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Cognitive Revolution "How AI Changes Everything"· 14 oct 2025Pódcast2,500 Compounds and a 51 Percent Hit Rate: How a Small Graph Net Found New AntibioticsPresenta: Nathan LabenzMIT's Jim Collins tells Nathan Labenz how a bootlegged 2018 project, a binary growth-inhibition label, and Chemprop graph networks pulled novel antibiotics out of chemical space that labs could never screen by hand.
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No Priors: AI, Machine Learning, Tech, & Startups· 9 oct 2025Pódcast · 2 vocesSTaR's Author Wants Models With EQ, Not Just More IQPresenta: Sarah Guo, Elad GilEric Zelikman, the Stanford and xAI researcher behind STaR and Quiet-STaR, launches humans& on the bet that three years of IQ scaling left models emotionally unintelligent.
1:01:49ENCognitive Revolution "How AI Changes Everything"· 2 oct 2025PódcastChatGPT's Co-Creator Left to Put Nature in the Reward LoopPresenta: Nathan LabenzLiam Fedus and Ekin Dogus Cubuk on why language models still fail at physics, why literature data is too noisy to train on, and why Periodic Labs is aiming at a 200K superconductor.
1:22:07ENCognitive Revolution "How AI Changes Everything"· 25 sept 2025PódcastEvery payment is a frame in a movie. Stripe’s foundation model took card-testing detection from 59% to 97%Presenta: Nathan LabenzEmily Sands, Stripe’s head of data and AI, explains how a domain-specific payments model, shared embeddings, and mixed rules turn a $1.4 trillion network into compounding advantage.
2:02:17ENCognitive Revolution "How AI Changes Everything"· 27 ago 2025PódcastSAEs Find the Nouns. Parameter Decomposition Looks for the VerbsPresenta: Nathan LabenzGoodfire's Lee Sharkey argues that sparse autoencoders recover a network's variables, not the algorithms those variables run, and shows how stochastic parameter decomposition tries to recover the computations themselves.
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3Blue1Brown· 17 ago 2025How AlphaGeometry Combines Logical Proof with Creative ConstructionAleph0Aleph0 explains how a symbolic geometry solver gets surprisingly far without AI, and how a language model supplies the auxiliary constructions that take it to Olympiad level.
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Unsupervised Learning: With Jacob Effron· 13 ago 2025PódcastThey Aimed for 1%. The Lab Hit 20%. Chai Discovery Moved Antibody Design Onto the Computer.Presenta: Jacob EffronJoshua Meier on three waves of AI drug discovery, why Chai-2 behaves like Photoshop for molecules, and why a 1% hit rate was supposed to be enough to change the industry.
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Sequoia Capital· 30 jul 2025PódcastFrom 12 Percent on AIME to IMO Gold in Two MonthsAlex Wei, Sheryl Hsu, and Noam Brown tell Sequoia's Sonya Huang how a three-person OpenAI sprint used general-purpose reinforcement learning, not Lean, to reach gold-level on the 2025 International Mathematical Olympiad.
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跟李沐学AI· 23 jul 2025李沐：给文本大模型加入一千万小时语音，开源 Higgs Audio李沐 · Boson AI李沐介绍团队如何在文本大语言模型的训练里加入大量语音数据，做成能听能说的 AudioLLM，并把 Higgs Audio 开源。他讲了架构取舍、token 压缩、数据从哪来，以及怎么在 3090 上跑起来。
38:10ENCognitive Revolution "How AI Changes Everything"· 16 jul 2025PódcastPlus Five for Format, Plus Ten if It CompilesPresenta: Nathan LabenzPredibase CEO Dev Rishi explains how reinforcement fine-tuning, production feedback, and narrow specialist models turn one-off training into systems that keep learning.
1:42:06ENCognitive Revolution "How AI Changes Everything"· 8 jul 2025PódcastEvery Frontier Lab Is Spending a Billion a Year on Data. Here Is Where It GoesPresenta: Nathan LabenzLabelbox CEO Manu Sharma on the $15 billion Scale deal, RL “gyms,” $250,000 trainers, and why post-training now eats the budget that used to belong to pre-training.
1:37:05ENCognitive Revolution "How AI Changes Everything"· 19 jun 2025PódcastAn Algebraic Geometer Quit Tenure Because the Bowl-Shaped Loss Plot Is a LiePresenta: Nathan LabenzJesse Hoogland and Daniel Murfet of Timaeus argue that singularities in the loss landscape — not the smooth valleys in every slide deck — are what actually govern how neural networks learn, generalize, and go wrong.
48:51ENSequoia Capital· 17 jun 2025PódcastThe Breakthroughs for AGI Are Already Done, Says OpenAI’s Former Research HeadBob McGrew tells Sequoia’s Training Data that 2025 is the year of reasoning, agents will be priced at the cost of compute, and nothing fundamental will be added to the stack by 2035.
1:54:08ENCognitive Revolution "How AI Changes Everything"· 29 may 2025PódcastWhy Anthropic's first check went to a company building microscopes for neural netsPresenta: Nathan LabenzGoodfire's Dan Balsam and Tom McGrath argue that mechanistic interpretability now has a proto-paradigm, two stubborn gaps, and three products worth shipping today.
2:12:00ENCognitive Revolution "How AI Changes Everything"· 15 may 2025PódcastGradient Descent at Test Time: Titans Pushes LLM Context to 10 Million TokensPresenta: Nathan LabenzA Cornell PhD student's neural memory module holds about 70% accuracy where GPT-4's scores fall off a cliff.
47:00ENUnsupervised Learning: With Jacob Effron· 8 may 2025PódcastAn Eval Lasts Three Months — and a Frozen Frontier Would Still Feed Startups for a DecadePresenta: Jacob EffronOpenAI’s GPT-4.1 post-training lead Michelle Pokrass tells Unsupervised Learning how the team spent three months on evals before training, why agents fail on wiring more than intelligence, and when to reach for RFT.
38:10ENNo Priors: AI, Machine Learning, Tech, & Startups· 1 may 2025Pódcast · 2 voceso3 should wait exactly as long as the answer takesPresenta: Sarah Guo, Elad GilOpenAI researchers Eric Mitchell and Brandon McKinzie tell No Priors why o3's leap is a chain of tools during reasoning — and why you should send the same prompt a hundred times.
58:11ENSequoia Capital· 15 abr 2025PódcastPatrick Hsu Wants an App Store for Biology, Not Just Better DrugsThe Arc Institute co-founder argues that Evo 2, trained on genomes rather than proteins, should underpin tools for every step of the scientific method.
1:14:11ENCognitive Revolution "How AI Changes Everything"· 5 abr 2025PódcastThe Reasoning Curve Was Smooth All Along: Gemini 2.5's Jack Rae on Thinking, Memory, and AGIPresenta: Nathan LabenzDeepMind's thinking-and-inference lead explains why RL-for-reasoning felt sudden, why Gemini shows raw chain of thought, and why a million-token window still is not memory.
1:43:54ENCognitive Revolution "How AI Changes Everything"· 23 mar 2025PódcastA Year to Grow a Brain Organoid, an Hour to Simulate ItPresenta: Nathan LabenzStanford postdoc Siyu He tells Nathan Labenz how Squidiff and CORAL move single-cell and spatial experiments into the computer — and where the models still cannot go.
35:14ENNo Priors: AI, Machine Learning, Tech, & Startups· 20 mar 2025Pódcast · 2 vocesRobots Have No Wikipedia. Chelsea Finn Is Starting With Three Buildings.Presenta: Sarah Guo, Elad GilPhysical Intelligence’s cofounder tells No Priors why a generalist robot model has to be trained across embodiments, why open-sourcing hardware is a bet against the problem going unsolved, and why humanoids are a little overrated.
1:10:23ENUnsupervised Learning: With Jacob Effron· 17 mar 2025PódcastA Million Tokens per Dollar: Why Noam Shazeer Thinks Inference Compute Is Still UntappedPresenta: Jacob EffronThe Transformer co-inventor and Gemini researcher Jack Rae walk through test-time compute, Ilya Sutskever's AGI critique, and a four-year-old who now lectures his teacher about lizards.
1:56:38ENCognitive Revolution "How AI Changes Everything"· 8 mar 2025Pódcasto3 took ARC from 20% to 87%. Nathan Labenz sketches early superintelligencePresenta: Nathan LabenzOn Consistently Candid, the Cognitive Revolution host argues that math and coding will be superhuman by 2026, and that a reasoning core plus specialist “intuitive physics” may already be enough.
57:41ENNo Priors: AI, Machine Learning, Tech, & Startups· 25 feb 2025Pódcast · 2 vocesA Hundred Million Cells, Four People, Three Days: Biology's ImageNet MomentPresenta: Sarah Guo, Elad GilVevo Therapeutics and the Arc Institute open-sourced Tahoe-100M and a 230-million-cell atlas in the same week — and argued that virtual cells, not just protein folders, are the next language model of biology.Cargar másMostrando 24 de 198