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2:51:17ENOumuamua Wasn't Supposed to Exist. Avi Loeb Wants a Photograph Next Time.Invitado: Avi Loeb · Presenta: Lex FridmanHarvard astrophysicist Avi Loeb tells Lex Fridman why the first interstellar visitor looks more like a lightsail than a rock — and why that question is still treated as unscientific.
2:17:42ENThe building block of life is a bead on a string, not the whole proteinInvitado: Dmitry Korkin · Presenta: Lex FridmanDmitry Korkin tells Lex Fridman why protein domains, a triangular spike, and a conservative viral shell matter more than the AlphaFold headline, and why a Nobel laureate once answered a midnight forum post.
1:37:46ENAll-In Debates Trump’s Platform Bans and Online Free ExpressionPresenta: Jason Calacanis, Chamath Palihapitiya, David Sacks, David FriedbergDays after the January 6 attack, the hosts disagree about platform power, public safety and how political opponents can reconcile.
1:16:12ENDan Gable Won the Olympics 57–0. He Still Talks About the Match He LostInvitado: Dan Gable · Presenta: Lex FridmanThe Iowa wrestling legend on Russian technique, American toughness, the murder of his sister, and why he took the word choice out of his life.
1:28:46ENThe Speech Company That Gets Paid to Label Its Own Training DataInvitado: Dan Kokotov · Presenta: Lex FridmanRev VP of engineering Dan Kokotov tells Lex Fridman why a $1.25-a-minute human transcript, a 14% machine word-error rate, and a two-sided freelancer market are the same flywheel.
3:08:23ENTake One Red Pill, Not the Whole BottleInvitado: Michael Malice · Presenta: Lex FridmanMichael Malice talks with Lex Fridman about humor as a filter, the White Pill, anarchism, and how to want happiness without swallowing cynicism.
3:01:27ENA Belief Does Not Have to Be True to Remake the WorldInvitado: Diana Walsh Pasulka · Presenta: Lex FridmanReligious-studies scholar Diana Walsh Pasulka tells Lex Fridman how Catholic limbo, Nietzsche, Silicon Valley “downloads,” and a desert monolith all describe the same machinery of belief and technology.
2:02:45ENSteal the Code: You Get Zero Points for Making the Algorithm RunPresenta: Lex FridmanCharles Isbell and Michael Littman tell Lex Fridman why machine learning is not just statistics, why struggle has to stay hopeful, and what a $6,600 online master's actually sells.
2:23:10ENBuilding a Driver, Not a Copilot: Waymo CTO Dmitri Dolgov on Fully Driverless CarsInvitado: Dmitri Dolgov · Presenta: Lex FridmanFrom a 3 a.m. parking-lot planner at Stanford to a public robotaxi in Phoenix, Dolgov tells Lex Fridman why driver assist and a real driver are different products.
2:18:26ENThe Dollar Paper Strip That Could Have Turned Covid's CurveInvitado: Michael Mina · Presenta: Lex FridmanHarvard immunologist Michael Mina tells Lex Fridman why twice-weekly antigen tests could have reversed the pandemic—and why regulation, not manufacturing, blocked them.
3:39:01ENMatthew Johnson on loosening the priors that run a human lifeInvitado: Matthew Johnson · Presenta: Lex FridmanThe Johns Hopkins psychiatrist walks Lex Fridman through receptors, addiction, DMT entities, a 15-person smoking trial, and why psychedelics have taught us almost nothing about the hard problem of consciousness.
2:01:07ENMichael Littman isn’t waiting for a runaway god. He’s watching us.Invitado: Michael Littman · Presenta: Lex FridmanThe Brown reinforcement-learning researcher tells Lex Fridman why accidental superintelligence feels like a 747 assembling itself — and why social media, rote language, and theory of mind worry him more.
2:59:53ENFor Every Triumph, Many Souls Must Be TrampledInvitado: John Clarke · Presenta: Lex FridmanJohn Clarke, Lex Fridman's jiu-jitsu coach, on why most people who train are not martial artists, and what excellence actually costs.
2:14:55ENHis Wife Calls Him the RadioInvitado: Manolis Kellis · Presenta: Lex FridmanMIT computational biologist Manolis Kellis spends the first forty minutes of his fourth Lex Fridman conversation on the songs that formed him, then turns to 42, dinosaurs, and why hunting for meaning matters more than finding it.
1:44:47ENErik Brynjolfsson on the Exponential Mismatch Remaking Work and PoliticsInvitado: Erik Brynjolfsson · Presenta: Lex FridmanThe Stanford economist tells Lex Fridman why COVID, AI, and social networks all punish linear intuition — and why shared prosperity is the only way the pie-growing story holds.
2:20:31ENThe Most Romantic Gift Lisa Feldman Barrett Ever Got Was a Six-Way PlugInvitado: Lisa Feldman Barrett · Presenta: Lex FridmanOn her second Lex Fridman Podcast, the neuroscientist traces how she fell in love over a 1992 bulletin board, why brains evolved to hunt rather than to think, and how a body budget can change a mood.
2:35:30ENOn a Perfectly Flat Floor, Heights Still WorkInvitado: Andrew Huberman · Presenta: Lex FridmanStanford neuroscientist Andrew Huberman talks with Lex Fridman about fear circuits, matching inner arousal to outer demand, and why the first minutes after sleep should not belong to someone else's timeline.
2:53:14ENYaron Brook on Ayn Rand: Reason, Selfishness, and a Fading EnlightenmentInvitado: Yaron Brook · Presenta: Lex FridmanThe Ayn Rand Institute's chairman walks Lex Fridman through Objectivism, from metaphysics and egoism to capitalism, anarchism, and why so many people still roll their eyes at Rand.
2:40:00ENThe Light Never Broke the Speed Limit. Space Itself Stretched.Invitado: Alex Filippenko · Presenta: Lex FridmanBerkeley astrophysicist Alex Filippenko talks dark energy, exploding stars, aliens, and how a 13.7-billion-year-old universe can be 45.7 billion light-years across.
1:02:52ENInside Jane Street’s Software Engineering InternshipYaron Minsky, Jeanne Van Briesen, Matt Else, Grace Zhang · Jane StreetThree former interns describe the real projects, mentorship and decisions that shaped their transition to full-time engineering.
3:26:04ENIf Hitler Thought He Was Helping Germany, Was Alexander Worse?Invitado: Dan Carlin · Presenta: Lex FridmanHardcore History host Dan Carlin talks with Lex Fridman about motives, force, strongmen, and why he would rather throw six weeks of tape away than ship something mediocre.
2:28:11ENPeople Are Easy to Predict — and They Hate Being Told SoInvitado: Charles Isbell · Presenta: Lex FridmanGeorgia Tech dean Charles Isbell talks with Lex Fridman about interactive AI, computing as a mindset, and race in America.
2:56:49ENEric Weinstein: Genius Is Sitting in the Wrong ChairInvitado: Eric Weinstein · Presenta: Lex FridmanOn his third Lex Fridman podcast, the mathematician moves from Eddie Van Halen and Leonard Cohen to Jeffrey Epstein, the Nobel committee, and why he paused The Portal.
2:39:45ENThe obesity gene was never the obesity geneInvitado: Manolis Kellis · Presenta: Lex FridmanManolis Kellis tells Lex Fridman how one nucleotide a million bases from FTO rewrote obesity biology, and why human genetics is now driving the study of disease.
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