필터 결과
43개정렬
2:55:05ENExtinction awareness is the human trait Mason wants to carry to the stars게스트 Chris Mason · 진행자 Lex FridmanCornell geneticist Chris Mason on why seeing our own end creates a duty to engineer life for other worlds — and what a 500-year plan would actually require.
1:26:53ENFrancis Collins Cannot Exclude a Lab Leak게스트 Francis Collins · 진행자 Lex FridmanThe outgoing NIH director talks with Lex Fridman about COVID origins, gain-of-function research, Anthony Fauci, vaccines, and why scientific certainty is the wrong pose.
2:59:12ENNature Never Dealt This Card게스트 Rob Reid · 진행자 Lex FridmanIn 2011 two labs independently engineered H5N1 so it could travel through the air between mammals — work Rob Reid tells Lex Fridman should never have been done, and still has not been stopped.
1:41:34ENAging Is a Scratched Disc. David Sinclair Thinks the Body Kept a Backup게스트 David Sinclair · 진행자 Lex FridmanThe Harvard geneticist tells Lex Fridman why aging is information loss, how three genes gave a blind mouse its sight back, and why skipping meals may beat the perfect diet.
2:17:42ENThe building block of life is a bead on a string, not the whole protein게스트 Dmitry Korkin · 진행자 Lex FridmanDmitry Korkin tells Lex Fridman why protein domains, a triangular spike, and a conservative viral shell matter more than the AlphaFold headline, and why a Nobel laureate once answered a midnight forum post.
2:14:55ENHis Wife Calls Him the Radio게스트 Manolis Kellis · 진행자 Lex FridmanMIT computational biologist Manolis Kellis spends the first forty minutes of his fourth Lex Fridman conversation on the songs that formed him, then turns to 42, dinosaurs, and why hunting for meaning matters more than finding it.
2:39:45ENThe obesity gene was never the obesity gene게스트 Manolis Kellis · 진행자 Lex FridmanManolis Kellis tells Lex Fridman how one nucleotide a million bases from FTO rewrote obesity biology, and why human genetics is now driving the study of disease.
2:10:53ENAll Your DNA Would Reach Jupiter a Hundred Times Over게스트 Manolis Kellis · 진행자 Lex FridmanManolis Kellis talks Lex Fridman through the epigenome, Neanderthals, Europa, midlife, and why "are you happy?" is the wrong question.
2:29:24ENWe Are the Descendants of the First Digital Computer게스트 Manolis Kellis · 진행자 Lex FridmanMIT computational biologist Manolis Kellis tells Lex Fridman why life is digital, why any two humans are 99.9 percent identical, and what evolutionary signatures reveal inside SARS-CoV-2.
1:02:14ENThe 28-year wait: Robert Langer on rejection, polymers, and a thousand students게스트 Robert Langer · 진행자 Lex FridmanThe MIT bioengineer talks with Lex Fridman about drug delivery, tissue engineering, patents, and the long path from a Folkman hypothesis to Avastin.
1:12:03ENMice Don't Get Alzheimer's: Daphne Koller on Disease in a Dish게스트 Daphne Koller · 진행자 Lex FridmanThe Coursera co-founder and insitro CEO on why most diseases are not one disease, how to turn cells into data, and why overconfident neural nets can kill.
2:09:02ENA Hundred-Nanometer Machine That Is Not Quite Alive게스트 Dmitry Korkin · 진행자 Lex FridmanDmitry Korkin walks through the structural genomics of SARS-CoV-2, from spike-ACE2 docking to drug-binding sites, vaccines, and cruise-ship simulations, recorded in the first spring of the pandemic.
58:03ENMatt Might on an Algorithm for Precision MedicineMatt Might · University of Alabama at BirminghamA computer scientist describes how genetic data, experimental models and logic programming can help clinicians investigate difficult cases.
57:42ENA Brain Organoid Is Not a Brain게스트 Paola Arlotta · 진행자 Lex FridmanHarvard developmental biologist Paola Arlotta on how the cerebral cortex is built, why timing and mechanical force are part of the code, and why a dish of stem cells is only a window onto that process.
56:20ENBiohub's Bet: Building Open AI World Models of Biology From Proteins Up to Cells진행자 Sarah Guo, Elad GilMark Zuckerberg, Priscilla Chan and Alex Rives explain why Biohub pairs a frontier AI lab with frontier wet-lab biology, and why it releases tools like ESMFold2 as open source.
11:51ENBuilding a Brain: Paola Arlotta on the Choreography of Human Brain Development진행자 Lex FridmanA Harvard stem cell biologist walks through how the embryo builds the cerebral cortex, why order and environment matter, and why development continues into our twenties.
1:03:59ENBuilding a World Model of Life: Biohub's Alex Rives on Why Better Measurement Must Come Before Virtual Cells진행자 Nathan LabenzBiohub's head of science explains why today's virtual cell models fall short, how a $1.8 billion data push aims to fix it, and what a five-year information-level model of the cell could unlock.
1:45:55ENFrom Static Structures to Moving Molecules: Where AI for Protein Design Stands After AlphaFold 3진행자 Nathan LabenzComputational biochemist Amelie Schreiber walks Nathan Labenz through six months of progress in structure prediction, molecular dynamics, peptide and antibody models, and early agent-driven design workflows.









