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1:13:23ENAn AI Found a GABA-Cancer Link. The Next Step Is Talking to the Cells.Host Nathan LabenzMichael Levin and Leo Pio Lopez on a multilayer embedding that predicted melanoma, a cancer with no mutations, and why biology's real interface is cognitive.
2:23:05ENWeak Men Aren't Good. They're Just WeakGuest Jordan Peterson · Host Lex FridmanJordan Peterson returns to Lex Fridman's podcast for a two-hour walk from Nietzsche's aphorisms through power, God, envy, psychopathy, and three years of pain that reset every night.
18:24ENTesla’s 2024 “We, Robot” Event: Cybercab, Robovan and Optimus in ContextMatthew Berman, Elon Musk · Forward FutureMatthew Berman reacts to Tesla’s robotaxi showcase and Elon Musk’s predictions, with later context on production and human-assisted robot demonstrations.
1:02:04ENJoão Moura and Matthew Berman on Tesla’s Robotaxi Vision and Building AI AgentsMatthew Berman, João Moura, Elon Musk · Forward FutureA 2024 livestream examines Tesla’s Cybercab and Optimus announcements, then turns to CrewAI, enterprise agent workflows and a small model comparison.
50:51ENEoghan McCabe on Intercom, AI Adoption and Freedom of SpeechGuest Eoghan McCabe · Host Harry StebbingsThe Intercom CEO discusses customer-support AI, remaining private and founder leadership, then debates political expression and misinformation with Harry Stebbings.
26:43ENTesting OpenAI o1 on Planning, Rules and Spatial ReasoningMatthew Berman · Forward FutureMatthew Berman reviews a 2024 pilot study comparing o1-preview, o1-mini and GPT-4 on six planning domains.
21:31ENThe State of AI in 2024: Research, Costs and RisksA historical review of selected report highlights and predictions.
54:45ENA Few Megabytes of Doom and a Few Gigabytes of Model: Why Runway Bets on GeneralizationHost Nathan LabenzCTO Anastasis Germanidis tells The Cognitive Revolution why video is a fuller record of the world than text, why physics shows up without being programmed in, and how a small lab competes with unlimited compute.
1:15:08ENJeff Wang on Public and Private Investing, AI and Sequoia Global EquitiesGuest Jeff Wang · Host Harry StebbingsThe investor explains thematic research, portfolio construction and his 2024 views on AI infrastructure and technology platforms.
1:14:53ZH → EnglishMeng Xing on the Boom and Bust Cycles of Autonomous-Driving InvestmentGuest 孟醒 · Host 张小珺From Shunwei Capital and Didi operations back to venture capital, a practitioner reflects on eight years of change.
38:28ENHalf of Production AI Is RAG. Fine-Tuning Almost Disappeared.Host Sarah Guo, Elad GilBraintrust CEO Ankur Goyal tells No Priors what Notion, Zapier, and Vercel actually ship — and which hyped techniques they quietly dropped.
59:30ENGPT-4 Gets Half Your Data Questions Wrong. Snowflake's Answer Is Systems DesignUsing an off-the-shelf model on enterprise data yields about 45% reliability—one wrong answer out of every two.
1:04:57ENEli Lilly CEO Dave Ricks on GLP-1 Medicines, Pricing and Drug ResearchGuest Dave Ricks · Host David FriedbergA 2024 interview on metabolic drugs, access, long-term treatment and the business of pharmaceutical research.
1:19:00ENEiso Kant on Poolside, Compute and AI for Software DevelopmentGuest Eiso Kant · Host Harry StebbingsPoolside’s CTO explains code-execution feedback, the cost of model development and his company’s ambitions in the AI race.
53:51ENLiora Friedberg on Solving Puzzles in ProductionYaron Minsky, Liora Friedberg · Jane StreetProduction engineering combines live incident response with software, process improvements and a culture that helps people learn from mistakes. Liora Friedberg and Ron Minsky explore the work at Jane Street.
2:29:04ENKeep the Programmer in the Driver's Seat: Cursor's Founders on Tab, Agents, and Zero-Entropy EditingGuest Cursor Team · Host Lex FridmanMichael Truell, Aman Sanger, Sualeh Asif, and Arvid Lunnemark tell Lex Fridman why they forked VS Code, how Tab and Apply actually work, and why most programming still needs a human iterating in real time.
46:23ENHow Holograms Store a Three-Dimensional Scene on FilmA guided explanation of interference, diffraction and the wave algebra behind holographic images.
0:55ENA Hologram That Looks Like a Three-Dimensional SceneA short 3Blue1Brown demonstration shows how a flat recording can produce changing views of a scene.
1:34:16ZH → EnglishJames Lu on Cross-Border Acquisitions, Operations, and RiskGuest 陆复斌 · Host 张小珺The Joffre Capital founder recalls Amazon’s advertising business and acquisitions including Grindr, Investing.com, and Coins.
1:59:47ENBCI Would Take 30 Years. This Studio Pivoted to Alignment InsteadHost Nathan LabenzJudd Rosenblatt and Mike Vaiana of AE Studio describe two biologically inspired results that do not need interpretability breakthroughs to work.
15:00ENMatthew Berman Tests the First ChatGPT Canvas BetaMatthew Berman · Forward FutureA 2024 walkthrough explores side-by-side code and writing edits, unexpected shortcut behavior and platform risk for AI developers.
53:03ENMaria Angelidou-Smith on Product Reviews, Hiring and Building Better TeamsGuest Maria Angelidou-Smith · Host Harry StebbingsThe Personio product and technology leader shares lessons from Meta on product careers, decision-making, resource allocation and leading distributed teams.
1:06:48ENo1 Is Slow and Hard to Use. Percy Liang Still Calls It a Turning PointHost Jacob EffronStanford’s Percy Liang splits OpenAI’s o1 into a disappointing product and the most important research signal in years.
26:08ENFewer Than 3% of Deals Get Investigated. Selling to the Monopolist Is What Triggers the FTC.Host Sarah Guo, Elad GilChair Lina Khan tells No Priors how merger review actually works in AI markets, why open-weight models matter, and why the agency banned most non-competes.
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