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2:40:18ENEvery Living Cell Runs the Same Translation MachineInvitado: Betül Kaçar · Presenta: Lex FridmanAstrobiologist Betül Kaçar tells Lex Fridman how the tree of life is drawn backward, why nitrogen was fixed only once, and why the genetic code is an alphabet with room for typos.
0:52ENBen Chestnut on His Children Discovering Mailchimp’s SuccessInvitado: Ben ChestnutThe Mailchimp co-founder shares a family anecdote about wealth and an unexpected magazine cover.
3:42:34ENBhaskar Sunkara Will Not Call Forced Collectivization Anything but a DisasterInvitado: Bhaskar Sunkara · Presenta: Lex FridmanThe Jacobin founder and Nation president tells Lex Fridman that democratic socialism starts by refusing the No True Scotsman defense of the twentieth century.
0:43ENBarry McCarthy on Peloton’s Brand and Pandemic GrowthInvitado: Barry McCarthyA 2022 CEO perspective on customer experience and scale.
49:49ENBarry McCarthy on Netflix, Spotify and Leading Peloton’s TurnaroundInvitado: Barry McCarthy · Presenta: Harry StebbingsThe then Peloton CEO reflects on subscription economics, decision ownership and the emotional demands of a turnaround.
2:06:25ENNathalie Cabrol Wants the Nature of Life, Not Just a Signal from MarsInvitado: Nathalie Cabrol · Presenta: Lex FridmanThe SETI Institute astrobiologist tells Lex Fridman why crater lakes, panspermia, and a Mandelbrot view of language all point to the same question: what life actually is.
55:47ZHNeural Corpus Indexer 论文精读:用生成模型检索文档从倒排索引、双塔检索到 NCI 的语义文档 ID,同时讨论数据泄露更正与部署瓶颈。
53:50ENBartosz Milewski: A Taste of Type TheoryBartosz Milewski · Reliable SoftwareFrom recursive natural numbers and dependent vectors to identity types and path induction.
58:18ENHadi Partovi on Leadership, Hiring and Teaching Computer ScienceInvitado: Hadi Partovi · Presenta: Harry StebbingsThe Code.org founder draws on Microsoft, Facebook and startup experience to discuss decision-making, talent and an education system adapting to technology.
1:08:53ENMaggie Hott on Building Enterprise Sales and Hiring the First RepsInvitado: Maggie Hott · Presenta: Harry StebbingsThe Webflow sales leader explains how to combine self-serve adoption with sales, build outbound and evaluate candidates.
3:40:53ENThe White Pill: See How Bad It Got, Then Keep Going AnywayInvitado: Michael Malice · Presenta: Lex FridmanOn a Lex Fridman Christmas special, Michael Malice talks through The White Pill — why 19th-century socialism looked scientific and humane, why violence sings its own song, and why cynics who call themselves realists are lying.
58:38ENBen Chestnut on Building Mailchimp, Selling to Intuit and Finding ContentmentInvitado: Ben Chestnut · Presenta: Harry StebbingsThe Mailchimp co-founder recounts a bootstrapped journey from web design to email marketing, and reflects on leadership, family and life after a sale.
4:05:21ENThe men who trained Mexico's new police later became the ZetasInvitado: Ed Calderon · Presenta: Lex FridmanEd Calderon tells Lex Fridman what counter-narcotics work in Tijuana taught him about corruption, cartels, and why honesty can be a liability.
1:00:49ENBob Pittman on MTV, iHeartMedia and the Discipline of Consumer BusinessesInvitado: Bob Pittman · Presenta: Harry StebbingsThe media executive discusses dissent, fast decisions, convenience and the economics behind radio and podcasts.
0:36ENMarty Cagan on Recruiting With a Compelling VisionInvitado: Marty CaganA short interview excerpt and its context.
3:46:18ENA Ten-Billion-Dollar Error Bar on Other People's MoneyInvitado: Coffeezilla · Presenta: Lex FridmanYouTube investigator Coffeezilla walks Lex Fridman through how Sam Bankman-Fried's FTX turned a low-risk story into a customer-asset casino.
1:07:17ENMarty Cagan on Product Discovery, Hiring and Empowered TeamsInvitado: Marty Cagan · Presenta: Harry StebbingsThe Silicon Valley Product Group founder explains how product teams test risk, learn from customers and develop the skills to own outcomes.
2:29:21ENThe Poker Bot That Never Tried to Read a SoulInvitado: Noam Brown · Presenta: Lex FridmanNoam Brown tells Lex Fridman how a Nash-equilibrium bot crushed heads-up no-limit Hold'em, how Pluribus did it six-handed, and why Diplomacy required an AI that could earn human trust.
1:05:07ENMartin Casado on Building Markets and Rethinking Venture CapitalInvitado: Martin Casado · Presenta: Harry StebbingsThe a16z general partner explains how an engineer became an investor, why founders need patient category-building, and how venture firms might scale.
1:00:19ENWilliam Hockey on Plaid, Column and Building Financial InfrastructureInvitado: William Hockey · Presenta: Harry StebbingsThe Plaid co-founder explains why he started a regulated bank, how he thinks about patient hiring and what he expects from the next decade of fintech.
2:59:33ENRoger Gracie Cleared His Mind, Conserved Every Move, and Refused to Be Number TwoInvitado: Roger Gracie · Presenta: Lex FridmanThe ten-time world champion walks Lex Fridman through the Buchecha rematch, why tapping is intelligence, and how a late-starting chubby kid decided to become the best in the world.
1:16:12ENJason Lemkin on Finding SaaS Investments, Founder Feedback and the Algolia BetInvitado: Jason Lemkin · Presenta: Harry StebbingsThe SaaStr founder revisits an early investment in Algolia and explains how operator experience, honest competitive analysis and difficult conversations shape his venture practice.
2:44:52ENDon't Try to Pen Them In: Todd Howard on Skyrim, Starfield, and Accidental DoorsInvitado: Todd Howard · Presenta: Lex FridmanThe Bethesda Game Studios director on saying yes to players, leaving a test cell full of every weapon, and why Starfield's empty planets are the point.
1:16:00ENMiki Kuusi on Building Wolt, Leading Through Crisis and Joining DoorDashInvitado: Miki Kuusi · Presenta: Harry StebbingsThe Wolt founder discusses focus, hiring, trust, the painful 2017 layoffs and why he chose to combine with DoorDash.
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