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16 articlesTrier
21:52ENJosef Witt-Doerring on Gen Z Mental Health, Isolation, and Psychiatric PrescribingShabbos Kestenbaum, Josef Witt-Doerring, Scott Galloway · PragerUOn The Brief, Shabbos Kestenbaum and psychiatrist Josef Witt-Doerring discuss why young adults are struggling, how prescribing incentives shape care, and the place of relationships and daily habits in treatment.
3:36:56ENPsychiatry Has Never Found Its PenicillinAnime : Lex FridmanHistorian Andrew Scull tells Lex Fridman why the field can ease symptoms, has never cured a major mental illness, and keeps paying for overconfidence with patients' lives.
1:19:05ENAI Compute Deals, Cerebras’s IPO and the Cost of Building: A 20VC RoundtableInvité : Jason Lemkin, Rory O’Driscoll · Anime : Harry StebbingsJason Lemkin and Rory O’Driscoll debate AI infrastructure, software competition and IPO valuations, then discuss the personal demands of founding a company.
10:09ENMatthew Berman on Emotional Attachment to AI After GPT-5’s LaunchMatthew Berman · Forward FutureThe 2025 GPT-5 rollout prompted debate about attachment to older models, sycophancy and the effects of AI companionship.
2:19:08ENOliver Anthony sang the pain of working America, then refused the machineInvité : Oliver Anthony · Anime : Lex FridmanLex Fridman sits with the Virginia singer-songwriter whose carport hit became a working-class anthem, and who still treats fame as a test of integrity rather than a prize.
1:09:44ENKevin Hartz on Airbnb, Holding Winners and the Tradeoffs of Venture InvestingInvité : Kevin Hartz · Anime : Harry StebbingsThe A* co-founder discusses an exploding term sheet, fund liquidity, founder selection and why he prefers to hold exceptional companies.
53:24ENPedro Franceschi on Brex’s Product Focus, Leadership and IPO ReadinessInvité : Pedro Franceschi · Anime : Harry StebbingsThe Brex CEO discusses founder mental health, enterprise customers, financial infrastructure and building a more predictable business.
1:16:41ENMario Schlosser on Oscar Health, Public Markets and LeadershipInvité : Mario Schlosser · Anime : Harry StebbingsThe Oscar co-founder reflects on a sharp stock decline, seeking support and handing the CEO role to a successor.
1:16:00ENChristian Lanng on Founder Burnout, Investor Relationships and AI at WorkInvité : Christian Lanng · Anime : Harry StebbingsThe former Tradeshift CEO reflects on a medical emergency, the cost of persistence and his vision for a new AI venture.
2:12:22ENIf It Is Not a Hundred Percent, It Is Not Happening: Huberman on Loyalty, Covert Contracts, and LoveInvité : Andrew Huberman · Anime : Lex FridmanOn Lex Fridman's birthday, Andrew Huberman flew to Austin for dinner, talked into the night, and they recorded a last-minute podcast about the body, the shadow, betrayal, sex, and peace.
1:42:20ENScooter Braun on Success, Vulnerability and Finding Time for FamilyInvité : Scooter Braun · Anime : Harry StebbingsThe music executive and investor reflects on achievement, public identity and the personal work he began after a difficult period in his life.
1:42:06ENJonathan Haidt: Instagram Is Not 'Generally Positive' for Teen MindsInvité : Jonathan Haidt · Anime : Lex FridmanThe NYU social psychologist answers Mark Zuckerberg on adolescent mental health and argues that one business model rewired childhood and then the public square.
2:12:00ENWhen the Plane Went Down, Dan Reynolds Felt NothingInvité : Dan Reynolds · Anime : Lex FridmanThe Imagine Dragons frontman talks with Lex Fridman about C#, ayahuasca, the trap of fame, and the pop prison he built thinking it was a mansion.
3:21:29ENWhen something in the mind breaks, you see what it was forInvité : Karl Deisseroth · Anime : Lex FridmanStanford psychiatrist Karl Deisseroth talks with Lex Fridman about depression, schizophrenia, optogenetics, and why you can treat one symptom without a theory of everything.
1:26:32ENThe Achiever's Trap: A Growth Leader on Burnout, Healing and Letting the Old Self GoInvité : Andy Johns · Anime : Lenny RachitskyFormer Facebook, Twitter and Wealthfront growth leader Andy Johns explains how achievement became his survival strategy, why it broke down, and the four steps he sees in deep personal change.
1:09:51ENPick Channels Like an Improviser: Adam Grenier on New Acquisition Bets, Growth CMOs and BurnoutInvité : Adam Grenier · Anime : Lenny RachitskyFormer Uber and Masterclass marketer Adam Grenier explains how to decide whether an emerging channel deserves your time, what a Growth CMO is, and how to tell burnout from depression.









