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3:17:35ENTen Thousand Comments and 76 Spare Gigawatts: Four Months Writing America's AI Action PlanModeration: Nathan LabenzDean W. Ball spent four months as the White House's senior AI adviser, then left as the Action Plan landed — and explains how a to-do list got written inside a building that cannot run ChatGPT.
57:52ENThey Aimed for 1%. The Lab Hit 20%. Chai Discovery Moved Antibody Design Onto the Computer.Moderation: Jacob EffronJoshua Meier on three waves of AI drug discovery, why Chai-2 behaves like Photoshop for molecules, and why a 1% hit rate was supposed to be enough to change the industry.
11:38ENAI News in August 2025: App Store Dispute, Claude’s Long Context and New ModelsMatthew Berman · Forward FutureMatthew Berman reviews the Musk–Altman exchange, Claude Sonnet 4’s million-token beta, Skywork’s interactive world model and other AI announcements.
39:06ENHe Couldn't Ask His Grandfather What to Do, So He Built a Digital MindOn Sequoia's Training Data, Delphi founder Dara Ladjevardian explains how authorized digital minds turn people into conversational media without replacing them.
10:09ENMatthew Berman on Emotional Attachment to AI After GPT-5’s LaunchMatthew Berman · Forward FutureThe 2025 GPT-5 rollout prompted debate about attachment to older models, sycophancy and the effects of AI companionship.
1:22:51ENMartin Mignot on Index Ventures, Revolut and Investing in FoundersGast: Martin Mignot · Moderation: Harry StebbingsThe Index Ventures partner explains how he evaluates early-stage companies, manages concentrated returns and learns from missed opportunities.
1:14:05ENSullivan boils US-China AI competition down to four buckets, four examples, and a path he calls boringModeration: Nathan LabenzThe former national security advisor treats transformative AI as a planning assumption, not a prophecy, and wants Washington to compete hard with Beijing without pretending a grand bargain will cure the rivalry.
15:08ENGPT-5 at Launch: Routing, Coding, Benchmarks and ReliabilityMatthew Berman · Forward FutureMatthew Berman reviews OpenAI’s 2025 GPT-5 release, its unified ChatGPT experience, benchmark claims and the limitations of model evaluations.
1:10ENTesting a GPT-5-Generated Rubik’s Cube SimulatorMatthew Berman · Forward FutureMatthew Berman prompts GPT-5 to build a Three.js cube simulator and tries its scramble and solve controls at several sizes.
1:43:51ENGPT-5, Cline and SWE-bench: How to Judge AI Coding AgentsMatthew Berman, Matt Wolfe, Ray Fernando, Saoud Razwan, Nick, Ofir, Carlos, John, Kilian · Forward FutureMatthew Berman and guests discuss early GPT-5 impressions, the economics of Cline, and why coding benchmark results depend on the evaluation setup.
1:28:36ENFigma’s IPO, Executive Pay and the Price of AI GrowthGast: Brian Halligan, Jason Lemkin, Rory O’Driscoll · Moderation: Harry StebbingsHubSpot co-founder Brian Halligan joins Harry Stebbings, Jason Lemkin and Rory O’Driscoll to unpack IPO pricing, public ownership and venture strategy.
45:17ENA Click From OpenAI Is 750 Times Harder Than From Google a Decade AgoModeration: Sarah Guo, Elad GilCloudflare CEO Matthew Prince on Content Independence Day, why traffic is a broken proxy for value, and how to price the holes in the models.
25:24ENGPT-5 Tested on Coding, Simulations and Multimodal TasksMatthew Berman · Forward FutureMatthew Berman tries browser applications, visual simulations and image prompts, showing both successes and defects in his early hands-on tests.
1:45:00ENAmerica Holds 45% of the World's Data Centers. Everyone Else Must Build, Buy, or AllyModeration: Nathan LabenzAnjney Midha of a16z maps what “sovereign AI” actually means for companies and for countries that will never own the talent, data, and compute frontier.
1:01:00ENv0 Hit 3 Million Users. Vercel’s CEO Says Pages Will Be Generated On Demand Within Five YearsFor a company that sells cloud hosting and frontend tools, one of the fastest-growing signup channels is ChatGPT.
1:01ENOpenAI’s gpt-oss Release and a Coding BenchmarkMatthew Berman · Forward FutureMatthew Berman introduces two open-weight models and reviews a Codeforces comparison from the launch.
10:28ENOpenAI’s gpt-oss Models: Open Weights, Benchmarks and SafetyMatthew Berman · Forward FutureMatthew Berman reviews the 120b and 20b models, local deployment claims, selected evaluations and the scope of OpenAI’s safety testing.
3:13ENClaude Opus 4.1: Anthropic’s August 2025 Benchmark UpdateMatthew Berman · Forward FutureMatthew Berman reviews the model’s reported coding, reasoning and tool-use results, including one benchmark that declined.
1:30:36ENMiles Dieffenbach on Endowment Investing, Venture Returns and LiquidityGast: Miles Dieffenbach · Moderation: Harry StebbingsThe Carnegie Mellon allocator explains how he compares venture funds with public markets and evaluates fund size, fees and private marks.
1:27:01ENThe $16 Trillion Services Market Is Being Bought, Not Sold ToModeration: Nathan LabenzMarc Bhargava of General Catalyst explains how AI-enabled rollups turn low-margin service firms into compounding, software-like businesses.
1:28:12ENApple, Google and the Race to Fund AI GrowthGast: Jason Lemkin, Rory O’Driscoll · Moderation: Harry StebbingsHarry Stebbings, Jason Lemkin and Rory O’Driscoll debate venture-fund scale, AI infrastructure and how large technology companies can respond to new competition.
36:48ENThe Weekend DeepSeek Dropped, the White House CalledModeration: Sarah Guo, Elad GilSriram Krishnan walks No Priors through America’s 28-page AI Action Plan, a token-share definition of winning, and why the lead over China is too small to take for granted.
4:30:02ENGenghis Khan Never Fought a Battle He Thought He Could LoseGast: Jack Weatherford · Moderation: Lex FridmanAnthropologist Jack Weatherford tells Lex Fridman how an abandoned boy on the Mongolian steppe built the largest contiguous empire in history—and why conquest is only part of the story.
8:17ENASI-Arch: An Automated Search for Neural Network ArchitecturesMatthew Berman · Forward FutureMatthew Berman explains a 2025 research system that proposes, trains and evaluates model designs in an iterative loop.
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