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2:48:18ENHumans are the only species that skip sleep on purposeゲスト Matt Walker · ホスト Lex FridmanBerkeley sleep scientist Matt Walker talks with Lex Fridman about why we sleep, what caffeine and dreams actually do, and whether passion can justify the health cost of staying up.
2:54:52ENThe Marvelous Proof Still Lives in the Marginホスト Lex FridmanLuís and João Batalha, the brothers behind Fermat's Library, talk with Lex Fridman about hidden backstories, a publishing system that buys its own work twice, and how to sit with a paper until it finally clicks.
2:18:29ENYour Cortex Is 150,000 Brains Voting on a Coffee Cupゲスト Jeff Hawkins · ホスト Lex FridmanJeff Hawkins tells Lex Fridman that intelligence is learning a model of the world, the neocortex is tens of thousands of independent maps that vote, and the fastest path to machine intelligence is reverse-engineering that sheet.
2:42:57ENThe Thousand-Pound Day Was Easy. The Years Before It Were Not.ゲスト Chris Duffin · ホスト Lex FridmanLex Fridman talks with strength athlete and engineer Chris Duffin about squatting and deadlifting 1,000 pounds for reps, stacking the torso like a pressure vessel, and a childhood spent handling live rattlesnakes.
2:30:30ENThe Fallacy of the Successful First Stepゲスト Ishan Misra · ホスト Lex FridmanBerkeley's Jitendra Malik explains why computer vision still looks easy, why fully autonomous driving is not near, and what children know that today's networks do not.
3:01:47ENA hundred miles is a lifetime compressed into one dayゲスト Zach Bitter · ホスト Lex FridmanZach Bitter talks with Lex Fridman about the 100-mile mind, quitting, aerobic training, fat-adapted fueling, and a run across America.
2:13:21ENThe Fourth Deduction Often Turns Out to Be the First Principleゲスト Cumrun Vafa · ホスト Lex FridmanHarvard string theorist Cumrun Vafa on why physicists distrust deduction, how a graviton fell out of a formula nobody wrote for gravity, and what extra dimensions are actually for.
1:44:54ENIf the meat needs a sauce, start over with the animalゲスト Anya Fernald · ホスト Lex FridmanBelcampo co-founder Anya Fernald tells Lex Fridman why cooking is service, why "grass-fed" is an unregulated word, and why regenerative grazing cannot scale without human attention.
2:36:06ENThe Experience Is Not in the Pill. Rick Doblin Spent Decades Proving the Context Is.ゲスト Rick Doblin · ホスト Lex FridmanThe MAPS founder walks Lex Fridman from Huxley's reducing valve to a Phase 3 MDMA trial for PTSD, arguing that legality, safety, and culture matter more than new molecules.
2:39:53ENThere's Something at the Edge of the Solar Systemゲスト Konstantin Batygin · ホスト Lex FridmanCaltech planetary astrophysicist Konstantin Batygin tells Lex Fridman how a hypothesized five-Earth-mass world shepherds the distant Kuiper Belt — and why a photograph would end the argument.
2:37:21ENEmma Goldman Told Lenin the Revolution Was Already Wrongゲスト Michael Malice · ホスト Lex FridmanMichael Malice talks with Lex Fridman about totalitarianism, quiet heroism, and why anarchism is a relationship rather than a place.
2:09:48ENRoger Reaves Flew Cocaine for Escobar. He Says the Money Was Never Worth Itゲスト Roger Reaves · ホスト Lex FridmanLex Fridman talks with one of history's most prolific drug smugglers about the Medellín Cartel, Barry Seal, two shoot-downs, and 33 years in prison.
1:59:28ENSara Walker says “what is life?” is the wrong questionゲスト Sara Walker · ホスト Lex FridmanThe astrobiologist and theoretical physicist tells Lex Fridman that origin-of-life science is stuck on molecules, and that causation, assembly, and planetary-scale information are closer to the real problem.
1:57:38ENThe Best Leadership Uses the Least Forceゲスト Jocko Willink · ホスト Lex FridmanRetired Navy SEAL Jocko Willink talks with Lex Fridman about just war, ego, Musk and Jobs, 4 a.m. discipline, and what jiu jitsu taught him about command.
2:00:48ENNorth Korea Banned the Word for Famine. Yeonmi Park Still Says It.ゲスト Yeonmi Park · ホスト Lex FridmanA North Korean defector tells Lex Fridman how a regime hides hunger, how Animal Farm explained her country, and why she hears echoes of that silence in American life.
1:58:12ENThe Universe Doesn't Sacrifice. That's Why Phosphine Might Mean Life.ゲスト Clara Sousa-Silva · ホスト Lex FridmanQuantum astrochemist Clara Sousa-Silva on the contested Venus detection, a molecule nobody could spell, and why she treats cosmic meaninglessness as a relief.
3:17:09ENWhat Science Is Left When Institutions Decide What Cannot Be Saidゲスト Bret Weinstein · ホスト Lex FridmanEvolutionary biologist Bret Weinstein talks with Lex Fridman about lab-leak evidence, ivermectin, captured public-health agencies, and why the 1% at the fringe is the key to progress.
1:19:49ENAll-In E37: New York’s Primary, Pandemic Origins and App Store Powerホスト Jason Calacanis, Chamath Palihapitiya, David Sacks, David FriedbergA 2021 discussion of election messaging, uncertain pandemic evidence and competing views on antitrust.
2:59:12ENNature Never Dealt This Cardゲスト Rob Reid · ホスト Lex FridmanIn 2011 two labs independently engineered H5N1 so it could travel through the air between mammals — work Rob Reid tells Lex Fridman should never have been done, and still has not been stopped.
4:57:51ENCharles Hoskinson Entered Crypto Expecting Prisonゲスト Charles Hoskinson · ホスト Lex FridmanThe Cardano founder talks with Lex Fridman about proof of stake, formal methods, and why a blockchain should behave like a law of physics.
4:15:19ENExponential tools, Stone Age game theoryゲスト Daniel Schmachtenberger · ホスト Lex FridmanDaniel Schmachtenberger tells Lex Fridman why every leap in physical technology breaks the last social operating system — and why Bretton Woods cannot bind what comes next.
2:41:47ENGeometry Is the Cilantro of Mathゲスト Jordan Ellenberg · ホスト Lex FridmanJordan Ellenberg tells Lex Fridman that the last 150 years of mathematics have been about one question: when two things count as the same.
1:41:34ENAging Is a Scratched Disc. David Sinclair Thinks the Body Kept a Backupゲスト David Sinclair · ホスト Lex FridmanThe Harvard geneticist tells Lex Fridman why aging is information loss, how three genes gave a blind mouse its sight back, and why skipping meals may beat the perfect diet.
3:02:00ENVitalik Buterin Walked Away From Billions of Dog Coins — Then Mapped Ethereum's Next Decadeゲスト Vitalik Buterin · ホスト Lex FridmanIn a three-hour conversation with Lex Fridman, the Ethereum co-founder explains the Shiba Inu dump, proof of stake, rollups, and why he thinks most evil comes from fear.
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