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29:26EN
No Priors: AI, Machine Learning, Tech, & Startups· Apr 3, 2026Podcast · 2 speakersChatGPT Almost Became a Meeting Bot. Its Co-Creator Is Now Rearranging AtomsHost Sarah Guo, Elad GilLiam Fedus tells No Priors how Periodic Labs is connecting language models to experiments so materials science can run in a closed loop.Enterprise & strategyAI for scienceCompany Building+3
27:45EN
No Priors: AI, Machine Learning, Tech, & Startups· Apr 3, 2025Podcast · 2 speakersNasdaq Down 8% and Ghibli Everywhere: AI Is Already in Inning ThreeHost Sarah Guo, Elad GilSarah Guo and Elad Gil on the latest image-gen wow cycle, why public-market panic is mostly noise for software startups, and where specialized models still have room.Enterprise & strategyAI StrategyGenerative media+3
22:32EN
No Priors: AI, Machine Learning, Tech, & Startups· Feb 7, 2025Podcast · 2 speakersThe $5.5 Million Was Only the Last MileHost Sarah Guo, Elad GilOn No Priors' 100th episode, Sarah Guo and Elad Gil separate DeepSeek's paper cost from the compute behind it, then walk through OpenAI's Deep Research, Stargate, and their bets for 2025.Models & trainingAI StrategyAI cost & performance+3
23:37EN
No Priors: AI, Machine Learning, Tech, & Startups· Jan 9, 2025Podcast · 2 speakersA Hundred GPUs in Seconds: Why Modal Threw Out Docker and KubernetesHost Sarah Guo, Elad GilErik Bernhardsson tells Elad Gil that AI inference is too bursty for year-long GPU contracts, and that the cloud should feel as fast as a laptop.Infrastructure & deploymentInferenceAI cost & performance+3
26:28EN
No Priors: AI, Machine Learning, Tech, & Startups· Sep 12, 2024Podcast · 2 speakersAPI prices fell 200x. The LLM table still is not set.Host Sarah Guo, Elad GilSarah Guo and Elad Gil, with no guest this week, argue over whether the language-model market has already consolidated — and why falling prices, five-person labs, and AMD’s shopping spree all cut against a simple ending.Enterprise & strategyAI StrategyPricing Strategy+3
29:12EN
No Priors: AI, Machine Learning, Tech, & Startups· Jul 18, 2024Podcast · 2 speakersGoldman says AI will touch 5% of tasks. Two investors take the report apartHost Sarah Guo, Elad GilSarah Guo and Elad Gil use a host-only No Priors episode to dismantle a June 2024 Goldman Sachs note, then map where they would buy, incubate, and hold.Enterprise & strategyAI StrategyAI startups & small teams+3
27:26EN
No Priors: AI, Machine Learning, Tech, & Startups· Jun 20, 2024Podcast · 2 speakersA 40-Person Company With 40,000 Paying Customers Wants to Replace the Camera With AIHost Sarah Guo, Elad GilHeyGen CEO Joshua Xu tells Sarah Guo and Elad Gil how avatars, localization, and a component-wise video stack are meant to knock the camera out of content production.Multimodal & mediaGenerative mediaVision & video+3
29:28EN
No Priors: AI, Machine Learning, Tech, & Startups· May 2, 2024Podcast · 2 speakersDevin Will Not Replace Engineers. It Will Multiply Them, Says Cognition’s Scott WuHost Sarah Guo, Elad GilThe IOI champion behind Devin explains why an AI software engineer that you can watch over the shoulder creates more human engineers, not fewer.Coding agentsAgent engineeringDeveloper productivity+3
24:32EN
No Priors: AI, Machine Learning, Tech, & Startups· Apr 18, 2024Podcast · 2 speakersImage Generation Is Still a Loot Box. Suhail Doshi Wants to Scale PixelsHost Sarah Guo, Elad GilThe Playground AI founder tells No Priors why he skipped language models, how a noise-sampling trick fixed SDXL's muddy brightness, and what a large vision model would actually do.Multimodal & mediaGenerative mediaVision & video+3
26:03EN
No Priors: AI, Machine Learning, Tech, & Startups· Apr 11, 2024Podcast · 2 speakersGPT-4-Class Models Will Be Cheap. The Frontier Will Still Need a Patron.Host Sarah Guo, Elad GilSarah Guo and Elad Gil walk through Mosaic’s Law, Microsoft’s Inflection hire, where the real money sits, and why the first AI wave looks consumer.Enterprise & strategyEnterprise AIAI Strategy+3
29:38EN
No Priors: AI, Machine Learning, Tech, & Startups· Sep 21, 2023Podcast · 2 speakersA Beginner Just Shipped a $250K Business. Professionals Got 30 Percent.Host Sarah Guo, Elad GilReplit CEO Amjad Masad on Ghostwriter, why a 3-billion-parameter model was enough, and the agents he wants earning bounties while you sleep.Coding agentsDeveloper productivityOpen-weight models+3
17:35EN
Lex FridmanPodcastHands Off the Wheel in San Diego: A Comma Two Demo Drive and a Tour of comma.ai's Hardware ShopHost Lex FridmanAfter their podcast conversation, George Hotz takes Lex Fridman on an openpilot drive and then through the comma.ai offices, dashboards, assembly line and compute cluster.Product & UXAutonomous DrivingAI startups & small teams+3
18:32EN
Lenny's PodcastPodcastBuild a Lab Inside Your Product Team: Dan Shipper on Keeping Up With a Moving AI FrontierHost Lenny RachitskyEvery CEO Dan Shipper explains how a tiny, disposable-experiment lab can coexist with a focused product team, and how to move winners from one into the other.Product & UXProduct StrategyAI Product Management+3