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41:25ENEven If the Models Froze Today, We've Extracted One-Millionth of the ValueAnime : Sarah Guo, Elad GilAirtable CEO Howie Liu on why a 2012 vision deck still maps the company, why enterprise AI is stuck on imagination, and why codegen will not kill no-code before AGI.
51:36ENKlarna's AI Took 700 Customer-Service Jobs. The Secret Was the ManualCEO Sebastian Siemiatkowski tells Sequoia how an OpenAI guinea-pig bet, a dispute-queue Slack message, and documentation written for an amnesiac employee produced $40 million of profit.
2:00:03ENPatients Rated GPT-4 More Empathetic Than DoctorsAnime : Nathan LabenzAzeem Azhar of Exponential View maps the AI S-curve for Nathan Labenz: why the past always looks flat, why empathy went first, and what a million times more compute would actually change.
1:50:57ENTwenty-Eight Days After GPT-4, an AI Designed and Ran a Chemistry ExperimentAnime : Nathan LabenzGabe Gomes and his Carnegie Mellon students built Coscientist, a language-model agent that plans, codes, and executes real experiments on a remote cloud lab.
1:18:39ENThe GPT-4 Red-Teamer Who Got Unstuck by a Mediocre OutlineAnime : Nathan LabenzDan Shipper shows Nathan Labenz how to use ChatGPT as a copilot for thinking, not as a ghostwriter for his own voice.
1:30:21ENA Million DALL-E Images, Distilled into Twelve Minutes of FilmAnime : Nathan LabenzWaymark’s Stephen Parker and Josh Rubin walk through how they turned stills from DALL-E 2 into The Frost, a narrative short, and what the next generation of video models changes.
39:02ENAI’s product advantage is consistency. Its real weakness is getting conned.Anime : Nathan LabenzNathan Labenz updates the Cognitive Revolution scouting report: jailbreaks, resume automation, Med-PaLM’s 40% radiology win, and what might follow Transformers.
1:30:29ENGPT-4 Wins Ten Times More Bill Fights: DoNotPay's Robot-Lawyer WarAnime : Nathan LabenzGPT-3 thanked Comcast for twenty dollars off. GPT-4 said that was not enough — and the robot lawyer called it an arms race.
1:10:11ENTrying ChatGPT is not the same as using itAnime : Nathan LabenzRachel Woods of The AI Exchange tells Nathan Labenz what she learned from more than a hundred company calls: start inside the business, skip the annual tool contract, and expect to be using only a sliver of what the models can already do.
58:26ENSeventy Percent of the Inbox Is a Pitch: Matt Welsh on the First Wave of AI AgentsAnime : Nathan LabenzThe Fixie.ai founder maps copilot versus delegation, the missing appendages into our systems, and why agents will need guardrails, memory hygiene, and probably an earpiece.
1:25:46ENDon't Make the Tools Agentic: Flo Crivello on What Production Agents Actually NeedAnime : Nathan LabenzThe Lindy CEO tells Nathan Labenz that most working agents are intelligent workflows with human-designed control flow — and that scaffolding may still matter even if AGI arrives.
1:34:57ENFifteen People, Four Products, Zero Handwritten Code: Inside Every's AI-First CompanyInvité : Dan Shipper · Anime : Lenny RachitskyEvery CEO Dan Shipper explains how his small team uses Claude Code, an AI operations lead and compounding engineering to do the work of a much larger company.
1:11:47ENThe Three-Hour Battlefield: Rahul Vohra on Why Email Survives and Agents Will Inherit the InboxAnime : Jacob EffronSuperhuman's CEO explains how AI features are designed, why email addresses remain company infrastructure, and how agents may federate across the tools professionals live in.
19:31ENBuild the Factory, Not Just the Product: How Ramp Chases Bottlenecks Across the Whole Development LoopAnime : Lenny RachitskyRamp CPO Geoff Charles walks through the AI agents his team built for every stage of product development, and what they mean for the PM's role.
1:28:28ENFish Where the Fish Are: Andrew Wilkinson on Boring Businesses, AI Agents and Why Money Didn't Make Him HappyInvité : Andrew Wilkinson · Anime : Lenny RachitskyThe co-founder of Tiny, the "Berkshire Hathaway of the internet", explains how to pick a startup idea, how he runs his life on AI agents, and what actually changed his happiness.
1:04:35ENOscar Health's AI Playbook: Translate the Bureaucracy First, Then Reinvent CareAnime : Jacob EffronMario, Oscar Health's CTO and co-founder, explains how a regulated insurer deploys LLMs today and what stands between healthcare and AI doctors.
1:46:35ENHire Your Agents Like Employees: Claire Vo's Field Guide to Running Nine OpenClawsAnime : Lenny RachitskyClaire Vo explains how she went from losing her family calendar to OpenClaw to running a team of specialized agents across her business, podcast, course and household.
17:32ENOver-Automating, Googling Doctors and Neural Nets: George Hotz Reviews Programming MemesAnime : Lex FridmanLex Fridman and George Hotz rate printed programming memes, and the jokes turn into candid talk about testing, hiring, social media and the power of neural networks.









