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47:14ENBlake Scholl on Supersonic Flight and the Turbines That Could Fund ItJessica Livingston, Carolynn Levy, Blake SchollThe Boom founder explains an engine partnership setback, boomless flight physics, and a proposed power-generation business.
50:37ENAdit Abraham on Why Document Parsing Still Breaks AIGast: Adit Abraham · Moderation: Allen ParkThe Reducto co-founder discusses missing table rows, production evaluation, document editing and growing a company while making a steak sandwich.
17:27ENPhilipp Schmid: Seven Things an AI Coworker NeedsPhilipp Schmid · Google DeepMindA walkthrough of managed agents, skills, credentials and controls, culminating in a scheduled portfolio-audit demo.
18:13ENSid Pednekar: Judgment Is the Scarce Resource in AI AdoptionSid PednekarA framework for choosing valuable problems, building shared capabilities and turning experience into organizational learning.
14:04ENFrank Long on Building AI Investment Workflows Around QualityFrank Long · CoatueCoatue’s Frank Long breaks investing into information, analysis and decision steps, and argues for choosing the right combination of code, models and people.
16:17ENHow Salesforce doubled effective coding output with Claude CodeBoris Cherny, Muralidhar Krishnaprasad, Richard Pack · AnthropicSalesforce describes how it measures AI-assisted work, trains engineers to use agents, and checks the resulting code for defects.
50:50ENFabian Theis on Virtual Cells, Organoids and Closing the Lab LoopGast: Fabian Theis · Moderation: RJ Honicky, Brandon AndersonThe Helmholtz Munich researcher explains perturbation models, biological benchmarks and the work required to connect prediction with experiments.
1:04:32ENHow particle filter SLAM separates a robot’s path from its mapMarco Pavone · Stanford UniversityMarco Pavone derives the conditional independence that makes a particle-based mapping algorithm practical.
17:52ENCameron Wolfe on Evaluating AI When Answers Are SubjectiveCameron Wolfe · NetflixNetflix’s Cameron Wolfe outlines human review, calibrated model judges and production monitoring as a repeatable evaluation loop.
54:08ENVlad Tenev on Ownership, Tokenization and AI TradingGast: Vlad Tenev · Moderation: Sarah GuoRobinhood’s CEO discusses his vision for wider asset ownership, mathematical AI and agentic finance with Sarah Guo.
42:06ENData-Center Power, Financing and Compute: A Panel with Yixing Xu, Alex Yeh and Bruce LiuGast: Yixing Xu, Alex Yeh, Bruce Liu · Moderation: Christina XuBuilders and an investor discuss transmission constraints, delivery delays, lease mismatches and the economics of selling compute.
25:32ENDemis Hassabis warns against AI self-improvement without human reviewGast: Demis Hassabis · Moderation: Reid HoffmanThe Google DeepMind co-founder calls for stronger engineering, shared safety standards and broader debate about AI consciousness.
1:19:29ENScaling Slack and GitHub: Maude Lemaire on Load, Shards and Reliable PlatformsGast: Maude Lemaire · Moderation: Gergely OroszThe principal engineer explains a Slack data migration, realistic load testing, GitHub’s shard constraints and her approach to AI-assisted performance work.
41:02ENTheo on PewDiePie’s Local AI Project, Training Data and Model SafetyTheo, PewDiePieA reaction to the Ajax and Odysius project becomes a discussion of opt-in data, agent traces, fine-tuning and local model tradeoffs.
20:45ENJohn Stecher and Scott Worland on Building AI Systems That Can ChangeScott Worland, John Stecher · Norm AIThe Blackstone and Norm AI CTOs discuss data strategy, evaluations, production controls and when to wait for a better model.
23:55ENSusan Wojcicki’s Family on Her Life and Lung-Cancer ResearchGast: Dennis Troper, Esther Wojcicki, Anne Wojcicki, Janet Wojcicki · Moderation: Marina MogilkoHer family remembers her priorities as a mother and leader and discusses the foundation’s goals for research and earlier detection.
1:01:05ENDiogo Almeida on Decision Models, Benchmark Fatigue and Agent ReliabilityGast: Diogo Almeida · Moderation: Jacob EffronThe creator of Jev discusses structured decisions, model evaluation and the practical problems of building with AI agents.
2:16:39ENGregory Forth on Flores Fossils and Reports of Humanlike BeingsGast: Gregory Forth · Moderation: Joe RoganThe anthropologist discusses fieldwork, local traditions and a disputed hypothesis about a surviving hominin.
52:36ENKim Maida and Mason Egger: Secure Agent Access and Durable ExecutionKim Maida, Mason Egger · KeycardAn expense-approval workshop combines per-call OAuth token exchange with Temporal workflows that recover after a worker fails.
42:40ENDaniel Terhorst-North: Use Generative AI to Go Broader, Not Just FasterDaniel Terhorst-North · Dan North & AssociatesA software practitioner shares how an AI-assisted teaching toolkit led him to “adjacent engineering,” larger test-first steps and external guardrails.
1:43:54ENJoshua Monrad on AI, Biosecurity and Building Layers of DefenseGast: Joshua Monrad · Moderation: Nathan LabenzSentinel Bio’s co-founder discusses uncertain AI-related biological risks, practical safeguards and the long work of global resilience.
15:32ENEmil Chetty on Letting Payment Agents Act Within Customer-Approved BoundariesEmil Chetty · WiseWise’s data and AI product lead describes an immutable job agreement that lets agents choose steps while trusted payment services enforce customer authorization.
39:31ENThariq Shihipar on Closing a Startup and Leaving AnthropicGast: Thariq Shihipar · Moderation: Sarah Chieng, Vivian Midha ShenThe former Claude Code engineer joins SOTA Wives to discuss fundraising, AI labs, content and the social world around technology.
22:01ENReid Hoffman on the Midterms, Political Donations and Tech’s Public ResponsibilitiesModeration: Aria Finger, Reid HoffmanHoffman and Aria Finger discuss their interpretation of Democratic gains, campaign finance and the bargain between data centers and communities.
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