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45:17EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年8月7日播客 · 2 人对谈A Click From OpenAI Is 750 Times Harder Than From Google a Decade Ago主持 Sarah Guo, Elad GilCloudflare CEO Matthew Prince on Content Independence Day, why traffic is a broken proxy for value, and how to price the holes in the models.企业与战略AI StrategyPricing Strategy+3
36:48EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年7月31日播客 · 2 人对谈The Weekend DeepSeek Dropped, the White House Called主持 Sarah Guo, Elad GilSriram Krishnan walks No Priors through America’s 28-page AI Action Plan, a token-share definition of winning, and why the lead over China is too small to take for granted.企业与战略AI Strategy基础设施与部署+3
32:59EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年7月24日播客 · 2 人对谈A Hundred People, a Billion in Revenue, and Zero Venture Money主持 Sarah Guo, Elad GilSurge AI founder Edwin Chen on why quality human data is a poetry problem, not a bounding-box problem, and why leaderboards keep training models to write clickbait.评估与可观测性Data quality & curation人工介入验证+3
1:02:54EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年7月17日播客 · 2 人对谈Enterprise Coding Tools Flipped the 80/20. Reflection AI Built the Other Half主持 Sarah Guo, Elad GilFormer Gemini reward-model lead Misha Laskin on Asimov, why comprehension beats generation, and why there is no such thing as generalization—only pulling the test distribution into train.编程智能体智能体工程评估+3
44:44EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年7月10日播客 · 2 人对谈$1 of R&D, 35x the return: why Parker Conrad says platforms beat point solutions主持 Sarah Guo, Elad GilThe Rippling CEO on Zenefits, founder psychology, and why shared underlying capabilities—not narrow focus—win in enterprise software.企业与战略Company BuildingProduct Strategy+3
49:27EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年7月3日播客 · 2 人对谈From 0.1% to 20%: Chai-2 Turns Antibody Design Into Prompt Engineering主持 Sarah Guo, Elad GilChai Discovery co-founders Joshua Meier and Jack Dent tell Sarah Guo how a generative model now designs antibodies that bind on the first 24-well plate.AI for scienceDrug DiscoveryAI startups & small teams+3
42:09EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年6月26日播客 · 2 人对谈AlphaEvolve found algorithms humans missed for 50 years — then sped up Gemini 23%主持 Sarah Guo, Elad GilGoogle DeepMind’s Pushmeet Kohli and Matej Balog tell No Priors how an evolutionary coding agent searches algorithm space the way AlphaGo searched Go.编程智能体智能体工程评估+3
45:21EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年6月17日播客 · 2 人对谈Applied Intuition Is Worth $15 Billion, Hasn't Spent Its Capital, and Wants to Be the OS for Cars and Tanks主持 Sarah Guo, Elad GilOn No Priors, Qasar Younis and Peter Ludwig explain the Microsoft playbook for vehicles, why they waited for autonomy techniques to converge, and why Waymo's business model is the question that follows the demo.企业与战略Autonomous DrivingCompany Building+3
41:25EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年6月12日播客 · 2 人对谈Ben Mann thinks superintelligence by 2028 is quite possible主持 Sarah Guo, Elad GilAnthropic's co-founder tells No Priors how Claude 4 unlocked hours of unattended agent work, why the lab built Claude Code, and what an economic Turing test would actually measure.智能体编程智能体智能体工程+3
35:47EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年6月5日播客 · 2 人对谈Fei-Fei Li’s new bet: AI is incomplete without spatial intelligence主持 Sarah Guo, Elad GilThe ImageNet pioneer tells Sarah Guo and Elad Gil why World Labs is building 3D generative foundation models, and why language was only one piece of the puzzle.多模态与媒体Multimodal AI视觉与视频+3
25:13EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年5月29日播客 · 2 人对谈The AI Table Is Being Cleared: Two or Three Coding Winners, and Forty Years Without a Biotech Giant主持 Sarah Guo, Elad GilSarah Guo and Elad Gil walk through which AI markets have already consolidated, why rival startups still refuse to merge, and the biotech science sitting unused.企业与战略AI StrategyCompany Building+3
31:34EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年5月15日播客 · 2 人对谈One Company Now Holds as Many Documents as the Entire Early Web主持 Sarah Guo, Elad GilGlean CEO Arvind Jain tells No Priors why enterprise search was a graveyard, how transformers finally made it work, and why a product that searches too well can be too dangerous to sell.RAG 与知识库企业 AISearch & retrieval+3
32:15EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年5月8日播客 · 2 人对谈The Hardest Part of Learning Is Getting Yourself to Start主持 Sarah Guo, Elad GilDuolingo CEO Luis von Ahn tells Sarah Guo how two-minute lessons, streaks, an 83 percent accuracy target, and large language models turned language study into a consumer product.产品与体验Product StrategyAI in Education+3
38:10EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年5月1日播客 · 2 人对谈o3 should wait exactly as long as the answer takes主持 Sarah Guo, Elad GilOpenAI researchers Eric Mitchell and Brandon McKinzie tell No Priors why o3's leap is a chain of tools during reasoning — and why you should send the same prompt a hundred times.模型与训练Reasoning & test-time computeReinforcement Learning+3
30:46EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年4月24日播客 · 2 人对谈Deep Research Turned Web Browsing into a Trainable Problem主持 Sarah Guo, Elad GilOpenAI researcher Isa Fulford explains why a side project on read-only synthesis became an agent, when reinforcement fine-tuning is worth it, and why models will hack the search engine you gave them.智能体智能体工程Reinforcement Learning+3
40:54EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年4月17日播客 · 2 人对谈Discovery rates collapsed tenfold. KoBold still found a 5% copper deposit主持 Sarah Guo, Elad GilJosh Goldman explains why KoBold Metals treats mineral exploration as an information problem, pairing AI with century-old maps to hunt lithium and copper.企业与战略AI for scienceData quality & curation+3
41:52EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年4月10日播客 · 2 人对谈Mercor Hit $100 Million ARR Teaching Models to Hire. Humans Now Write the Exams.主持 Sarah Guo, Elad GilBrendan Foody tells Sarah Guo and Elad Gil how Mercor automated recruiting for frontier labs — and why building evals may become the world's most common knowledge job.企业与战略评估智能体工程+3
27:45EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年4月3日播客 · 2 人对谈Nasdaq Down 8% and Ghibli Everywhere: AI Is Already in Inning Three主持 Sarah Guo, Elad GilSarah Guo and Elad Gil on the latest image-gen wow cycle, why public-market panic is mostly noise for software startups, and where specialized models still have room.企业与战略AI StrategyGenerative media+3
38:43EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年3月27日播客 · 2 人对谈Two in Five Doctors Want Out. An On-Call Cardiologist Built the Note That Lets Them Stay主持 Sarah Guo, Elad GilAbridge CEO Shiv Rao on treating the doctor-patient conversation as healthcare's source of truth, and why the company ran straight at the hardest health systems.企业与战略AI in healthcare语音 AI+3
35:14EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年3月20日播客 · 2 人对谈Robots Have No Wikipedia. Chelsea Finn Is Starting With Three Buildings.主持 Sarah Guo, Elad GilPhysical Intelligence’s cofounder tells No Priors why a generalist robot model has to be trained across embodiments, why open-sourcing hardware is a bet against the problem going unsolved, and why humanoids are a little overrated.模型与训练RoboticsData quality & curation+3
50:35EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年3月13日播客 · 2 人对谈Copilot Already Writes Half the Code. GitHub's CEO Says Agents Still Have Four Gates to Clear主持 Sarah Guo, Elad GilThomas Dohmke on agent mode, why median developers are not going anywhere, and how AI is repricing the tools that write software.编程智能体开发流程与测试智能体工程+3
36:24EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年3月5日播客 · 2 人对谈The Man Behind Humanity's Last Exam Says Superintelligence Strategy Should Copy Nukes主持 Sarah Guo, Elad GilDan Hendrycks tells No Priors that labs can only do basic anti-terror refusals, while the real risk-management problem is a geopolitical deterrent he calls mutually assured AI malfunction.安全安全与治理AI security+3
40:33EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年2月27日播客 · 2 人对谈Moderna was only company 18. The real product is the company factory主持 Sarah Guo, Elad GilNoubar Afeyan tells No Priors how Flagship Pioneering turned starting companies into a profession, underwrites scientific uncertainty, and wants AI to run discovery the way Waymo drives.企业与战略Company BuildingAI for science+3
57:41EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年2月25日播客 · 2 人对谈A Hundred Million Cells, Four People, Three Days: Biology's ImageNet Moment主持 Sarah Guo, Elad GilVevo Therapeutics and the Arc Institute open-sourced Tahoe-100M and a 230-million-cell atlas in the same week — and argued that virtual cells, not just protein folders, are the next language model of biology.模型与训练AI for scienceData quality & curation+3
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