrand · Moderation: Harry StebbingsThe founder discusses enterprise adoption, model choices and pricing, as well as his predictions for legal work and the structure of the market.
2:12:31ENMost Caffeine users have no idea they are on a blockchainModeration: Nathan LabenzDFINITY's Dominic Williams tells Nathan Labenz why a tamper-proof, unstoppable cloud is the right backend for AI that writes software from a chat box.
2:25:10ENFine-Tuning Isn't Dead — But It Turned a Helpful Model EvilModeration: Nathan LabenzNathan Labenz on why prompting replaced fine-tuning for most work, what emergent misalignment actually showed, and how he is thinking about jobs, UBI, and AGI.
1:23:12ENVenture Returns, OpenAI Litigation and the Economics of AI GrowthGast: Jason Lemkin, Rory O’Driscoll · Moderation: Harry StebbingsHarry Stebbings, Jason Lemkin and Rory O’Driscoll debate public software prices, research talent, AI advertising and late-stage venture valuations.
39:47ENThe Context at Step 14 Isn't in the CodeLangChain cofounder Harrison Chase on why long-horizon agents finally work—and why traces, harnesses, and first-draft workflows matter more than scaffolding.
1:13:24ENWinston Weinberg on Building Harvey, Enterprise AI and the Art of DealsGast: Winston Weinberg · Moderation: Harry StebbingsHarvey’s co-founder explains how he thinks about founder focus, enterprise adoption, hiring and negotiating while legal AI changes.
2:29:42ENTwelve hooks and thirty files: Daniel Miessler’s personal OS on Claude CodeModeration: Nathan LabenzThe PAI framework treats scaffolding, not the model, as the product — a goal-centered agent stack that Miessler thinks will decide both knowledge-work automation and the next cybersecurity race.
1:52:02ENForward Future Live: AI Engineering, Enterprise Agents, Mathematics and AdoptionMatthew Berman, Nick Wentz, Austen Allred, Aaron Levie, Tudor Achim, Ara Kharazian · Forward FutureAusten Allred, Aaron Levie, Tudor Achim and Ara Kharazian join Matthew Berman and Nick Wentz to discuss how AI is changing work and how to measure its use.
1:30:52ENAI Financing, Venture Scale and the Risks Behind Growth ValuationsGast: Jason Lemkin, Rory O’Driscoll · Moderation: Harry StebbingsHarry Stebbings, Jason Lemkin and Rory O’Driscoll debate model-provider competition, large venture funds and a proposed wealth tax.
1:40:51ENReasoning Models Just Made the Other 80–90% of Enterprise Data UsableModeration: Nathan LabenzSnowflake VP of AI Baris Gultekin on text-to-SQL, RAG, agent design, and why inference has to run next to governed data.
37:00ENThe AlphaChip Team That Laid Out Four TPUs Now Wants Every Company to Be DesignlessAnna Goldie and Azalia Mirhoseini tell Sequoia how an RL floorplanner survived TPU-team anger, learned to draw donut-shaped macros, and became a bet that AI will design chips that then feed AI.
3:06:19ENThey Call Themselves Brothers: First Contact in the AmazonGast: Paul Rosolie · Moderation: Lex FridmanPaul Rosolie tells Lex Fridman about a historic encounter with an uncontacted Amazon clan, a narco war on his river, and the race to buy the last wild corridor.
1:15:19ENAlex Rampell on Venture Scale, Founder Judgment and Durable AI BusinessesGast: Alex Rampell · Moderation: Harry StebbingsThe Andreessen Horowitz investor explains how he weighs ownership, founder motivation and customer retention as venture funds and AI markets grow.
2:05:47ENAI Agents, Open Models and Inference: Forward Future Live with Reflection AI, Microsoft and CerebrasMatthew Berman, Nick Wentz, Ioannis Antonoglou, Sam Schillace, Andrew Feldman · Forward FutureIoannis Antonoglou, Sam Schillace and Andrew Feldman discuss reinforcement learning, software workflows and AI infrastructure with Matthew Berman and Nick Wentz.
1:54:30ENFrom One in Ten Cancer Cells to One in a MillionModeration: Nathan LabenzNathan Labenz's solo AMA updates his son's lymphoma treatment, calls Claude Opus 4.5 software AGI, and ranks the live players of early 2026.
38:28ENOscar Hoglund on Value Chains, AI Tools, and Building Epidemic Sound Without Losing Your LifeGast: Oscar Hoglund · Moderation: Marina MogilkoEpidemic Sound’s cofounder joins Marina Mogilko to explain creative contrast, the move from feature to platform, and the discipline behind sustainable company building.
1:16:21ENJensen Huang’s Year-End Case That Token Costs Can Fall a Billion-Fold Without Killing JobsModeration: Sarah Guo, Elad GilOn No Priors, NVIDIA’s CEO uses radiology, open source, and a $2 trillion R&D budget to argue that 2025’s extremes missed the stack.
1:27:29ENAI Chip Deals, Founder Exits and the Future of WorkGast: Jason Lemkin, Rory O’Driscoll · Moderation: Harry StebbingsHarry Stebbings, Jason Lemkin and Rory O’Driscoll discuss reported Groq and Manus deals, AI compensation, public markets and hiring.
2:26:40ZH张鹏:从清华实验室到智谱上市,如何走向下一代 AIGast: 张鹏 · Moderation: 张小珺智谱 CEO 回顾科技成果转化、GLM 的研发与开源,以及公司如何在长期研究和商业化之间寻找路径。
1:01:38EN13-Hour Coffee and 2x Throughput: Physical Intelligence Crosses the Deployment LineKarol Hausman and Tobi Springenberg tell Sequoia’s Training Data how a general robot brain, plus real-world RL, turned coffee, laundry, and chocolate boxes into jobs that actually run.
32:20ENTheo Browne on Building with Claude CodeTheo Browne · Ping LabsA hands-on look at parallel coding agents, an image studio and a mobile monorepo, including the mistakes and review work behind the demos.
1:06:10ENFuse CEO Alan Chang on Revolut, Energy and Building at SpeedGast: Alan Chang · Moderation: Harry StebbingsChang discusses his management approach, energy policy and Fuse’s growth while Harry Stebbings challenges several of his assumptions.
1:55:02ENAn Index Fund on AGI: How MATS Filters the Next 120 AI Safety ResearchersModeration: Nathan LabenzRyan Kidd, co-executive director of MATS, tells Nathan Labenz why he will not shout a timeline, why every safety technique is also a capabilities technique, and who actually gets hired.
1:18:40ENWhen AI Becomes the Oil Well: Luke Drago on the Intelligence CurseModeration: Nathan LabenzThe Workshop Labs co-founder tells the FLI Podcast why a world of non-human production could recreate the resource curse — and how private data, open weights, and moonshot careers might still break it.
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