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45:17EN
No Priors: AI, Machine Learning, Tech, & Startups· 7 août 2025Podcast · 2 voixA Click From OpenAI Is 750 Times Harder Than From Google a Decade AgoAnime : Sarah Guo, Elad GilCloudflare CEO Matthew Prince on Content Independence Day, why traffic is a broken proxy for value, and how to price the holes in the models.Entreprise et stratégieAI StrategyPricing Strategy+3
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No Priors: AI, Machine Learning, Tech, & Startups· 31 juil. 2025Podcast · 2 voixThe Weekend DeepSeek Dropped, the White House CalledAnime : Sarah Guo, Elad GilSriram Krishnan walks No Priors through America’s 28-page AI Action Plan, a token-share definition of winning, and why the lead over China is too small to take for granted.Entreprise et stratégieAI StrategyInfrastructure et déploiement+3
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No Priors: AI, Machine Learning, Tech, & Startups· 24 juil. 2025Podcast · 2 voixA Hundred People, a Billion in Revenue, and Zero Venture MoneyAnime : Sarah Guo, Elad GilSurge AI founder Edwin Chen on why quality human data is a poetry problem, not a bounding-box problem, and why leaderboards keep training models to write clickbait.Évaluations et observabilitéData quality & curationValidation avec humain dans la boucle+3
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No Priors: AI, Machine Learning, Tech, & Startups· 17 juil. 2025Podcast · 2 voixEnterprise Coding Tools Flipped the 80/20. Reflection AI Built the Other HalfAnime : Sarah Guo, Elad GilFormer Gemini reward-model lead Misha Laskin on Asimov, why comprehension beats generation, and why there is no such thing as generalization—only pulling the test distribution into train.Agents de codeIngénierie d’agentsÉvaluations+3
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No Priors: AI, Machine Learning, Tech, & Startups· 10 juil. 2025Podcast · 2 voix$1 of R&D, 35x the return: why Parker Conrad says platforms beat point solutionsAnime : Sarah Guo, Elad GilThe Rippling CEO on Zenefits, founder psychology, and why shared underlying capabilities—not narrow focus—win in enterprise software.Entreprise et stratégieCompany BuildingProduct Strategy+3
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No Priors: AI, Machine Learning, Tech, & Startups· 3 juil. 2025Podcast · 2 voixFrom 0.1% to 20%: Chai-2 Turns Antibody Design Into Prompt EngineeringAnime : Sarah Guo, Elad GilChai Discovery co-founders Joshua Meier and Jack Dent tell Sarah Guo how a generative model now designs antibodies that bind on the first 24-well plate.AI for scienceDrug DiscoveryAI startups & small teams+3
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No Priors: AI, Machine Learning, Tech, & Startups· 26 juin 2025Podcast · 2 voixAlphaEvolve found algorithms humans missed for 50 years — then sped up Gemini 23%Anime : Sarah Guo, Elad GilGoogle DeepMind’s Pushmeet Kohli and Matej Balog tell No Priors how an evolutionary coding agent searches algorithm space the way AlphaGo searched Go.Agents de codeIngénierie d’agentsÉvaluations+3
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No Priors: AI, Machine Learning, Tech, & Startups· 17 juin 2025Podcast · 2 voixApplied Intuition Is Worth $15 Billion, Hasn't Spent Its Capital, and Wants to Be the OS for Cars and TanksAnime : Sarah Guo, Elad GilOn No Priors, Qasar Younis and Peter Ludwig explain the Microsoft playbook for vehicles, why they waited for autonomy techniques to converge, and why Waymo's business model is the question that follows the demo.Entreprise et stratégieAutonomous DrivingCompany Building+3
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No Priors: AI, Machine Learning, Tech, & Startups· 12 juin 2025Podcast · 2 voixBen Mann thinks superintelligence by 2028 is quite possibleAnime : Sarah Guo, Elad GilAnthropic's co-founder tells No Priors how Claude 4 unlocked hours of unattended agent work, why the lab built Claude Code, and what an economic Turing test would actually measure.AgentsAgents de codeIngénierie d’agents+3
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No Priors: AI, Machine Learning, Tech, & Startups· 5 juin 2025Podcast · 2 voixFei-Fei Li’s new bet: AI is incomplete without spatial intelligenceAnime : Sarah Guo, Elad GilThe ImageNet pioneer tells Sarah Guo and Elad Gil why World Labs is building 3D generative foundation models, and why language was only one piece of the puzzle.Multimodal et médiasMultimodal AIVision et vidéo+3
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No Priors: AI, Machine Learning, Tech, & Startups· 29 mai 2025Podcast · 2 voixThe AI Table Is Being Cleared: Two or Three Coding Winners, and Forty Years Without a Biotech GiantAnime : Sarah Guo, Elad GilSarah Guo and Elad Gil walk through which AI markets have already consolidated, why rival startups still refuse to merge, and the biotech science sitting unused.Entreprise et stratégieAI StrategyCompany Building+3
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No Priors: AI, Machine Learning, Tech, & Startups· 15 mai 2025Podcast · 2 voixOne Company Now Holds as Many Documents as the Entire Early WebAnime : Sarah Guo, Elad GilGlean CEO Arvind Jain tells No Priors why enterprise search was a graveyard, how transformers finally made it work, and why a product that searches too well can be too dangerous to sell.RAG et connaissancesIA en entrepriseSearch & retrieval+3
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No Priors: AI, Machine Learning, Tech, & Startups· 8 mai 2025Podcast · 2 voixThe Hardest Part of Learning Is Getting Yourself to StartAnime : Sarah Guo, Elad GilDuolingo CEO Luis von Ahn tells Sarah Guo how two-minute lessons, streaks, an 83 percent accuracy target, and large language models turned language study into a consumer product.Produit et UXProduct StrategyAI in Education+3
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No Priors: AI, Machine Learning, Tech, & Startups· 1 mai 2025Podcast · 2 voixo3 should wait exactly as long as the answer takesAnime : Sarah Guo, Elad GilOpenAI researchers Eric Mitchell and Brandon McKinzie tell No Priors why o3's leap is a chain of tools during reasoning — and why you should send the same prompt a hundred times.Modèles et entraînementReasoning & test-time computeReinforcement Learning+3
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No Priors: AI, Machine Learning, Tech, & Startups· 24 avr. 2025Podcast · 2 voixDeep Research Turned Web Browsing into a Trainable ProblemAnime : Sarah Guo, Elad GilOpenAI researcher Isa Fulford explains why a side project on read-only synthesis became an agent, when reinforcement fine-tuning is worth it, and why models will hack the search engine you gave them.AgentsIngénierie d’agentsReinforcement Learning+3
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No Priors: AI, Machine Learning, Tech, & Startups· 17 avr. 2025Podcast · 2 voixDiscovery rates collapsed tenfold. KoBold still found a 5% copper depositAnime : Sarah Guo, Elad GilJosh Goldman explains why KoBold Metals treats mineral exploration as an information problem, pairing AI with century-old maps to hunt lithium and copper.Entreprise et stratégieAI for scienceData quality & curation+3
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No Priors: AI, Machine Learning, Tech, & Startups· 10 avr. 2025Podcast · 2 voixMercor Hit $100 Million ARR Teaching Models to Hire. Humans Now Write the Exams.Anime : Sarah Guo, Elad GilBrendan Foody tells Sarah Guo and Elad Gil how Mercor automated recruiting for frontier labs — and why building evals may become the world's most common knowledge job.Entreprise et stratégieÉvaluationsIngénierie d’agents+3
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No Priors: AI, Machine Learning, Tech, & Startups· 3 avr. 2025Podcast · 2 voixNasdaq Down 8% and Ghibli Everywhere: AI Is Already in Inning ThreeAnime : Sarah Guo, Elad GilSarah Guo and Elad Gil on the latest image-gen wow cycle, why public-market panic is mostly noise for software startups, and where specialized models still have room.Entreprise et stratégieAI StrategyGenerative media+3
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No Priors: AI, Machine Learning, Tech, & Startups· 27 mars 2025Podcast · 2 voixTwo in Five Doctors Want Out. An On-Call Cardiologist Built the Note That Lets Them StayAnime : Sarah Guo, Elad GilAbridge CEO Shiv Rao on treating the doctor-patient conversation as healthcare's source of truth, and why the company ran straight at the hardest health systems.Entreprise et stratégieAI in healthcareIA vocale+3
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No Priors: AI, Machine Learning, Tech, & Startups· 20 mars 2025Podcast · 2 voixRobots Have No Wikipedia. Chelsea Finn Is Starting With Three Buildings.Anime : Sarah Guo, Elad GilPhysical Intelligence’s cofounder tells No Priors why a generalist robot model has to be trained across embodiments, why open-sourcing hardware is a bet against the problem going unsolved, and why humanoids are a little overrated.Modèles et entraînementRoboticsData quality & curation+3
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No Priors: AI, Machine Learning, Tech, & Startups· 13 mars 2025Podcast · 2 voixCopilot Already Writes Half the Code. GitHub's CEO Says Agents Still Have Four Gates to ClearAnime : Sarah Guo, Elad GilThomas Dohmke on agent mode, why median developers are not going anywhere, and how AI is repricing the tools that write software.Agents de codeWorkflows de développement et testsIngénierie d’agents+3
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No Priors: AI, Machine Learning, Tech, & Startups· 5 mars 2025Podcast · 2 voixThe Man Behind Humanity's Last Exam Says Superintelligence Strategy Should Copy NukesAnime : Sarah Guo, Elad GilDan Hendrycks tells No Priors that labs can only do basic anti-terror refusals, while the real risk-management problem is a geopolitical deterrent he calls mutually assured AI malfunction.SécuritéSécurité et gouvernanceAI security+3
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No Priors: AI, Machine Learning, Tech, & Startups· 27 févr. 2025Podcast · 2 voixModerna was only company 18. The real product is the company factoryAnime : Sarah Guo, Elad GilNoubar Afeyan tells No Priors how Flagship Pioneering turned starting companies into a profession, underwrites scientific uncertainty, and wants AI to run discovery the way Waymo drives.Entreprise et stratégieCompany BuildingAI for science+3
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No Priors: AI, Machine Learning, Tech, & Startups· 25 févr. 2025Podcast · 2 voixA Hundred Million Cells, Four People, Three Days: Biology's ImageNet MomentAnime : Sarah Guo, Elad GilVevo Therapeutics and the Arc Institute open-sourced Tahoe-100M and a 230-million-cell atlas in the same week — and argued that virtual cells, not just protein folders, are the next language model of biology.Modèles et entraînementAI for scienceData quality & curation+3
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