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45:17EN
No Priors: AI, Machine Learning, Tech, & Startups· 7 ago 2025Pódcast · 2 vocesA Click From OpenAI Is 750 Times Harder Than From Google a Decade AgoPresenta: Sarah Guo, Elad GilCloudflare CEO Matthew Prince on Content Independence Day, why traffic is a broken proxy for value, and how to price the holes in the models.Empresa y estrategiaAI StrategyPricing Strategy+3
36:48EN
No Priors: AI, Machine Learning, Tech, & Startups· 31 jul 2025Pódcast · 2 vocesThe Weekend DeepSeek Dropped, the White House CalledPresenta: Sarah Guo, Elad GilSriram Krishnan walks No Priors through America’s 28-page AI Action Plan, a token-share definition of winning, and why the lead over China is too small to take for granted.Empresa y estrategiaAI StrategyInfraestructura y despliegue+3
32:59EN
No Priors: AI, Machine Learning, Tech, & Startups· 24 jul 2025Pódcast · 2 vocesA Hundred People, a Billion in Revenue, and Zero Venture MoneyPresenta: Sarah Guo, Elad GilSurge AI founder Edwin Chen on why quality human data is a poetry problem, not a bounding-box problem, and why leaderboards keep training models to write clickbait.Evaluaciones y observabilidadData quality & curationValidación con humanos en el bucle+3
1:02:54EN
No Priors: AI, Machine Learning, Tech, & Startups· 17 jul 2025Pódcast · 2 vocesEnterprise Coding Tools Flipped the 80/20. Reflection AI Built the Other HalfPresenta: Sarah Guo, Elad GilFormer Gemini reward-model lead Misha Laskin on Asimov, why comprehension beats generation, and why there is no such thing as generalization—only pulling the test distribution into train.Agentes de programaciónIngeniería de agentesEvaluaciones+3
44:44EN
No Priors: AI, Machine Learning, Tech, & Startups· 10 jul 2025Pódcast · 2 voces$1 of R&D, 35x the return: why Parker Conrad says platforms beat point solutionsPresenta: Sarah Guo, Elad GilThe Rippling CEO on Zenefits, founder psychology, and why shared underlying capabilities—not narrow focus—win in enterprise software.Empresa y estrategiaCompany BuildingProduct Strategy+3
49:27EN
No Priors: AI, Machine Learning, Tech, & Startups· 3 jul 2025Pódcast · 2 vocesFrom 0.1% to 20%: Chai-2 Turns Antibody Design Into Prompt EngineeringPresenta: Sarah Guo, Elad GilChai Discovery co-founders Joshua Meier and Jack Dent tell Sarah Guo how a generative model now designs antibodies that bind on the first 24-well plate.AI for scienceDrug DiscoveryAI startups & small teams+3
42:09EN
No Priors: AI, Machine Learning, Tech, & Startups· 26 jun 2025Pódcast · 2 vocesAlphaEvolve found algorithms humans missed for 50 years — then sped up Gemini 23%Presenta: Sarah Guo, Elad GilGoogle DeepMind’s Pushmeet Kohli and Matej Balog tell No Priors how an evolutionary coding agent searches algorithm space the way AlphaGo searched Go.Agentes de programaciónIngeniería de agentesEvaluaciones+3
45:21EN
No Priors: AI, Machine Learning, Tech, & Startups· 17 jun 2025Pódcast · 2 vocesApplied Intuition Is Worth $15 Billion, Hasn't Spent Its Capital, and Wants to Be the OS for Cars and TanksPresenta: Sarah Guo, Elad GilOn No Priors, Qasar Younis and Peter Ludwig explain the Microsoft playbook for vehicles, why they waited for autonomy techniques to converge, and why Waymo's business model is the question that follows the demo.Empresa y estrategiaAutonomous DrivingCompany Building+3
41:25EN
No Priors: AI, Machine Learning, Tech, & Startups· 12 jun 2025Pódcast · 2 vocesBen Mann thinks superintelligence by 2028 is quite possiblePresenta: Sarah Guo, Elad GilAnthropic's co-founder tells No Priors how Claude 4 unlocked hours of unattended agent work, why the lab built Claude Code, and what an economic Turing test would actually measure.AgentesAgentes de programaciónIngeniería de agentes+3
35:47EN
No Priors: AI, Machine Learning, Tech, & Startups· 5 jun 2025Pódcast · 2 vocesFei-Fei Li’s new bet: AI is incomplete without spatial intelligencePresenta: Sarah Guo, Elad GilThe ImageNet pioneer tells Sarah Guo and Elad Gil why World Labs is building 3D generative foundation models, and why language was only one piece of the puzzle.Multimodal y mediosMultimodal AIVisión y vídeo+3
25:13EN
No Priors: AI, Machine Learning, Tech, & Startups· 29 may 2025Pódcast · 2 vocesThe AI Table Is Being Cleared: Two or Three Coding Winners, and Forty Years Without a Biotech GiantPresenta: Sarah Guo, Elad GilSarah Guo and Elad Gil walk through which AI markets have already consolidated, why rival startups still refuse to merge, and the biotech science sitting unused.Empresa y estrategiaAI StrategyCompany Building+3
31:34EN
No Priors: AI, Machine Learning, Tech, & Startups· 15 may 2025Pódcast · 2 vocesOne Company Now Holds as Many Documents as the Entire Early WebPresenta: Sarah Guo, Elad GilGlean CEO Arvind Jain tells No Priors why enterprise search was a graveyard, how transformers finally made it work, and why a product that searches too well can be too dangerous to sell.RAG y conocimientoIA empresarialSearch & retrieval+3
32:15EN
No Priors: AI, Machine Learning, Tech, & Startups· 8 may 2025Pódcast · 2 vocesThe Hardest Part of Learning Is Getting Yourself to StartPresenta: Sarah Guo, Elad GilDuolingo CEO Luis von Ahn tells Sarah Guo how two-minute lessons, streaks, an 83 percent accuracy target, and large language models turned language study into a consumer product.Producto y UXProduct StrategyAI in Education+3
38:10EN
No Priors: AI, Machine Learning, Tech, & Startups· 1 may 2025Pódcast · 2 voceso3 should wait exactly as long as the answer takesPresenta: Sarah Guo, Elad GilOpenAI researchers Eric Mitchell and Brandon McKinzie tell No Priors why o3's leap is a chain of tools during reasoning — and why you should send the same prompt a hundred times.Modelos y entrenamientoReasoning & test-time computeReinforcement Learning+3
30:46EN
No Priors: AI, Machine Learning, Tech, & Startups· 24 abr 2025Pódcast · 2 vocesDeep Research Turned Web Browsing into a Trainable ProblemPresenta: Sarah Guo, Elad GilOpenAI researcher Isa Fulford explains why a side project on read-only synthesis became an agent, when reinforcement fine-tuning is worth it, and why models will hack the search engine you gave them.AgentesIngeniería de agentesReinforcement Learning+3
40:54EN
No Priors: AI, Machine Learning, Tech, & Startups· 17 abr 2025Pódcast · 2 vocesDiscovery rates collapsed tenfold. KoBold still found a 5% copper depositPresenta: Sarah Guo, Elad GilJosh Goldman explains why KoBold Metals treats mineral exploration as an information problem, pairing AI with century-old maps to hunt lithium and copper.Empresa y estrategiaAI for scienceData quality & curation+3
41:52EN
No Priors: AI, Machine Learning, Tech, & Startups· 10 abr 2025Pódcast · 2 vocesMercor Hit $100 Million ARR Teaching Models to Hire. Humans Now Write the Exams.Presenta: Sarah Guo, Elad GilBrendan Foody tells Sarah Guo and Elad Gil how Mercor automated recruiting for frontier labs — and why building evals may become the world's most common knowledge job.Empresa y estrategiaEvaluacionesIngeniería de agentes+3
27:45EN
No Priors: AI, Machine Learning, Tech, & Startups· 3 abr 2025Pódcast · 2 vocesNasdaq Down 8% and Ghibli Everywhere: AI Is Already in Inning ThreePresenta: Sarah Guo, Elad GilSarah Guo and Elad Gil on the latest image-gen wow cycle, why public-market panic is mostly noise for software startups, and where specialized models still have room.Empresa y estrategiaAI StrategyGenerative media+3
38:43EN
No Priors: AI, Machine Learning, Tech, & Startups· 27 mar 2025Pódcast · 2 vocesTwo in Five Doctors Want Out. An On-Call Cardiologist Built the Note That Lets Them StayPresenta: Sarah Guo, Elad GilAbridge CEO Shiv Rao on treating the doctor-patient conversation as healthcare's source of truth, and why the company ran straight at the hardest health systems.Empresa y estrategiaAI in healthcareIA de voz+3
35:14EN
No Priors: AI, Machine Learning, Tech, & Startups· 20 mar 2025Pódcast · 2 vocesRobots Have No Wikipedia. Chelsea Finn Is Starting With Three Buildings.Presenta: Sarah Guo, Elad GilPhysical Intelligence’s cofounder tells No Priors why a generalist robot model has to be trained across embodiments, why open-sourcing hardware is a bet against the problem going unsolved, and why humanoids are a little overrated.Modelos y entrenamientoRoboticsData quality & curation+3
50:35EN
No Priors: AI, Machine Learning, Tech, & Startups· 13 mar 2025Pódcast · 2 vocesCopilot Already Writes Half the Code. GitHub's CEO Says Agents Still Have Four Gates to ClearPresenta: Sarah Guo, Elad GilThomas Dohmke on agent mode, why median developers are not going anywhere, and how AI is repricing the tools that write software.Agentes de programaciónFlujos de desarrollo y pruebasIngeniería de agentes+3
36:24EN
No Priors: AI, Machine Learning, Tech, & Startups· 5 mar 2025Pódcast · 2 vocesThe Man Behind Humanity's Last Exam Says Superintelligence Strategy Should Copy NukesPresenta: Sarah Guo, Elad GilDan Hendrycks tells No Priors that labs can only do basic anti-terror refusals, while the real risk-management problem is a geopolitical deterrent he calls mutually assured AI malfunction.SeguridadSeguridad y gobernanzaAI security+3
40:33EN
No Priors: AI, Machine Learning, Tech, & Startups· 27 feb 2025Pódcast · 2 vocesModerna was only company 18. The real product is the company factoryPresenta: Sarah Guo, Elad GilNoubar Afeyan tells No Priors how Flagship Pioneering turned starting companies into a profession, underwrites scientific uncertainty, and wants AI to run discovery the way Waymo drives.Empresa y estrategiaCompany BuildingAI for science+3
57:41EN
No Priors: AI, Machine Learning, Tech, & Startups· 25 feb 2025Pódcast · 2 vocesA Hundred Million Cells, Four People, Three Days: Biology's ImageNet MomentPresenta: Sarah Guo, Elad GilVevo Therapeutics and the Arc Institute open-sourced Tahoe-100M and a 230-million-cell atlas in the same week — and argued that virtual cells, not just protein folders, are the next language model of biology.Modelos y entrenamientoAI for scienceData quality & curation+3
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