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45:10EN
No Priors: AI, Machine Learning, Tech, & Startups· 10 sept 2026Pódcast · 2 voces76% of Agentic Commerce Is Under 30 Cents — So Coinbase Is Banking the AIsPresenta: Sarah Guo, Elad GilBrian Armstrong tells Elad Gil how Coinbase became an everything exchange, why card networks cannot price agent-to-agent payments, and what his longevity company is taking into the clinic.
44:01ENNo Priors: AI, Machine Learning, Tech, & Startups· 9 abr 2026Pódcast · 2 vocesA millionth of a penny: Jeremy Allaire on the payment rails of the agentic economyPresenta: Sarah Guo, Elad GilCircle's CEO tells No Priors why stablecoins and a purpose-built chain, not the legacy banking stack, are the money layer for software that buys and sells on its own.
48:14ENNo Priors: AI, Machine Learning, Tech, & Startups· 13 nov 2025Pódcast · 2 vocesA New Drug Burns $2 Billion and 10 Years. Benchling's CEO Wants AI to Cut That to ThreePresenta: Sarah Guo, Elad GilMost medicines fail in years seven to ten, after hundreds of millions have already gone into the clinic—and Sajith Wickramasekara thinks sending things to space may already be easier.
31:22ENNo Priors: AI, Machine Learning, Tech, & Startups· 18 sept 2025Pódcast · 2 vocesDecagon Prices AI Support by the Conversation. The Market Is Wages.Presenta: Sarah Guo, Elad GilJesse Zhang on six-figure contracts at zero ARR, 60–70% contact-center cuts, and a world where your agent calls the airline’s agent.
42:12ENNo Priors: AI, Machine Learning, Tech, & Startups· 21 ago 2025Pódcast · 2 vocesHire the AI First: Andrew Ng on Agentic Workflows and the Scarcity of JudgmentPresenta: Sarah Guo, Elad GilOn No Priors, Andrew Ng argues that agentic AI has made software cheap and fast, which moves the bottleneck to product judgment, error analysis, and the instinct to try an AI before adding headcount.
41:25ENNo Priors: AI, Machine Learning, Tech, & Startups· 12 jun 2025Pódcast · 2 vocesBen Mann thinks superintelligence by 2028 is quite possiblePresenta: Sarah Guo, Elad GilAnthropic's co-founder tells No Priors how Claude 4 unlocked hours of unattended agent work, why the lab built Claude Code, and what an economic Turing test would actually measure.
30:46ENNo Priors: AI, Machine Learning, Tech, & Startups· 24 abr 2025Pódcast · 2 vocesDeep Research Turned Web Browsing into a Trainable ProblemPresenta: Sarah Guo, Elad GilOpenAI researcher Isa Fulford explains why a side project on read-only synthesis became an agent, when reinforcement fine-tuning is worth it, and why models will hack the search engine you gave them.
30:09ENNo Priors: AI, Machine Learning, Tech, & Startups· 16 ene 2025Pódcast · 2 vocesBilt Saved 65 Support Seats. Decagon's Founder Says Most Agent Ideas Still Won't SellPresenta: Sarah Guo, Elad GilJesse Zhang on why customer support is the golden agent use case, why instruction following beats o1-style reasoning, and the two filters that kill most agent startups.
39:22ENNo Priors: AI, Machine Learning, Tech, & Startups· 14 nov 2024Pódcast · 2 vocesA Fields Medalist Stuck for Two Hours. AlphaProof Climbed for Three Days.Presenta: Sarah Guo, Elad GilThe DeepMind team behind AlphaProof tells Sarah Guo and Elad Gil how an AlphaZero-style agent, a Lean verifier, and test-time reinforcement learning reached IMO silver — and why the missing skill is still theory building.
48:31ENNo Priors: AI, Machine Learning, Tech, & Startups· 19 sept 2024Pódcast · 2 vocesA Call Center Contact Costs $13. A Company Agent Can Do It for Under a DollarPresenta: Sarah Guo, Elad GilSierra cofounder and OpenAI chairman Bret Taylor tells No Priors why branded customer agents are shovel-ready, why RAG demos are not products, and how AI software should charge for the job done.
27:32ENNo Priors: AI, Machine Learning, Tech, & Startups· 28 mar 2024Pódcast · 2 vocesFrom a side project to 700 integrations: Harrison Chase on what still blocks agentsPresenta: Sarah Guo, Elad GilThe LangChain CEO walks through a two-year churn of patterns, and why memory, planning, and few-shot data still matter more than swapping models.
32:48ENNo Priors: AI, Machine Learning, Tech, & Startups· 16 nov 2023Pódcast · 2 vocesFourteen People, $200 Million of Compute, and the Reliability Bottleneck for AgentsPresenta: Sarah Guo, Elad GilImbue co-founders Kanjun Qiu and Josh Albrecht on why agents fail, why language models cannot learn general algorithms, and why they are spending a giant round on GPUs rather than headcount.
42:25ENNo Priors: AI, Machine Learning, Tech, & Startups· 15 sept 2023Pódcast · 2 vocesThe Transformer Co-Author Who Wants to Give AI a WalletPresenta: Sarah Guo, Elad GilIllia Polosukhin, co-author of Attention Is All You Need and co-founder of NEAR, argues that a blockchain account turns a language-model agent into an economic actor that can hire people and other AIs.
51:55ENNo Priors: AI, Machine Learning, Tech, & Startups· 11 may 2023Pódcast · 2 vocesNine orders of magnitude later, he shipped a companion, not an oraclePresenta: Sarah Guo, Elad GilDeepMind co-founder Mustafa Suleyman tells No Priors why Inflection’s first product is a personal AI that sits in your corner, and why the missing piece is a router, not a bigger model.
1:00:36ENNo Priors: AI, Machine Learning, Tech, & Startups· 2 feb 2023Pódcast · 2 vocesForty games of Diplomacy, and nobody spotted the bot: Noam Brown’s 100,000x lessonPresenta: Sarah Guo, Elad GilMeta’s Noam Brown tells Sarah Guo and Elad Gil how Cicero negotiated in English for 40 games on a tiny web community — and why thinking at decision time beat three years of scaling.
29:03ENNo Priors: AI, Machine Learning, Tech, & StartupsPódcast · 2 vocesNotion's Simon Last on Rewriting the AI Harness Every Six Months and Managing a Swarm of AgentsPresenta: Sarah Guo, Elad GilThe Notion co-founder traces the product's path from a writing assistant to custom background agents, and describes how coding agents changed the way he builds.