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38:14ENDiffusion Will Win Inference: Stefano Ermon Bets Parallel Tokens Beat Custom SiliconAnime : Sarah Guo, Elad GilThe Stanford diffusion pioneer tells No Priors why a 50-person lab is training language models that generate many tokens at once — and why that maps to GPUs the way transformers once mapped to training.
36:58ENSTaR's Author Wants Models With EQ, Not Just More IQAnime : Sarah Guo, Elad GilEric Zelikman, the Stanford and xAI researcher behind STaR and Quiet-STaR, launches humans& on the bet that three years of IQ scaling left models emotionally unintelligent.
38:10ENo3 should wait exactly as long as the answer takesAnime : Sarah Guo, Elad GilOpenAI researchers Eric Mitchell and Brandon McKinzie tell No Priors why o3's leap is a chain of tools during reasoning — and why you should send the same prompt a hundred times.
35:14ENRobots Have No Wikipedia. Chelsea Finn Is Starting With Three Buildings.Anime : Sarah Guo, Elad GilPhysical Intelligence’s cofounder tells No Priors why a generalist robot model has to be trained across embodiments, why open-sourcing hardware is a bet against the problem going unsolved, and why humanoids are a little overrated.
57:41ENA Hundred Million Cells, Four People, Three Days: Biology's ImageNet MomentAnime : Sarah Guo, Elad GilVevo Therapeutics and the Arc Institute open-sourced Tahoe-100M and a 230-million-cell atlas in the same week — and argued that virtual cells, not just protein folders, are the next language model of biology.
2:49:35ZH潘嘉怡解读 R1、o1 与 Kimi K1.5:强化学习如何教模型学会推理Invité : 潘嘉怡 · Anime : 张小珺伯克利博士生潘嘉怡带读 DeepSeek、OpenAI 与 Kimi 的推理模型报告,拆解长思维链、GRPO、奖励设计与蒸馏。R1-Zero 的“顿悟时刻”展示了推理策略如何在强化学习中涌现。
5:15:00ENDario Amodei Has Seen This Scaling Movie Enough TimesInvité : Dario Amodei · Anime : Lex FridmanAnthropic’s CEO puts numbers on frontier training costs and AGI, then hands the mic to the people who shape Claude’s character and look inside its weights.
46:09ENOriol Vinyals: The Days of Burning 90% of Compute on Pretraining Are NumberedAnime : Sarah Guo, Elad GilGoogle DeepMind’s VP of research on Gemini, long context, the coming shift from pretraining to RL, and why AGI may never have a finish line.
34:09ENFive Independent Teams Found the Same 10-to-1 Mix That Beats TransformersAnime : Sarah Guo, Elad GilThe authors of S4 and Mamba argue that mostly state-space layers plus a dash of attention is the architecture that actually works—and they are shipping it first as real-time speech.
2:47:17ENIf You Want Human-Level AI, Abandon Generative ModelsInvité : Yann Lecun · Anime : Lex FridmanYann LeCun tells Lex Fridman why autoregressive LLMs cannot plan, remember, or understand the physical world — and why open source is the only democratic answer.
40:58EN99% of Factory Robots Are Dumb. Covariant Wants the Smart Ones Working in Warehouses FirstAnime : Sarah Guo, Elad GilFormer OpenAI researcher Peter Chen explains why robot foundation models have to be trained on production floors, not in labs.
41:58ENReliability is the bottleneck. Autonomy is what would make AI feel alive.Anime : Sarah Guo, Elad GilIlya Sutskever talks with Sarah Guo and Elad Gil about AlexNet, OpenAI’s capped-profit bet, why smaller models mainly lose reliability, and the line he draws for digital life.
37:01ENDNA Is Code, but You Compile It with a PipetteAnime : Sarah Guo, Elad GilGinkgo Bioworks CEO Jason Kelly tells No Priors why cells are worth the magic, why biology has no AWS, and why a pandemic should look like cybersecurity.
35:24ENThe Author of Attention Is All You Need Now Compiles mRNA Like BytecodeAnime : Sarah Guo, Elad GilJakob Uszkoreit on why Transformers won, why models spend compute on the wrong things, and why drug discovery has to become generation rather than screening.
42:18ENTen Percent of Search Is Health — and the Doctor Is Googling TooAnime : Sarah Guo, Elad GilGoogle researcher Karan Singhal on Med-PaLM 2, the real bar for medical language models, and why medicine is a harder alignment lab than chatbots.
4:14:33ENThe Next Token Is Not a Proof: Stephen Wolfram on ChatGPT and Computational TruthInvité : Stephen Wolfram · Anime : Lex FridmanIn his fourth conversation with Lex Fridman, Stephen Wolfram contrasts large language models with Wolfram|Alpha, then follows computational irreducibility from ChatGPT through observers, thermodynamics, and the three great theories of twentieth-century physics.
40:25ENA 6-Billion-Parameter Clone of ChatGPT’s Core TrickAnime : Sarah Guo, Elad GilDatabricks CTO Matei Zaharia tells Sarah Guo and Elad Gil how Dolly learned instruction-following on fifty times less data than GPT-3 — and why he would rather look facts up than bake them into a trillion-parameter network.
3:28:47ENKarpathy Calls Trained Neural Nets Complicated Alien ArtifactsInvité : Andrej Karpathy · Anime : Lex FridmanOn Lex Fridman's podcast, Andrej Karpathy refuses the brain analogy, walks the Fermi paradox through Nick Lane's chemistry, and treats the Transformer as a general-purpose differentiable computer.
2:10:08ENGato Is Only the BeginningInvité : Oriol Vinyals · Anime : Lex FridmanDeepMind's Oriol Vinyals talks with Lex Fridman about generalist agents, thrown-away weights, and whether human-level AGI arrives in his lifetime.
2:10:39ENDemis Hassabis: Solve Intelligence, Then Solve Everything ElseInvité : Demis Hassabis · Anime : Lex FridmanThe DeepMind CEO tells Lex Fridman why the Turing Test is the wrong exam, how AlphaFold rewrote biology, and why the quiet radio sky suggests we are probably alone.
2:45:10ENA Teenager Learns to Drive in Twenty Hours. A Car Still Cannot.Invité : Yann Lecun · Anime : Lex FridmanYann LeCun tells Lex Fridman why self-supervised world models are the missing dark matter of intelligence, and why machines are not even at the level of a house cat.
2:31:57ENJay McClelland on How Thought Emerges From Neural NetworksInvité : Jay McClelland · Anime : Lex FridmanThe Stanford cognitive scientist talks with Lex Fridman about connectionism, backpropagation, David Rumelhart, and why intuition discovers what logic later proves.
2:51:33ENThe Self Is a GPT Prompt: Wojciech Zaremba on Consciousness, Codex, and Fermi's SilenceInvité : Wojciech Zaremba · Anime : Lex FridmanOpenAI co-founder Wojciech Zaremba tells Lex Fridman he thinks we might be alone in the universe — and that GPT-3, Codex, and a one-handed robot already hint at how intelligence is built.
2:18:29ENYour Cortex Is 150,000 Brains Voting on a Coffee CupInvité : Jeff Hawkins · Anime : Lex FridmanJeff Hawkins tells Lex Fridman that intelligence is learning a model of the world, the neocortex is tens of thousands of independent maps that vote, and the fastest path to machine intelligence is reverse-engineering that sheet.
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