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2:14ENWhy Mike Duboe Questions LTV-to-CAC RatiosGuest Mike Duboe · Host Harry StebbingsThe investor favors payback analysis and warns against treating a formula as a strategy.
52:43ENJackie Reses and Kris Dickson on the SVB Failure and Depositor ConfidenceGuest Jackie Reses, Kris Dickson · Host Harry StebbingsDuring the March 2023 crisis, two Lead Bank executives explain the bank run, resolution possibilities and the questions facing depositors.
17:06ENA 2023 Walkthrough of the ChatGPT API and a Python Naming AppMatthew Berman · Forward FutureMatthew Berman explains the GPT-3.5 Turbo launch, tokens and temperature, then runs an older DaVinci-based Flask example.
58:08ENAmjad Masad on Replit, Company Culture and AI-Assisted SoftwareGuest Amjad Masad · Host Harry StebbingsThe Replit founder discusses hiring, developer productivity and the opportunities and risks he saw in AI in 2023.
0:41ENAmjad Masad on Facing Difficult DecisionsThe Replit founder argues that worthwhile outcomes can follow discomfort—and postponing hard decisions can make them harder.
2:10:17ENEmpathy without agreement: Chris Voss on talking to kidnappers and anyone elseGuest Chris Voss · Host Lex FridmanThe former FBI hostage negotiator tells Lex Fridman why feelings, not reason, close deals — and why “that’s right” is the sentence he hunts for.
0:39ENHunter Somerville on Selectivity and Secondary Investment RiskGuest Hunter SomervilleA 2023 clip discusses opportunity, capital structure and information gaps.
1:21:20ENFreeze the eyes and the brain. Train only the optic nerve.Host Nathan LabenzJunnan Li and Dongxu Li tell Nathan Labenz how BLIP cleaned noisy web captions, and how BLIP-2 connected a frozen vision model to a frozen language model in under ten days on one A100.
53:37EN30 models, 42 scenarios, 7 metrics: Percy Liang's public checkup for language modelsHost Sarah Guo, Elad GilA PubMed-only model once led the U.S. medical licensing exam — until a system roughly 200 times larger overtook it.
56:09ENGlen Coates on Product Decisions, Shopify and the Art of StorytellingGuest Glen Coates · Host Harry StebbingsShopify’s product leader explains how teams align on outcomes, keep a platform simple and communicate a product’s value.
14:55ENBuilding a Simple Chatbot With Python or BubbleMatthew Berman · Forward FutureMatthew Berman walks through a historical OpenAI API demo using Colab and Gradio, then a Bubble no-code workflow.
57:15ENAlex Schultz on Meta Growth, Product Experiments and Leading with CandorGuest Alex Schultz · Host Harry StebbingsMeta’s marketing and analytics leader explains retention, Messenger and Reels experiments, and the personal experiences behind his approach to leadership.
3:58ENCreating Imagined Childhood Portraits with MidjourneyMatthew Berman · Forward FutureMatthew Berman demonstrates a 2023 Discord workflow for prompting age-transformed portraits and tests a personal reference image.
2:50:03ENAll I see is silverGuest B-Team Jiu Jitsu · Host Lex FridmanCraig Jones, Nicky Rod, and Nicky Ryan on winning, the Death Squad split, and why a brown belt still will not take a black belt.
12:39ENPrompting for Realistic Images: Portraits, Food, Nature and InteriorsMatthew Berman · Forward FutureMatthew Berman experiments with Midjourney v4 prompts in 2023, showing how subject, lighting and descriptive details affect generated images.
51:40ENHunter Somerville on Venture Secondaries, Liquidity and LP DecisionsGuest Hunter Somerville · Host Harry StebbingsThe StepStone partner explains secondary structures, discounts and allocation pressures in a 2023 venture market with limited liquidity.
1:11:48ENJamie Siminoff on Ring’s Near-Failure, Amazon Sale and MissionGuest Jamie Siminoff · Host Harry StebbingsRing’s founder recounts a cash crisis, the Amazon acquisition and his approach to customer feedback, leadership and invention.
1:26:20ENForty Dollars to Index Joe Rogan: Chroma, Shovels, and the Wright Flyer Era of MLHost Nathan LabenzChroma co-founder Anton Troynikov on embeddings as the storage layer for language-model apps, Stable Attribution, and why machine learning is still flying on intuition.
46:57EN95% of Drug Programs Fail. Daphne Koller Is Betting Machine Learning on the First DecisionHost Sarah Guo, Elad GilA new medicine still takes more than a decade and well over a billion dollars — and Insitro's founder argues the expensive failures start with the wrong target, indication, or patient.
1:52:15ENWhen Ginni Rometty Took IBM, Only Two in Ten Had the Skills the Future RequiredGuest Ginni Rometty · Host Lex FridmanThe former IBM CEO talks with Lex Fridman about changing a century-old company, hiring for curiosity, and using power without turning cold.
4:57ENHow Microsoft Research Used ChatGPT to Guide Robots and DronesMatthew Berman · Forward FutureA 2023 research demonstration combines natural-language instructions, robot APIs and human review to generate code for physical and simulated tasks.
4:56ENGPT-4 Before Its Release: Rumors, Expectations, and What Happened NextMatthew Berman, Sam Altman · Forward FutureIn February 2023, Matthew Berman reviews speculation about GPT-4, Microsoft, multimodality, and release timing. Later announcements clarify several of those predictions.
1:10:33ENDavid Tisch on Seed Fund Math, Valuations and Founder–Investor AlignmentGuest David Tisch · Host Harry StebbingsThe BoxGroup investor debates small checks, reserves and fundraising trade-offs with Harry Stebbings, and explains why he favors a flexible seed strategy.
37:24ENGrace and Nolen's Software Engineering Mock InterviewGrace, Nolen · Jane StreetA unit-conversion graph illustrates how Jane Street interviewers discuss design, code, errors and communication with a candidate.
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