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1:48:29ENHow AI Is Changing Programming: John Crepezzi and Ron MinskyYaron Minsky, John Crepezzi · Jane StreetJane Street’s AI tooling lead and the Signals and Threads host examine agent infrastructure, security, code review and the changing experience of writing software.
1:36:37ENAaron Bauer on Teaching Software Engineering in the Age of AIYaron Minsky, Aaron Bauer · Jane StreetHow learning goals, active practice and editor design shape engineering education when models can generate the code.
1:04:35ENCliff Weitzman on Owning GPUs, Voice AI and Building SpeechifyGast: Cliff Weitzman · Moderation: Harry StebbingsSpeechify's CEO makes the case for owning part of a compute fleet, reflects on a missed business-software opportunity and discusses AI-assisted teams.
5:15:51ENDHH Did Not Write a Line of Omarchy QuattroGast: DHH · Moderation: Lex FridmanThirteen months after a skeptical conversation with Lex Fridman, the Rails creator describes how Opus 4.5, a swarm of coding agents, and a one-minute Linux installer ended his era of hand-chiseled Ruby.
27:19ENThe Turing Test Passed. Warp's CEO Says Nobody Seemed to CareModeration: Sarah Guo, Elad GilZach Lloyd on distilling intelligence without consciousness, why a 40-year-old terminal is the front door for coding agents, and why senior engineers just got more expensive.
1:12:58ENChris Lattner on Mojo and the Search for Portable GPU PerformanceYaron Minsky, Chris Lattner · Jane StreetRon Minsky and Chris Lattner discuss the language and compiler design behind Modular’s effort to make accelerator programming both portable and fast.
1:16:25ENMartin Casado on AI Models, Open Technology and Venture CompetitionGast: Martin Casado · Moderation: Harry StebbingsThe Andreessen Horowitz partner discusses coding tools, open-model policy, labor disruption and how his firm evaluates investments.
6:08:48ENNobody Serious Believes Cookie Banners Help AnyoneGast: DHH · Moderation: Lex FridmanLex Fridman talks with David Heinemeier Hansson for six hours about Ruby, Rails, AI, leaving the cloud, Apple's App Store, and why a small company can still refuse other people's money.
44:44EN$1 of R&D, 35x the return: why Parker Conrad says platforms beat point solutionsModeration: Sarah Guo, Elad GilThe Rippling CEO on Zenefits, founder psychology, and why shared underlying capabilities—not narrow focus—win in enterprise software.
31:03EN21 Ways to Use AI for Coding, Research and Everyday TasksMatthew Berman, Alex · Forward FutureMatthew Berman and editor Alex demonstrate AI workflows for documents, creative work, decisions, travel and reminders.
1:04:56ENVarun Mohan on Windsurf, Coding Agents and Startup FocusGast: Varun Mohan · Moderation: Harry StebbingsThe Windsurf co-founder discusses pivots, rapid product experimentation, coding agents and competition among AI model providers.
5:20:08ENThePrimeagen Would Rather Redesign the Room Than Trust WillpowerGast: ThePrimeagen · Moderation: Lex FridmanLex Fridman talks with Michael Paulson about linked lists, Netflix, Neovim, ADHD, addiction, AI, and the night he says God gave him a conscience.
59:46ENIn Young Cho on Trading Research and Finding Signal in Financial DataYaron Minsky, In Young Cho · Jane StreetIn Young Cho and Ron Minsky discuss the blurred lines between trading, research, and engineering, and why machine learning in markets is difficult.
38:05ENFrom Zero to $20M ARR in Two Months: Bolt's Moat Lives in the BrowserModeration: Sarah Guo, Elad GilStackBlitz CEO Eric Simons tells No Priors how a five-year WebContainers bet, an open-sourced prompt, and a community of non-coders turned Bolt.new into an overnight full-stack generator.
40:33ENCharlie Marsh on uv: Python Dependency Resolution and PerformanceCharlie Marsh · AstralThe Astral founder explains universal lockfiles, Python packaging constraints, and the data structures and cache design behind uv.
1:03:36ENErin Murphy on Designing Tools for Expert UsersYaron Minsky, Erin Murphy · Jane StreetFrom NASA scientists to Jane Street engineers, a UX designer explains how observation, drawing and collaboration reveal what complex tools need to do.
29:28ENDevin Will Not Replace Engineers. It Will Multiply Them, Says Cognition’s Scott WuModeration: Sarah Guo, Elad GilThe IOI champion behind Devin explains why an AI software engineer that you can watch over the shoulder creates more human engineers, not fewer.
55:34ENAndrew Hunter on Performance Engineering for Low-Latency SystemsYaron Minsky, Andrew Hunter · Jane StreetWhy small optimizations pay at hyperscale, why trading latency is harder to measure, and how profiling, tracing, language design and hardware fit together.
32:34ENTen Thousand Certified Engineers in a Year: Google Cloud's Order of Operations for Enterprise AIModeration: Sarah Guo, Elad GilKawal Gandhi, head of generative AI in Google Cloud's Office of the CTO, walks Sarah Guo and Elad Gil through dogfooding, the efficiency-productivity-creativity ladder, and why customer weights are the IP that cannot leak.
29:38ENA Beginner Just Shipped a $250K Business. Professionals Got 30 Percent.Moderation: Sarah Guo, Elad GilReplit CEO Amjad Masad on Ghostwriter, why a 3-billion-parameter model was enough, and the agents he wants earning bounties while you sleep.
38:13ENChatGPT Runs on His Framework. He Still Doesn't Want You Training a ModelModeration: Sarah Guo, Elad GilVercel founder Guillermo Rauch tells No Priors why frontend is the last mile of AI, why first-generation AI frameworks will be rewritten, and why bots are already stealing your tokens.
1:02:17ENPeter Bogart-Johnson on Product Management, Poetry and ListeningYaron Minsky, Peter Bogart-Johnson · Jane StreetA poet and program manager explains how to earn a team’s trust, preserve what works and coordinate change without separating engineers from their users.
44:19ENAI Will Write Ten Times More Code. Someone Still Has to Keep It Running.Moderation: Sarah Guo, Elad GilDatadog co-founder Olivier Pomel on why faster generation moves value from writing software to understanding, securing, and operating it.
41:40ENEvery 10 Milliseconds Cost Copilot 1% of CompletionsModeration: Sarah Guo, Elad GilGitHub Copilot's chief architect, Alex Graveley, walks through how a leftover code model with a sub-10% test pass rate became a product developers would not quit — and what he is building next at Minion AI.
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