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34:51ENGoogle Paid $10 Million for a Bankrupt Airline’s Data. That’s the Moat.진행자 Sarah Guo, Elad GilEon co-founders Ofir Ehrlich and Gonen Stein argue that models and compute are rented commodities — the only asset enterprises can actually keep is their data.
2:33:35ENA security researcher audits the AI stack that booked a week of guests진행자 Nathan LabenzNathan Labenz walks Daniel Miessler through a 1GB second brain, two named AI employees, and the blast-radius rules that should govern them.
1:43:39ENFive Mutations Could Make a 60% Fatal Bird Flu Spread Between People진행자 Nathan LabenzJohns Hopkins assistant professor Jassi Pannu argues for locking down only the sliver of functional data that teaches models how to make pandemic viruses — and keeping the rest of biology open.
2:03:56EN260 Doctors and 49,000 Criteria: How OpenAI Built Attending-Level Health AI진행자 Nathan LabenzKaran Singhal tells Nathan Labenz how ChatGPT Health was evaluated with physicians, walled off from model training, and aimed at raising both the floor and the ceiling of human health.
1:18:40ENWhen AI Becomes the Oil Well: Luke Drago on the Intelligence Curse진행자 Nathan LabenzThe Workshop Labs co-founder tells the FLI Podcast why a world of non-human production could recreate the resource curse — and how private data, open weights, and moonshot careers might still break it.
1:32:47ENA transformer co-author wants a $160 million model no company owns진행자 Nathan LabenzIllia Polosukhin tells Nathan Labenz how NEAR turned a payments headache into a stack for private inference, shared-revenue training, and AI agents that still answer to a court.
57:45ENThe last thing a totalitarian state can take is love — a reread of Orwell’s 1984진행자 Lex FridmanLex Fridman walks back through Oceania’s machinery of Newspeak, Doublethink, and Room 101, and argues that hate-fueled rebellion is not a way out.
31:29ENRippling skipped the chatbot and stamped employees after 90 days of work진행자 Sarah Guo, Elad GilCOO Matt MacInnis tells No Priors how Talent Signal reads source code, tickets, and customer conversations, then gives managers one calibrated label: high potential, typical, or pay attention.
1:25:10ENA Tenth of Google's Index, 99.9% Recall: How 20 People Built Brave Search진행자 Nathan LabenzJosep M. Pujol walks Cognitive Revolution through Brave's privacy-first index, hybrid retrieval stack, and the Search API Nathan Labenz now wants his own product team to use.
2:09:50ENHe stayed up all night playing Civilization 6 with his mind진행자 Nathan LabenzDean W. Ball surveys EEG, ultrasound stimulation, and Neuralink with Nathan Labenz, and argues that merging with machines started decades ago.
1:44:23ENYou Can Split Your Vote by Issue — and Hand It to an AI진행자 Nathan LabenzTim Reutemann’s 2018 novel Liquid Reign sketches a 2051 democracy built on Swiss citizen initiatives, liquid delegation, and personal AIs you can mute.
3:04:22ENA Ten-Page Memo Told Tucker Carlson Not to Interview Putin게스트 Tucker Carlson · 진행자 Lex FridmanAfter eight days in Moscow, Carlson tells Lex Fridman why he let Vladimir Putin talk, what Navalny’s death does and does not prove, and why he thinks Washington is blocking a settlement in Ukraine.
1:21:50ENA 16K Context Window Holds About 350 Rows. That's Why Tables Need an Agent.진행자 Nathan LabenzGretel AI founder Alex Watson tells Nathan Labenz why most company data is still a spreadsheet, why GPT-4 is the wrong tool for generating it, and how differential privacy lets a model learn a disease without learning a patient.
1:20:06ENAccuracy Dropped From 93% to 7% — Cryptography Wants to Put a Dashcam on AI진행자 Nathan LabenzDaniel Kang explains how zero-knowledge proofs could verify that a model ran as promised, and that a user is human, without exposing weights or biometrics.
1:51:12ENHarvey Silverglate Would Fire 95 Percent of Harvard's Administrators게스트 Harvey Silverglate · 진행자 Lex FridmanThe FIRE co-founder, running as a write-in for Harvard's Board of Overseers, tells Lex Fridman why hate speech is more useful than love speech and why discomfort is the price of a free campus.
1:10:11ENTrying ChatGPT is not the same as using it진행자 Nathan LabenzRachel Woods of The AI Exchange tells Nathan Labenz what she learned from more than a hundred company calls: start inside the business, skip the annual tool contract, and expect to be using only a sliver of what the models can already do.
2:56:02ENThe FBI Never Cracked a Password the Day They Took Silk Road게스트 Chris Tarbell · 진행자 Lex FridmanFormer agent Chris Tarbell tells Lex Fridman how a timezone setting, a Gmail address, and an undercover admin brought down Ross Ulbricht — and why the best hackers are still out there.
3:03:33ENA Robot Is Whatever Still Has Magic게스트 Kate Darling · 진행자 Lex FridmanKate Darling tells Lex Fridman why grocery-store Marty is a real-life Clippy, why animal history is a better guide than humanoid fantasy, and what the Epstein scandal revealed about MIT.
3:53:09ENThe CIA Serves One Customer, and That Customer Is the President게스트 Andrew Bustamante · 진행자 Lex FridmanFormer covert officer Andrew Bustamante walks Lex Fridman through how American intelligence actually works — from the President's Daily Brief to Ukraine, Snowden, and a bar wall in Alabama.
2:29:24ENA Hundred Users Signed Up and Never Came Back게스트 Brian Armstrong · 진행자 Lex FridmanCoinbase CEO Brian Armstrong on the buy button that found product-market fit, why he wants customers to leave his platform, and a company that refuses to be a political square.
3:47:25ENThe Original Internet Godfather Built Trust Among Cybercriminals게스트 Brett Johnson · 진행자 Lex FridmanLex Fridman talks with Brett Johnson about ShadowCrew, social engineering, prison, and why most attacks still use holes everyone already knows about.
2:01:35ENA no-click iPhone exploit sold for $2.5 million. Silence was the only condition.게스트 Nicole Perlroth · 진행자 Lex FridmanNicole Perlroth tells Lex Fridman how zero-days, ransomware, and a privately owned power grid turned curiosity into everyday cyberwar.
1:46:47ENA Perfect Rapid Test Would Fail the FDA. Michael Mina Explains Why That Is the Point게스트 Michael Mina · 진행자 Lex FridmanThe Harvard immunologist tells Lex Fridman that paper-strip antigen tests answer the only public-health question that matters—are you infectious right now—and that one presidential sentence could unlock them.
2:33:37ENNumber Go Up Hides Freedom Go Up: Alex Gladstein on Bitcoin, Dictators, and Human Rights게스트 Alex Gladstein · 진행자 Lex FridmanThe Human Rights Foundation’s chief strategist argues that money was missing from the human-rights conversation, and that Bitcoin is a Trojan horse that turns greed into a tool for individual sovereignty.
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