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1:48:57EN
Cognitive Revolution "How AI Changes Everything"· Sep 25, 2026PodcastAI Safety's Real Shortage Is Founders, Not IdeasHost Nathan LabenzHalcyon's Mike McCormick on launching about 30 AI safety, cyber, and biosecurity organizations in three years — and why experienced leaders, not more Google Docs, are the bottleneck.Security & safetyAI SafetyAI startups & small teams+3
31:39EN
No Priors: AI, Machine Learning, Tech, & Startups· Aug 20, 2026Podcast · 2 speakersThe Skull Is Already the Vat: Max Hodak on Restoring SightHost Sarah Guo, Elad GilPatients blinded by macular degeneration put on laser-projector glasses, read books, and fill in Sudoku — because a chip under the retina is sending vision back into the brain.Brain-Computer InterfacesAI in healthcareNeuroscience & AI+3
39:30EN
No Priors: AI, Machine Learning, Tech, & Startups· Aug 6, 2026Podcast · 2 speakersThree Trillion-Dollar Companies in Five Years. Elad Gil Would Not Bet on a Fleet of Them NextHost Sarah Guo, Elad GilOn a host-only episode of No Priors, Sarah Guo and Elad Gil separate market size from speed, argue that the best new founders are getting too meek, and treat token budgets as the next corporate power law.Enterprise & strategyCompany BuildingAI Strategy+3
1:04:14EN
Unsupervised Learning: With Jacob Effron· Jul 31, 2026PodcastThe Man Who Helped Stand Up Colossus in 120 Days Is Betting on an AI That Lives in Your HouseHost Jacob EffronxAI co-founder Igor Babuschkin left to start River AI, arguing coding agents have crossed a threshold, closed labs are getting squeezed, and the next prize is personal, local intelligence.AgentsAI startups & small teamsCompany Building+3
1:13:48EN
Unsupervised Learning: With Jacob Effron· Jul 16, 2026PodcastCarriers Spend $200 Billion a Year. The Money Went Up the StackHost Jacob EffronBenedict Evans tells Jacob Effron why analogizing AI to past platforms is a dead end, and why looking at how those platforms actually made money is not.Enterprise & strategyAI StrategyEnterprise AI+3
42:57EN
No Priors: AI, Machine Learning, Tech, & Startups· May 1, 2026Podcast · 2 speakersInference Is the Last Market: Baseten’s 30x YearHost Sarah Guo, Elad GilCEO Tuhin Srivastava on a billion-dollar inference cloud, why the app layer survives, and a GPU crunch worse than the narrative.Infrastructure & deploymentInferencePost-training+3
29:26EN
No Priors: AI, Machine Learning, Tech, & Startups· Apr 3, 2026Podcast · 2 speakersChatGPT Almost Became a Meeting Bot. Its Co-Creator Is Now Rearranging AtomsHost Sarah Guo, Elad GilLiam Fedus tells No Priors how Periodic Labs is connecting language models to experiments so materials science can run in a closed loop.Enterprise & strategyAI for scienceCompany Building+3
37:00EN
Sequoia Capital· Jan 14, 2026PodcastThe AlphaChip Team That Laid Out Four TPUs Now Wants Every Company to Be DesignlessAnna Goldie and Azalia Mirhoseini tell Sequoia how an RL floorplanner survived TPU-team anger, learned to draw donut-shaped macros, and became a bet that AI will design chips that then feed AI.Infrastructure & deploymentReinforcement LearningAI startups & small teams+3
40:46EN
No Priors: AI, Machine Learning, Tech, & Startups· Dec 19, 2025Podcast · 2 speakersDoctors Are Rushing to AI. Robotics Will Take a Beating First.Host Sarah Guo, Elad GilSarah Guo and Elad Gil’s 2026 forecast for foundation models, IPOs, robotics, consumer agents, and the bets that are not about AI at all.Enterprise & strategyAI StrategyAI startups & small teams+3
41:38EN
No Priors: AI, Machine Learning, Tech, & Startups· Dec 11, 2025Podcast · 2 speakersElevenLabs Hit $300 Million ARR by Building Voice Before Anyone Believed It Was the InterfaceHost Sarah Guo, Elad GilIn Poland, watching a foreign film is a special kind of pain: one narrator, every character, a flat delivery from start to finish.Multimodal & mediaVoice AIGenerative media+3
44:17EN
No Priors: AI, Machine Learning, Tech, & Startups· Dec 5, 2025Podcast · 2 speakersHarvey’s bet: make every law firm AI-first, don’t become oneHost Sarah Guo, Elad GilOn the day Harvey got GPT-4 access, co-founder Winston locked himself in a room for 14 hours and rebuilt his associate workflow by hand.Enterprise & strategyEnterprise AIProduct Strategy+3
39:16EN
No Priors: AI, Machine Learning, Tech, & Startups· Nov 19, 2025Podcast · 2 speakers500 Gloves, 10 Million Trajectories, and a $10,000 Home RobotHost Sarah Guo, Elad GilSunday Robotics co-founders Tony Zhao and Cheng Chi map the gap between a scalable imitation-learning recipe and a machine that actually does the dishes.RoboticsData quality & curationScaling Laws+3
1:55:12EN
Cognitive Revolution "How AI Changes Everything"· Nov 8, 2025Podcast28,000 Documents, a 3B Model, 22 People: The Technical Ledger of Catholic AIHost Nathan LabenzLongbeard CEO Matthew Harvey Sanders tells The Cognitive Revolution how a mission-driven team is aligning models to the Catholic magisterium — and why fine-tuning was not enough.Models & trainingRetrieval-augmented generationFine-tuning+3
1:02:05EN
Unsupervised Learning: With Jacob Effron· Sep 24, 2025Podcast$100 Million Researchers and a $200 Billion xAI: An AI Roundtable Does the MathHost Jacob EffronDatology’s Ari Morcos and Radical Ventures’ Rob Toews argue over whether models are plateauing, whether RL-environment startups will last, and why Google is the lab they would pick.Enterprise & strategyAI StrategyAI startups & small teams+3
44:49EN
Sequoia Capital· Sep 23, 2025PodcastCompanies Keep Asking for AI. Then They Send It Back.Agency founder Elias Torres on why businesses freeze at imperfect answers, and why his third startup aims for a billion in revenue with fewer than 100 people.Enterprise & strategyEnterprise AICompany Building+3
1:51:39EN
Cognitive Revolution "How AI Changes Everything"· Sep 3, 2025PodcastA native ad engine for AI—and the questions it cannot dodgeHost Nathan LabenzRyan Hudson, who sold Honey to PayPal for $4 billion, joins Nathan Labenz to explain ZeroClick’s bet on paid inference-time ads, and the societal incentives he has not yet had to confront.Enterprise & strategyAI in sales & marketingProduct Strategy+3
42:12EN
No Priors: AI, Machine Learning, Tech, & Startups· Aug 21, 2025Podcast · 2 speakersHire the AI First: Andrew Ng on Agentic Workflows and the Scarcity of JudgmentHost Sarah Guo, Elad GilOn No Priors, Andrew Ng argues that agentic AI has made software cheap and fast, which moves the bottleneck to product judgment, error analysis, and the instinct to try an AI before adding headcount.AgentsAgent engineeringCoding agents+3
57:52EN
Unsupervised Learning: With Jacob Effron· Aug 13, 2025PodcastThey Aimed for 1%. The Lab Hit 20%. Chai Discovery Moved Antibody Design Onto the Computer.Host Jacob EffronJoshua Meier on three waves of AI drug discovery, why Chai-2 behaves like Photoshop for molecules, and why a 1% hit rate was supposed to be enough to change the industry.Models & trainingAI for scienceComputational Biology+3
39:06EN
Sequoia Capital· Aug 12, 2025PodcastHe Couldn't Ask His Grandfather What to Do, So He Built a Digital MindOn Sequoia's Training Data, Delphi founder Dara Ladjevardian explains how authorized digital minds turn people into conversational media without replacing them.Product & UXCompany BuildingProduct Strategy+3
1:02:54EN
No Priors: AI, Machine Learning, Tech, & Startups· Jul 17, 2025Podcast · 2 speakersEnterprise Coding Tools Flipped the 80/20. Reflection AI Built the Other HalfHost Sarah Guo, Elad GilFormer Gemini reward-model lead Misha Laskin on Asimov, why comprehension beats generation, and why there is no such thing as generalization—only pulling the test distribution into train.Coding agentsAgent engineeringEvals+3
1:19:46EN
Cognitive Revolution "How AI Changes Everything"· Jul 5, 2025PodcastSuspended from Columbia, He Raised $15 Million to Cheat on EverythingHost Nathan LabenzRoy Lee, founder of Cluely, argues that an undetectable desktop overlay, AI maximalism, and a post-AGI life of 800-year spans are the same bet.Product & UXProduct StrategyAI interface design+3
49:27EN
No Priors: AI, Machine Learning, Tech, & Startups· Jul 3, 2025Podcast · 2 speakersFrom 0.1% to 20%: Chai-2 Turns Antibody Design Into Prompt EngineeringHost Sarah Guo, Elad GilChai Discovery co-founders Joshua Meier and Jack Dent tell Sarah Guo how a generative model now designs antibodies that bind on the first 24-well plate.AI for scienceDrug DiscoveryAI startups & small teams+3
1:24:27EN
Cognitive Revolution "How AI Changes Everything"· Jun 12, 2025Podcast500 Trillion Tokens a Month: How Google Grew 50x in a YearHost Nathan LabenzLogan Kilpatrick returns to Cognitive Revolution to unpack Google's mid-2023 merger, why he expects frontier labs to diverge, and why startups still hold the speed advantage.Enterprise & strategyAI StrategyCompany Building+3
1:00:48EN
Cognitive Revolution "How AI Changes Everything"· Jun 9, 2025PodcastThe Phrase That Alarms a16z’s AI Policy Chief: “It Only Covers a Handful of Companies”Host Nathan LabenzMatt Perault argues that AI rules should target harmful use, not the science of building models, and that “modest” thresholds can lock in an oligopoly.Enterprise & strategyAI RegulationSafety & governance+3
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