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2:31:57ENJay McClelland on How Thought Emerges From Neural NetworksInvitado: Jay McClelland · Presenta: Lex FridmanThe Stanford cognitive scientist talks with Lex Fridman about connectionism, backpropagation, David Rumelhart, and why intuition discovers what logic later proves.
3:12:21ENThe Ape's Brain Runs a Dream: Joscha Bach on Consciousness, Freedom, and MeaningInvitado: Joscha Bach · Presenta: Lex FridmanA long conversation about the self as a control model, the dream world generated by the brain, free will, language models, evil, love, and how to live without a fixed self.
2:48:18ENHumans are the only species that skip sleep on purposeInvitado: Matt Walker · Presenta: Lex FridmanBerkeley sleep scientist Matt Walker talks with Lex Fridman about why we sleep, what caffeine and dreams actually do, and whether passion can justify the health cost of staying up.
2:18:29ENYour Cortex Is 150,000 Brains Voting on a Coffee CupInvitado: Jeff Hawkins · Presenta: Lex FridmanJeff Hawkins tells Lex Fridman that intelligence is learning a model of the world, the neocortex is tens of thousands of independent maps that vote, and the fastest path to machine intelligence is reverse-engineering that sheet.
2:31:30ENThe Brain Is the Last Unengineered System in SocietyInvitado: Bryan Johnson · Presenta: Lex FridmanBryan Johnson demos Kernel Flow on Lex Fridman, then argues that cognition is society's largest unmeasured input and that numbers, not vibes, should run mental health, diet, and the next wave of brain interfaces.
1:56:17ENIf You Reran Earth a Million Times, Would Anything Like Us Appear?Invitado: Risto Miikkulainen · Presenta: Lex FridmanRisto Miikkulainen on neuroevolution, hyena raids, basil that never sleeps, and why variation-plus-selection still finds solutions backpropagation cannot see.
2:58:38ENSleep runs on two clocks — and worrying about it can be worse than a short nightInvitado: Andrew Huberman · Presenta: Lex FridmanStanford neuroscientist Andrew Huberman tells Lex Fridman how adenosine and body temperature decide when you crash, why dreams work like overnight therapy, and what the chemistry of effort has to do with not quitting.
2:14:55ENHis Wife Calls Him the RadioInvitado: Manolis Kellis · Presenta: Lex FridmanMIT computational biologist Manolis Kellis spends the first forty minutes of his fourth Lex Fridman conversation on the songs that formed him, then turns to 42, dinosaurs, and why hunting for meaning matters more than finding it.
2:20:31ENThe Most Romantic Gift Lisa Feldman Barrett Ever Got Was a Six-Way PlugInvitado: Lisa Feldman Barrett · Presenta: Lex FridmanOn her second Lex Fridman Podcast, the neuroscientist traces how she fell in love over a 1992 bulletin board, why brains evolved to hunt rather than to think, and how a body budget can change a mood.
2:35:30ENOn a Perfectly Flat Floor, Heights Still WorkInvitado: Andrew Huberman · Presenta: Lex FridmanStanford neuroscientist Andrew Huberman talks with Lex Fridman about fear circuits, matching inner arousal to outer demand, and why the first minutes after sleep should not belong to someone else's timeline.
2:39:45ENThe obesity gene was never the obesity geneInvitado: Manolis Kellis · Presenta: Lex FridmanManolis Kellis tells Lex Fridman how one nucleotide a million bases from FTO rewrote obesity biology, and why human genetics is now driving the study of disease.
2:23:38ENThe Brain That Never Touches the WorldInvitado: Lisa Feldman Barrett · Presenta: Lex FridmanNeuroscientist Lisa Feldman Barrett tells Lex Fridman why your skull is a dark box, why emotions are constructed like money, and why empathy is a metabolic bill.
2:10:53ENAll Your DNA Would Reach Jupiter a Hundred Times OverInvitado: Manolis Kellis · Presenta: Lex FridmanManolis Kellis talks Lex Fridman through the epigenome, Neanderthals, Europa, midlife, and why "are you happy?" is the wrong question.
1:41:24ENA child can lose half a brain. The rest will rewire around the jobInvitado: David Eagleman · Presenta: Lex FridmanNeuroscientist David Eagleman tells Lex Fridman why the human brain is not hardware running software, but a livewired system that never stops physically reshaping itself.
2:10:06ENYou Might Have to Understand the World to Understand the Letter AInvitado: Dileep George · Presenta: Lex FridmanDileep George on recursive cortical networks, why a five-year-old can read any new CAPTCHA, and what the Wright brothers actually learned from birds.
2:00:32ENSlow Synapses Grow Fast Learners — Warmth Is the Harder ProblemInvitado: Matt Botvinick · Presenta: Lex FridmanDeepMind neuroscience director Matt Botvinick tells Lex Fridman how prefrontal cortex, meta-reinforcement learning, and dopamine research meet the human question of what a better life with AI would actually look like.
45:31ENYou Are Your Own Existence Proof: Karl Friston on Free Energy, Life, and Self-AwarenessPresenta: Lex FridmanKarl Friston explains how the free energy principle reframes existence, life, planning, and self-awareness as inference problems.
1:29:02ENYou Are Your Own Existence ProofInvitado: Karl Friston · Presenta: Lex FridmanKarl Friston walks Lex Fridman from brain imaging to the free energy principle, arguing that anything which keeps a boundary looks as if it is doing Bayesian inference.
1:27:57ENThe Brain's Best Computer Has No Inner LifeInvitado: Roger Penrose · Presenta: Lex FridmanRoger Penrose tells Lex Fridman why HAL raises a moral problem the field will not name, why the cerebellum wrecks the computational theory of mind, and why gravity, Gödel, and an infinite cosmos all hang on the same kind of understanding.
1:12:48ENJohn Hopfield's Physics of Mind: Glitches Become FeaturesInvitado: John Hopfield · Presenta: Lex FridmanThe Princeton physicist walks Lex Fridman from a wobbly London bridge to Hopfield networks, consciousness-as-story, and why his famous model still does not explain learning.
36:10ENSo You're Saying There's a Chance: Musk on Neuralink, AI, and a Pale Blue DotInvitado: Elon Musk · Presenta: Lex FridmanLex Fridman and Elon Musk move from consciousness and an AI referee to the engineering of a brain implant, Tesla Autopilot, and Carl Sagan's lonely speck.
1:01:00ENA Hundred Billion Galaxies, and We're Still a Type 0.7 CivilizationInvitado: Michio Kaku · Presenta: Lex FridmanTheoretical physicist Michio Kaku talks with Lex Fridman about aliens, string theory, digital immortality, and why fusion and Mars are the next civilizational steps.
1:15:58ENHuman Intelligence Is a Ridiculously Narrow SliverInvitado: Yann Lecun · Presenta: Lex FridmanYann LeCun tells Lex Fridman why giant nets plus gradient descent broke the textbooks, why "AGI" is the wrong word, and why the next leap is a world model learned like a baby.
57:42ENA Brain Organoid Is Not a BrainInvitado: Paola Arlotta · Presenta: Lex FridmanHarvard developmental biologist Paola Arlotta on how the cerebral cortex is built, why timing and mechanical force are part of the code, and why a dish of stem cells is only a window onto that process.
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