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35:39ENCompute Scaled a Millionfold. Bandwidth Only 40x. Fractile Wants to Fix That RatioHost Sarah Guo, Elad GilIn the summer of 2022, Walter Goodwin founded Fractile in London to build very fast inference chips for the world's largest models.
59:13ENAI Agents and the Work Behind Enterprise ProcurementGuest Vladimir Keil · Host Seema Amble, Elena BurgerLio’s Vladimir Keil discusses context, negotiation and multi-agent workflows with a16z.
1:06:36ENTheo’s Guide to Running Coding Agents in ParallelTheo Browne · T3Theo explains his approach to subscription usage, agent delegation, review and remote machines, while acknowledging that parts of his setup may violate provider rules.
45:06ENBarrett Lyon on Rebuilding Internet Privacy and InfrastructureGuest Barrett Lyon · Host Joel de la GarzaThe DoxxNet founder discusses mesh networking, tracking, infrastructure operations and his path from DDoS defense to internet art.
38:28ENAI Agent Security and the Challenge of Recursive Self-ImprovementAI Explained examines reported containment failures, model evaluation and the pressure to accelerate AI research.
1:10:10ENHow Voice Agents Learn the Rhythm of ConversationGuest Tsung-Hsien (Shawn) Wen · Host Tim ScarfePolyAI’s Shawn Wen discusses turn-taking, noisy audio and the work of checking AI output.
1:20:28ENAI Valuations, Talent Wars and the Venture Capital Tradeoffs Behind ThemGuest Jack Altman, Jason Lemkin, Rory O’Driscoll · Host Harry StebbingsHarry Stebbings, Jack Altman, Jason Lemkin and Rory O’Driscoll debate large early-stage bets, open-weight models and the changing market for exits.
1:06ENUsing Meta’s Muse for Meal Planning, Refunds and To-Do ListsMatthew Berman · Forward FutureMatthew Berman demonstrates four tasks for Meta’s personal AI agent, with user approval before selected actions.
1:37:23ENSi Sheppard on the Spanish Conquests of the Aztec and Inca EmpiresGuest Si Sheppard · Host Dwarkesh PatelA discussion of alliances, warfare, disease and the enduring consequences of colonial rule.
38:10ENFrom deepfakes to DNA: how SynthID watermarks AIHannah Fry, Pushmeet Kohli, Jeremy Ratcliffe · Google DeepMindHannah Fry sits down with Pushmeet Kohli and Jeremy Ratcliffe to explain SynthID: a mathematical watermark now used on text, images and video, and being extended to protein sequences so DNA synthesis companies can tell AI-designed molecules from nature.
1:28:08ENThe same H100 costs 3x at AWS, and a four-month-old lab is catching genes the top sequencers missedHost Nathan LabenzA Cognitive Revolution weekly briefing on a possible U.S.–China AI hotline, why hyperscalers charge two to three times as much for identical chips, co-writing a novel with frontier models, and an AI loop that re-diagnosed a child a premier prenatal lab had cleared.
52:49ENJake Paul and The Chainsmokers on Turning Audience Attention into BusinessesGuest Jake Paul, Drew Taggart, Alex Pall · Host Chamath Palihapitiya, Jason CalacanisThe creators discuss boxing promotion, music, venture investing and the hard work behind converting fame into durable results.
14:00ENReid Hoffman on AI Infrastructure Risk and OversightHost Aria Finger, Reid HoffmanA discussion of financing guarantees, audits and proposed shutdown mechanisms.
24:20ENOpenAI DevDay 2026: Early Tests of Dots, Spaces and Fast ModelsClaire Vo reviews announcements and interactive experiments.
33:10ENSam Altman on Agents, Live Documents and Building with AIGuest Sam Altman · Host Dan ShipperA conversation about personal workflows, developer opportunities and fast interaction.
46:07ENUsing Decision Models for Voice, Routing and DataGuest John Lindquist · Host Claire VoJohn Lindquist demonstrates Jev-based application patterns.
10:00ENOpenAI DevDay: Dots, Faster Inference, Codex and ChatGPT SpaceMatthew Berman · Forward FutureMatthew Berman reviews the event’s personal assistant, model, developer tooling and collaboration announcements.
1:42:31ENPeter Mattis on Distributed Databases and Coding with AIGuest Peter Mattis · Host Gergely OroszFrom Gmail and Colossus to CockroachDB, performance and agent-assisted engineering.
30:58ENGPT-6.1 Sol: Cheap, Thorough at Code Review, but Uneven at Long BuildsTheo Browne · T3Theo compares early tests of GPT-6.1 Sol with competing models, from benchmark cost to real code reviews and a 3D game demo.
1:14:20ENLean, AI and the Limits of a Checked ProofGuest Leonardo de Moura · Host Tim ScarfeLean creator Leo de Moura discusses trusted kernels, specifications and human judgment.
16:59ENClaude Sonnet 5.5 Tested: Games, 3D Scenes and a Lower-Cost Opus AlternativeMatthew Berman · Forward FutureMatthew Berman demonstrates generated projects and compares Sonnet’s reported benchmark scores and API prices with Opus.
2:13:27ENHe Wrote a Book to Stop the AI Race — Then Almost Got Addicted to ClaudeHost Nathan LabenzJournalist Garrison Lovely takes the AGI labs at their word, rejects the bubble story, and argues for freezing the frontier until the public actually consents.
1:17:27ENBill Ackman on Family, Investment Risk and Long-Term OwnershipGuest Bill Ackman · Host Shane ParrishThe investor discusses his daughter’s recovery, market uncertainty and how his firm evaluates businesses.
31:46ENClaude Sonnet 5.5: A Fast Research Assistant for Coding AgentsTheo Browne · T3Theo tests Sonnet 5.5 on pricing, reasoning effort, codebase analysis and a 3D game, and finds a surprising role for it alongside larger models.
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