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39:23EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年10月15日播客 · 2 人对谈The Defenders' Window: Greg Brockman on AI-Generated Knowledge, Drug Discovery, and the New Physics of Cybersecurity主持 Sarah Guo, Elad GilOpenAI's president explains why solving open math problems is a proof point for science, how proactive agents change product form, and why security spending must exceed software spending.安全AI security安全与治理+3
29:26EN
No Priors: AI, Machine Learning, Tech, & Startups· 2026年4月3日播客 · 2 人对谈ChatGPT Almost Became a Meeting Bot. Its Co-Creator Is Now Rearranging Atoms主持 Sarah Guo, Elad GilLiam Fedus tells No Priors how Periodic Labs is connecting language models to experiments so materials science can run in a closed loop.企业与战略AI for scienceCompany Building+3
48:14EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年11月13日播客 · 2 人对谈A New Drug Burns $2 Billion and 10 Years. Benchling's CEO Wants AI to Cut That to Three主持 Sarah Guo, Elad GilMost medicines fail in years seven to ten, after hundreds of millions have already gone into the clinic—and Sajith Wickramasekara thinks sending things to space may already be easier.智能体AI for scienceAI in healthcare+3
49:27EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年7月3日播客 · 2 人对谈From 0.1% to 20%: Chai-2 Turns Antibody Design Into Prompt Engineering主持 Sarah Guo, Elad GilChai Discovery co-founders Joshua Meier and Jack Dent tell Sarah Guo how a generative model now designs antibodies that bind on the first 24-well plate.AI for scienceDrug DiscoveryAI startups & small teams+3
42:09EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年6月26日播客 · 2 人对谈AlphaEvolve found algorithms humans missed for 50 years — then sped up Gemini 23%主持 Sarah Guo, Elad GilGoogle DeepMind’s Pushmeet Kohli and Matej Balog tell No Priors how an evolutionary coding agent searches algorithm space the way AlphaGo searched Go.编程智能体智能体工程评估+3
40:54EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年4月17日播客 · 2 人对谈Discovery rates collapsed tenfold. KoBold still found a 5% copper deposit主持 Sarah Guo, Elad GilJosh Goldman explains why KoBold Metals treats mineral exploration as an information problem, pairing AI with century-old maps to hunt lithium and copper.企业与战略AI for scienceData quality & curation+3
40:33EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年2月27日播客 · 2 人对谈Moderna was only company 18. The real product is the company factory主持 Sarah Guo, Elad GilNoubar Afeyan tells No Priors how Flagship Pioneering turned starting companies into a profession, underwrites scientific uncertainty, and wants AI to run discovery the way Waymo drives.企业与战略Company BuildingAI for science+3
57:41EN
No Priors: AI, Machine Learning, Tech, & Startups· 2025年2月25日播客 · 2 人对谈A Hundred Million Cells, Four People, Three Days: Biology's ImageNet Moment主持 Sarah Guo, Elad GilVevo Therapeutics and the Arc Institute open-sourced Tahoe-100M and a 230-million-cell atlas in the same week — and argued that virtual cells, not just protein folders, are the next language model of biology.模型与训练AI for scienceData quality & curation+3
39:22EN
No Priors: AI, Machine Learning, Tech, & Startups· 2024年11月14日播客 · 2 人对谈A Fields Medalist Stuck for Two Hours. AlphaProof Climbed for Three Days.主持 Sarah Guo, Elad GilThe DeepMind team behind AlphaProof tells Sarah Guo and Elad Gil how an AlphaZero-style agent, a Lean verifier, and test-time reinforcement learning reached IMO silver — and why the missing skill is still theory building.智能体Reinforcement LearningReasoning & test-time compute+1
37:01EN
No Priors: AI, Machine Learning, Tech, & Startups· 2023年9月28日播客 · 2 人对谈DNA Is Code, but You Compile It with a Pipette主持 Sarah Guo, Elad GilGinkgo Bioworks CEO Jason Kelly tells No Priors why cells are worth the magic, why biology has no AWS, and why a pandemic should look like cybersecurity.模型与训练AI for scienceBiosecurity+3
35:24EN
No Priors: AI, Machine Learning, Tech, & Startups· 2023年8月24日播客 · 2 人对谈The Author of Attention Is All You Need Now Compiles mRNA Like Bytecode主持 Sarah Guo, Elad GilJakob Uszkoreit on why Transformers won, why models spend compute on the wrong things, and why drug discovery has to become generation rather than screening.模型与训练AI for scienceTransformers & attention+2
46:57EN
No Priors: AI, Machine Learning, Tech, & Startups· 2023年3月2日播客 · 2 人对谈95% of Drug Programs Fail. Daphne Koller Is Betting Machine Learning on the First Decision主持 Sarah Guo, Elad GilA new medicine still takes more than a decade and well over a billion dollars — and Insitro's founder argues the expensive failures start with the wrong target, indication, or patient.企业与战略AI in healthcareAI for science+3
56:20EN
No Priors: AI, Machine Learning, Tech, & Startups播客 · 2 人对谈Biohub's Bet: Building Open AI World Models of Biology From Proteins Up to Cells主持 Sarah Guo, Elad GilMark Zuckerberg, Priscilla Chan and Alex Rives explain why Biohub pairs a frontier AI lab with frontier wet-lab biology, and why it releases tools like ESMFold2 as open source.模型与训练AI for scienceOpen-source ecosystems+3