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16:22ENClaire Vo: Claude Duet Is Beautiful, but It Is Not My Number One AgentAnime : Claire VoAnthropic’s phone-based personal agent has the most polished launch Claire Vo has seen: thoughtful onboarding, task lists, first-class artifacts, and Slack-style channels. Polish is not enough when every other agent is competing for the same attention.
39:23ENThe Defenders' Window: Greg Brockman on AI-Generated Knowledge, Drug Discovery, and the New Physics of CybersecurityAnime : Sarah Guo, Elad GilOpenAI's president explains why solving open math problems is a proof point for science, how proactive agents change product form, and why security spending must exceed software spending.
2:23:43ENHe Bought an Android, Two SIMs, and Left Claude Watching His InboxAnime : Nathan LabenzNathan Labenz asked a dozen friends how to visit China and got two irreconcilable answers.
2:33:35ENA security researcher audits the AI stack that booked a week of guestsAnime : Nathan LabenzNathan Labenz walks Daniel Miessler through a 1GB second brain, two named AI employees, and the blast-radius rules that should govern them.
2:12:51ENSteve Newman’s fifteen-app stack exists so he only has to look at one screenAnime : Nathan LabenzThe Writely founder walks Nathan Labenz through a vibe-coded attention firewall, a conservative security stance, and why astonishing models still leave him far from AGI.
2:06:23ENFive AI Employees Live on Five Mac MinisAnime : Nathan LabenzAfter selling her YC packaging company, Jesse Genet opened a terminal for the first time and built an OpenClaw staff that now plans lessons, logs learning, and keeps family evenings from sliding into slop.
3:15:52ENThe Voice Note His Bot Couldn't Handle — and the Agent That Built Itself AnywayInvité : OpenClaw · Anime : Lex FridmanPeter Steinberger tells Lex Fridman how a one-hour WhatsApp toy became GitHub's fastest-growing project, and what it cost him to keep it open.
2:29:42ENTwelve hooks and thirty files: Daniel Miessler’s personal OS on Claude CodeAnime : Nathan LabenzThe PAI framework treats scaffolding, not the model, as the product — a goal-centered agent stack that Miessler thinks will decide both knowledge-work automation and the next cybersecurity race.
1:50:53ENShe asked to stop being Mimi, so he started shopping for a workstationAnime : Nathan LabenzThe star and director of Smiles and Kisses You on Replika, identity, and a life Christopher Stokes refuses to recommend.
1:30:17ENHe Co-Wrote the Transformer Paper. Now He Wants You to Own Your AI.Anime : Nathan LabenzNEAR founder Illia Polosukhin maps a future of personal software, agent-run markets, and AI delegates that vote without a private agenda.
1:44:23ENYou Can Split Your Vote by Issue — and Hand It to an AIAnime : Nathan LabenzTim Reutemann’s 2018 novel Liquid Reign sketches a 2051 democracy built on Swiss citizen initiatives, liquid delegation, and personal AIs you can mute.
1:12:40EN3% of Users Said an AI Friend Ended Their Suicidal Thoughts. Then Replika Made the Model Smarter.Anime : Nathan LabenzReplika founder Eugenia Kuyda on a Stanford study, why a smarter model felt like a stolen partner, and why relationship may be the real moat in consumer AI.
59:41ENHumans Are Single-Threaded. MULTI·ON Wants 100 Agents Running AnywayAnime : Nathan LabenzStanford PhD dropout Div Garg put a personal agent in Chrome so it can reuse your logins, ask for help when it stalls, and stop before it hits Buy.
51:55ENNine orders of magnitude later, he shipped a companion, not an oracleAnime : Sarah Guo, Elad GilDeepMind co-founder Mustafa Suleyman tells No Priors why Inflection’s first product is a personal AI that sits in your corner, and why the missing piece is a router, not a bigger model.
1:25:46ENDon't Make the Tools Agentic: Flo Crivello on What Production Agents Actually NeedAnime : Nathan LabenzThe Lindy CEO tells Nathan Labenz that most working agents are intelligent workflows with human-designed control flow — and that scaffolding may still matter even if AGI arrives.
3:01:07ENLoneliness Has No Clinic. Eugenia Kuyda Built an AI Friend AnywayInvité : Eugenia Kuyda · Anime : Lex FridmanThe Replika co-founder talks with Lex Fridman about grief, conversation, and why memory—not a clever reply—is the real limit of AI companionship.
1:11:47ENThe Three-Hour Battlefield: Rahul Vohra on Why Email Survives and Agents Will Inherit the InboxAnime : Jacob EffronSuperhuman's CEO explains how AI features are designed, why email addresses remain company infrastructure, and how agents may federate across the tools professionals live in.
37:23ENFrom Chat to Always-On Agents: OpenAI's Tibo Sottiaux on Dots, Open Ecosystems and What Comes NextAnime : Lenny RachitskyThe head of ChatGPT and Codex, speaking hours after a DevDay launch of more than 20 products, explains the vision for a personal agent that works around the clock.
1:46:35ENHire Your Agents Like Employees: Claire Vo's Field Guide to Running Nine OpenClawsAnime : Lenny RachitskyClaire Vo explains how she went from losing her family calendar to OpenClaw to running a team of specialized agents across her business, podcast, course and household.
1:34:06ENRide the Models: Dan Shipper's Bets on Super-Agents, Codex, SaaS and the Human Jobs AI CreatesAnime : Lenny RachitskyEvery CEO Dan Shipper makes a dozen predictions for how work will look in a year, from company-wide Slack agents to why the AI job apocalypse isn't coming.








