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39:23EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年10月15日播客 · 2 人对谈The Defenders' Window: Greg Brockman on AI-Generated Knowledge, Drug Discovery, and the New Physics of Cybersecurity主持 Sarah Guo, Elad GilOpenAI's president explains why solving open math problems is a proof point for science, how proactive agents change product form, and why security spending must exceed software spending.安全AI security安全与治理+3
1:09:44EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年10月9日播客 · 2 人对谈10,000 GB300s for Four Weeks: Reflection’s Open-Model Ledger主持 Sarah Guo, Elad GilMisha Laskin tells No Priors how Reflection trained Beam, why reinforcement learning outspent pre-training, and why the West needs its own open weights.开源与社区Open-weight modelsReinforcement Learning+3
35:39EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年10月2日播客 · 2 人对谈Compute Scaled a Millionfold. Bandwidth Only 40x. Fractile Wants to Fix That Ratio主持 Sarah Guo, Elad GilIn the summer of 2022, Walter Goodwin founded Fractile in London to build very fast inference chips for the world's largest models.基础设施与部署InferenceAI cost & performance+3
42:44EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年9月24日播客 · 2 人对谈They Paid $7.7 Billion for a Broker — and Intend to Do One Deal a Year主持 Sarah Guo, Elad GilSequence Holdings co-founder Michael Lee tells No Priors why owning a market leader, not selling it software, is how AI actually remakes an incumbent.企业与战略企业 AIAI Strategy+3
38:14EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年9月18日播客 · 2 人对谈Diffusion Will Win Inference: Stefano Ermon Bets Parallel Tokens Beat Custom Silicon主持 Sarah Guo, Elad GilThe Stanford diffusion pioneer tells No Priors why a 50-person lab is training language models that generate many tokens at once — and why that maps to GPUs the way transformers once mapped to training.模型与训练InferenceAI cost & performance+3
45:10EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年9月10日播客 · 2 人对谈76% of Agentic Commerce Is Under 30 Cents — So Coinbase Is Banking the AIs主持 Sarah Guo, Elad GilBrian Armstrong tells Elad Gil how Coinbase became an everything exchange, why card networks cannot price agent-to-agent payments, and what his longevity company is taking into the clinic.智能体Agentic commerce金融 AI+3
37:07EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年9月3日播客 · 2 人对谈Arm’s 98.5% margin business just started shipping chips主持 Sarah Guo, Elad GilCEO Rene Haas tells No Priors why the IP company built a physical CPU for Meta, and why CPUs still sit at the center of AI systems.基础设施与部署Company BuildingAI Strategy+3
34:51EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年8月27日播客 · 2 人对谈Google Paid $10 Million for a Bankrupt Airline’s Data. That’s the Moat.主持 Sarah Guo, Elad GilEon co-founders Ofir Ehrlich and Gonen Stein argue that models and compute are rented commodities — the only asset enterprises can actually keep is their data.企业与战略基础设施与部署Data quality & curation+3
5:15:51EN
Lex Fridman· 2026年8月26日播客 · 2 人对谈DHH Did Not Write a Line of Omarchy Quattro嘉宾 DHH · 主持 Lex FridmanThirteen months after a skeptical conversation with Lex Fridman, the Rails creator describes how Opus 4.5, a swarm of coding agents, and a one-minute Linux installer ended his era of hand-chiseled Ruby.编程智能体Vibe Coding智能体工程+3
31:39EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年8月20日播客 · 2 人对谈The Skull Is Already the Vat: Max Hodak on Restoring Sight主持 Sarah Guo, Elad GilPatients blinded by macular degeneration put on laser-projector glasses, read books, and fill in Sudoku — because a chip under the retina is sending vision back into the brain.Brain-Computer InterfacesAI in healthcareNeuroscience & AI+3
46:08EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年8月13日播客 · 2 人对谈Computers Beat Humans at Chess 30 Years Ago. Chess.com Still Has 250 Million Players主持 Sarah Guo, Elad GilChess.com CEO Erik Allebest tells Sarah Guo how a $56,000 domain became a $200 million business, and why superhuman AI made chess more popular, not obsolete.企业与战略Company BuildingProduct Strategy+3
3:12:58EN
Lex Fridman· 2026年8月12日播客 · 2 人对谈One Cold Shower, Twenty Champions: How Khabib Nurmagomedov Was Forged嘉宾 Khabib Nurmagomedov · 主持 Lex FridmanIn a Makhachkala school gym, seventy men shared one shower, and the water was only cold.Martial ArtsCombat SportsCoaching+3
39:30EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年8月6日播客 · 2 人对谈Three Trillion-Dollar Companies in Five Years. Elad Gil Would Not Bet on a Fleet of Them Next主持 Sarah Guo, Elad GilOn a host-only episode of No Priors, Sarah Guo and Elad Gil separate market size from speed, argue that the best new founders are getting too meek, and treat token budgets as the next corporate power law.企业与战略Company BuildingAI Strategy+3
34:30EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年7月31日播客 · 2 人对谈Netic's Agents Answer the Phone When the Heat Breaks主持 Sarah Guo, Elad GilFounder Melisa Tokmak tells Elad Gil how a two-year-old platform became the AI operations layer for HVAC, roofing, pet care, and other essential services.企业与战略语音 AIWorkflow automation+3
3:46:18EN
Lex Fridman· 2026年7月28日播客 · 2 人对谈If You Take Slavery Out of the Picture, There Is No Civil War嘉宾 Gary Gallagher · 主持 Lex FridmanIn 1860, enslaved people were worth more than every railroad and factory in the United States combined.Political PhilosophyLeadershipHistory
49:20EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年7月23日播客 · 2 人对谈Half of Ask DoorDash Orders Hit a New Restaurant. In Ten Years There Will Be More Dashers, Not Fewer.主持 Sarah Guo, Elad GilCo-founders Andy Fang and Stanley Tang tell Sarah Guo how a conversational ordering interface moved DoorDash's hardest metric, why they built a 300-pound delivery robot in-house, and why autonomy means more human riders, not less.企业与战略RoboticsProduct Strategy+3
41:05EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年7月9日播客 · 2 人对谈There is no moat: Booking’s CEO on a $1 stock, agentic travel, and why AI still doesn’t move the numbers主持 Sarah Guo, Elad GilGlenn Fogel cashed his 1999 bonus, joined Priceline in February 2000, and watched the Nasdaq peak a week later — then spent 25 years turning a near-delisting into a thousand-fold ride he now wants to spend on AI travel agents.企业与战略企业 AIAI Strategy+3
1:01:27EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年7月2日播客 · 2 人对谈Two Years and Four Months to a Live Reactor: Valar Atomics Wants Energy Ten Times Cheaper主持 Sarah Guo, Elad GilIsaiah Taylor walks Sarah Guo through Ward 250 in Utah and argues that nuclear is a hardware-iteration problem, not a paper-design one.基础设施与部署Company Building安全与治理+3
3:51:47EN
Lex Fridman· 2026年6月30日播客 · 2 人对谈Forty-Six Percent of Emperors Were Overthrown. The Empire Lasted Anyway嘉宾 Anthony Kaldellis · 主持 Lex FridmanHistorian Anthony Kaldellis walks Lex Fridman through 2,200 years of Roman history and argues that what we call Byzantium was Rome itself.Political PhilosophyGeopoliticsLeadership
36:19EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年6月26日播客 · 2 人对谈The Benchmark Grid Is Broken: Why Test-Time Compute Has Outrun How We Score Models主持 Sarah Guo, Elad GilOpenAI researcher Noam Brown argues that static leaderboards hide how long a model is allowed to think — and that safety evals, research taste, and the release cycle have not caught up.评估与可观测性评估Benchmarks+3
45:00EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年6月18日播客 · 2 人对谈Lip-Bu Tan took the hardest job in chips to save Intel主持 Sarah Guo, Elad GilThe Cadence veteran and semiconductor investor tells No Priors how he is rebuilding Intel's culture, balance sheet, and foundry, and why he still wants a 10x from here.企业与战略基础设施与部署Leadership+3
42:27EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年6月4日播客 · 2 人对谈Every Company Can Operate at the Frontier — If It Owns the Evals主持 Sarah Guo, Elad GilAt Microsoft Build, Satya Nadella tells No Priors and Latent Space why AI is an ecosystem game, why private evals beat public benchmarks, and why the Azure networking team now asks for tokens instead of headcount.企业与战略企业 AIAI Strategy+3
2:53:42EN
Lex Fridman· 2026年5月29日播客 · 2 人对谈The Moon Is Falling. It Just Keeps Missing.嘉宾 Biggest Mysteries in Physics · 主持 Lex FridmanFermilab physicist Don Lincoln tells Lex Fridman that the history of physics is a history of unification, and that antimatter, dark energy, and a theory of everything still sit far beyond the experiments we can run.Quantum MechanicsScience CommunicationPhilosophy of Science
41:09EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年5月28日播客 · 2 人对谈After Agents Leak Tokens and Wipe Databases, Onyx Trains Small Models to Watch the Big Ones主持 Sarah Guo, Elad GilTwo years ago enterprise security buyers told Maxim Bar Kogan he was too early. Now Fortune 10 companies are calling a sub-100-person Israeli startup because they cannot stop agent adoption — only reduce the chance the next action is illegitimate.安全AI security智能体工程+3
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