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1:20:09ENStack Overflow Was Never Designed for BeginnersInvitado: Jeff Atwood · Presenta: Lex FridmanOn Stack Overflow’s tenth birthday, Jeff Atwood talks with Lex Fridman about puzzles, leadership, Discourse, and why a software team’s health is how fast it can change one word.
1:26:44ENHe raised Python like a child, then set it freeInvitado: Guido van Rossum · Presenta: Lex FridmanIn a 2018 conversation with Lex Fridman, Guido van Rossum traces Python from electronics kits and Conway's Game of Life to the Thursday morning he resigned as benevolent dictator for life.
1:14:23ENCristina Rosu: Building Dynamic OCaml Web Apps with Incr_domCristina Rosu · Jane StreetA practical introduction to the Elm architecture, virtual DOM and incremental computation, followed by a live counter-app demonstration.
1:00:51ENInflict Pain, But Do It With a Smile: Julia Schottenstein on dbt's Rise and the Art of Getting AcquiredInvitado: Julia Schottenstein · Presenta: Lenny RachitskyA former NEA investor turned dbt Cloud product leader explains why dbt won, how to approach M&A and pricing, and how venture habits make her a better PM.
56:20ENBiohub's Bet: Building Open AI World Models of Biology From Proteins Up to CellsPresenta: Sarah Guo, Elad GilMark Zuckerberg, Priscilla Chan and Alex Rives explain why Biohub pairs a frontier AI lab with frontier wet-lab biology, and why it releases tools like ESMFold2 as open source.
23:54ENBeyond GPT-7: The Customization Toolkit, Meta's Open Source Bet and the Return of Consumer AIPresenta: Sarah Guo, Elad GilIn a host-only episode, the No Priors hosts map the six levers for 10x to 100x better AI, explain fine-tuning, RAG and AI feedback, and ask why consumer social is suddenly interesting again.
1:34:27ENMatt Mullenweg on Open Source Ideals, the WP Engine Fight and Why Llama Isn't Really OpenInvitado: Matt Mullenweg · Presenta: Lenny RachitskyThe WordPress co-creator and Automattic CEO gives his side of the WP Engine dispute, explains his open source philosophy, and talks AI, community building and acquisitions with Lenny Rachitsky.
33:31ENOpen Source Catches Up, Regulation Can Wait: Sarah Guo and Elad Gil Answer Listener QuestionsPresenta: Sarah Guo, Elad GilTwo AI investors cover open-source models, autonomous agents, whether to regulate AI, where startups can win, and why healthcare innovation is so hard.
11:59ENFrom a Side Project to TensorFlow's Core: François Chollet on How Keras Came to BeInvitado: François Chollet · Presenta: Lex FridmanThe creator of Keras recalls why he built it in 2015 around recurrent networks, how it moved onto TensorFlow, and what TensorFlow 2.0 means for its design.









