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45:10EN
No Priors: AI, Machine Learning, Tech, & Startups· 10 sept. 2026Podcast · 2 voix76% of Agentic Commerce Is Under 30 Cents — So Coinbase Is Banking the AIsAnime : Sarah Guo, Elad GilBrian Armstrong tells Elad Gil how Coinbase became an everything exchange, why card networks cannot price agent-to-agent payments, and what his longevity company is taking into the clinic.AgentsAgentic commerceIA en finance+3
2:34:18EN
Zhang Xiaojun Podcast· 3 sept. 2026Podcast · 2 voixZeng Ming on AI’s New Era: Why Great Companies and New Organizations EmergeInvité : Zeng Ming · Anime : 张小珺Zeng Ming argues that AI is changing the foundations of business: models will become infrastructure, while new Agent-native applications and organizations create the next wave of value. His advice to founders is to embrace uncertainty, rethink strategy continuously, and build around meaningful work rather than inherited structures.AI StrategyEntreprise et stratégieAgents+2
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No Priors: AI, Machine Learning, Tech, & Startups· 9 avr. 2026Podcast · 2 voixA millionth of a penny: Jeremy Allaire on the payment rails of the agentic economyAnime : Sarah Guo, Elad GilCircle's CEO tells No Priors why stablecoins and a purpose-built chain, not the legacy banking stack, are the money layer for software that buys and sells on its own.AgentsAgentic commerceIA en finance+3
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Lex Fridman· 11 févr. 2026Podcast · 2 voixThe Voice Note His Bot Couldn't Handle — and the Agent That Built Itself AnywayInvité : OpenClaw · Anime : Lex FridmanPeter Steinberger tells Lex Fridman how a one-hour WhatsApp toy became GitHub's fastest-growing project, and what it cost him to keep it open.AgentsPersonal agentsIngénierie d’agents+3
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Lex Fridman· 30 nov. 2025Podcast · 2 voixA Thing Is Alive When Its Goals Outrun Its PartsInvité : Michael Levin · Anime : Lex FridmanTufts biologist Michael Levin tells Lex Fridman that intelligence is a spectrum of persuadability, that even a bubble sort hosts unexpected goals, and that the brain is a thin client to a space physics does not own.AgentsNeuroscience & AIPhilosophy of Mind+3
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No Priors: AI, Machine Learning, Tech, & Startups· 13 nov. 2025Podcast · 2 voixA New Drug Burns $2 Billion and 10 Years. Benchling's CEO Wants AI to Cut That to ThreeAnime : Sarah Guo, Elad GilMost medicines fail in years seven to ten, after hundreds of millions have already gone into the clinic—and Sajith Wickramasekara thinks sending things to space may already be easier.AgentsAI for scienceAI in healthcare+3
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No Priors: AI, Machine Learning, Tech, & Startups· 18 sept. 2025Podcast · 2 voixDecagon Prices AI Support by the Conversation. The Market Is Wages.Anime : Sarah Guo, Elad GilJesse Zhang on six-figure contracts at zero ARR, 60–70% contact-center cuts, and a world where your agent calls the airline’s agent.AgentsAgentic commerceCustomer support automation+3
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No Priors: AI, Machine Learning, Tech, & Startups· 21 août 2025Podcast · 2 voixHire the AI First: Andrew Ng on Agentic Workflows and the Scarcity of JudgmentAnime : Sarah Guo, Elad GilOn No Priors, Andrew Ng argues that agentic AI has made software cheap and fast, which moves the bottleneck to product judgment, error analysis, and the instinct to try an AI before adding headcount.AgentsIngénierie d’agentsAgents de code+3
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No Priors: AI, Machine Learning, Tech, & Startups· 12 juin 2025Podcast · 2 voixBen Mann thinks superintelligence by 2028 is quite possibleAnime : Sarah Guo, Elad GilAnthropic's co-founder tells No Priors how Claude 4 unlocked hours of unattended agent work, why the lab built Claude Code, and what an economic Turing test would actually measure.AgentsAgents de codeIngénierie d’agents+3
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No Priors: AI, Machine Learning, Tech, & Startups· 24 avr. 2025Podcast · 2 voixDeep Research Turned Web Browsing into a Trainable ProblemAnime : Sarah Guo, Elad GilOpenAI researcher Isa Fulford explains why a side project on read-only synthesis became an agent, when reinforcement fine-tuning is worth it, and why models will hack the search engine you gave them.AgentsIngénierie d’agentsReinforcement Learning+3
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No Priors: AI, Machine Learning, Tech, & Startups· 16 janv. 2025Podcast · 2 voixBilt Saved 65 Support Seats. Decagon's Founder Says Most Agent Ideas Still Won't SellAnime : Sarah Guo, Elad GilJesse Zhang on why customer support is the golden agent use case, why instruction following beats o1-style reasoning, and the two filters that kill most agent startups.AgentsCustomer support automationAgent orchestration+3
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No Priors: AI, Machine Learning, Tech, & Startups· 14 nov. 2024Podcast · 2 voixA Fields Medalist Stuck for Two Hours. AlphaProof Climbed for Three Days.Anime : Sarah Guo, Elad GilThe DeepMind team behind AlphaProof tells Sarah Guo and Elad Gil how an AlphaZero-style agent, a Lean verifier, and test-time reinforcement learning reached IMO silver — and why the missing skill is still theory building.AgentsReinforcement LearningReasoning & test-time compute+1
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No Priors: AI, Machine Learning, Tech, & Startups· 19 sept. 2024Podcast · 2 voixA Call Center Contact Costs $13. A Company Agent Can Do It for Under a DollarAnime : Sarah Guo, Elad GilSierra cofounder and OpenAI chairman Bret Taylor tells No Priors why branded customer agents are shovel-ready, why RAG demos are not products, and how AI software should charge for the job done.AgentsIngénierie d’agentsCustomer support automation+3
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No Priors: AI, Machine Learning, Tech, & Startups· 28 mars 2024Podcast · 2 voixFrom a side project to 700 integrations: Harrison Chase on what still blocks agentsAnime : Sarah Guo, Elad GilThe LangChain CEO walks through a two-year churn of patterns, and why memory, planning, and few-shot data still matter more than swapping models.AgentsIngénierie d’agentsAgent memory+3
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No Priors: AI, Machine Learning, Tech, & Startups· 16 nov. 2023Podcast · 2 voixFourteen People, $200 Million of Compute, and the Reliability Bottleneck for AgentsAnime : Sarah Guo, Elad GilImbue co-founders Kanjun Qiu and Josh Albrecht on why agents fail, why language models cannot learn general algorithms, and why they are spending a giant round on GPUs rather than headcount.AgentsAgents de codeIngénierie d’agents+3
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No Priors: AI, Machine Learning, Tech, & Startups· 15 sept. 2023Podcast · 2 voixThe Transformer Co-Author Who Wants to Give AI a WalletAnime : Sarah Guo, Elad GilIllia Polosukhin, co-author of Attention Is All You Need and co-founder of NEAR, argues that a blockchain account turns a language-model agent into an economic actor that can hire people and other AIs.AgentsAgentic commerceAuthentification des agents+3
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No Priors: AI, Machine Learning, Tech, & Startups· 11 mai 2023Podcast · 2 voixNine orders of magnitude later, he shipped a companion, not an oracleAnime : Sarah Guo, Elad GilDeepMind co-founder Mustafa Suleyman tells No Priors why Inflection’s first product is a personal AI that sits in your corner, and why the missing piece is a router, not a bigger model.AgentsPersonal agentsAI interface design+3
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No Priors: AI, Machine Learning, Tech, & Startups· 2 févr. 2023Podcast · 2 voixForty games of Diplomacy, and nobody spotted the bot: Noam Brown’s 100,000x lessonAnime : Sarah Guo, Elad GilMeta’s Noam Brown tells Sarah Guo and Elad Gil how Cicero negotiated in English for 40 games on a tiny web community — and why thinking at decision time beat three years of scaling.AgentsAI researchReasoning & test-time compute+3
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Lex Fridman· 6 déc. 2022Podcast · 2 voixThe Poker Bot That Never Tried to Read a SoulInvité : Noam Brown · Anime : Lex FridmanNoam Brown tells Lex Fridman how a Nash-equilibrium bot crushed heads-up no-limit Hold'em, how Pluribus did it six-handed, and why Diplomacy required an AI that could earn human trust.AgentsReinforcement LearningMulti-agent systems+1
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Lex Fridman· 21 oct. 2020Podcast · 2 voixThe IQ required to destroy the world drops by one point every yearInvité : George Hotz · Anime : Lex FridmanGeorge Hotz on Fermi's paradox, hacking the simulation, and teaching cars to drive with neural nets.AgentsAutonomous DrivingSimulation Hypothesis+3
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Lex Fridman· 22 juin 2020Podcast · 2 voixThe Man Who Named AGI Wants Superintelligence Raised on CompassionInvité : Ben Goertzel · Anime : Lex FridmanLex Fridman talks with Ben Goertzel for four hours about OpenCog, Sophia, SingularityNET, and why a bigger neural net is not a mind.AgentsAGIAI research+3
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Lex Fridman· 5 juin 2020Podcast · 2 voixKate Darling on Why We Name the Roomba and Mourn the Bomb RobotInvité : Kate Darling · Anime : Lex FridmanAn MIT Media Lab researcher argues that our feelings about machines track the history of animal domestication — and that design can steer that instinct for better or worse.AgentsSécurité et gouvernanceRobotics+3
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Lex Fridman· 19 mars 2020Podcast · 2 voixMaybe people are rational under different assumptionsInvité : Anca Dragan · Anime : Lex FridmanAnca Dragan talks with Lex Fridman about inverse reinforcement learning, autonomous driving, and why a written reward is evidence rather than law.AgentsRoboticsReinforcement Learning+3
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Lex Fridman· 26 févr. 2020Podcast · 2 voixWhy Marcus Hutter Treats Compression as Intelligence ItselfInvité : Marcus Hutter · Anime : Lex FridmanThe DeepMind researcher behind AIXI tells Lex Fridman why a Wikipedia compression contest, Solomonoff induction, and an incomputable formula belong in the same conversation.AgentsAGIAI research+3
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