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38:14ENDiffusion Will Win Inference: Stefano Ermon Bets Parallel Tokens Beat Custom SiliconHost Sarah Guo, Elad GilThe Stanford diffusion pioneer tells No Priors why a 50-person lab is training language models that generate many tokens at once — and why that maps to GPUs the way transformers once mapped to training.
3:36:13ENNVIDIA’s Ming-Yu Liu on Cosmos, Physical AI, and Creating New MarketsGuest Ming-Yu Liu · Host 张小珺NVIDIA research VP Ming-Yu Liu explains how a decade of generative-model research led to Cosmos 3, a world foundation model for Physical AI. He also shares what he learned from Jensen Huang about long-term bets, teamwork, and building markets instead of fighting over existing ones.
2:59:03ENYou Kaichao on How vLLM Grew from Open-Source Project to AI Infrastructure CompanyGuest You Kaichao · Host 张小珺Inferact co-founder You Kaichao traces vLLM’s path from Berkeley research to a company, then explains why model, inference, hardware and agent design increasingly have to move together.
3:46:12ENKay Ke on Physical Intelligence, Robot Learning, and the Future of RoboticsGuest Kay Ke · Host 张小珺Physical Intelligence researcher Kay Ke traces the field's research lineages and explains Pi's progression from π₀ to π*₀.₆. She also reflects on education, fiction, ambition, and what it means to build robots that work beyond a demo.
36:19ENThe Benchmark Grid Is Broken: Why Test-Time Compute Has Outrun How We Score ModelsHost Sarah Guo, Elad GilOpenAI researcher Noam Brown argues that static leaderboards hide how long a model is allowed to think — and that safety evals, research taste, and the release cycle have not caught up.
32:22ENDemis Hassabis on AGI, Scientific Discovery and the Challenges AheadGuest Demis Hassabis · Host Harry StebbingsThe Google DeepMind CEO discusses compute, continual learning, safety standards and his hopes for AI in science, medicine and energy.
13:30ENHow AlphaGeometry Combines Logical Proof with Creative ConstructionAleph0Aleph0 explains how a symbolic geometry solver gets surprisingly far without AI, and how a language model supplies the auxiliary constructions that take it to Olympiad level.
42:09ENAlphaEvolve found algorithms humans missed for 50 years — then sped up Gemini 23%Host Sarah Guo, Elad GilGoogle DeepMind’s Pushmeet Kohli and Matej Balog tell No Priors how an evolutionary coding agent searches algorithm space the way AlphaGo searched Go.
3:14:34ENIf ten things make a problem hard, Terence Tao turns nine of them offGuest Terence Tao · Host Lex FridmanThe Fields Medalist walks Lex Fridman from the Kakeya needle and Navier-Stokes through Lean, Perelman, and why today's AI still cannot smell a dead-end proof.
38:10ENo3 should wait exactly as long as the answer takesHost Sarah Guo, Elad GilOpenAI researchers Eric Mitchell and Brandon McKinzie tell No Priors why o3's leap is a chain of tools during reasoning — and why you should send the same prompt a hundred times.
2:36:13ZH → EnglishSonglin Yang on New Attention Papers from DeepSeek, Kimi, and MiniMaxGuest Songlin Yang(松琳) · Host 张小珺From dynamic sparse attention to hybrid linear-attention architectures: how three approaches to long context balance training, inference, and hardware efficiency.
53:07ZH → EnglishZhang Yaqin on the AGI Roadmap: Information, Physical, and Biological IntelligenceGuest 张亚勤 · Host 张小珺Zhang Yaqin divides AGI’s development into information, physical, and biological intelligence. Information intelligence may approach human levels within five years, general-purpose robots may take about ten, and biological intelligence could expand human memory and health in twenty. He also discusses how large models can give autonomous vehicles and robots more data, common sense, and ability to act.
45:31ENJerry Chow on Quantum Computing, Encryption, AI and Error CorrectionMatthew Berman, Jerry Chow · Forward FutureIBM’s quantum systems director explains qubits, cryogenic hardware, software and the work needed to make quantum computers useful.
2:49:35ZH → EnglishPan Jiayi on R1, o1, and Kimi K1.5: How Reinforcement Learning Teaches Models to ReasonGuest 潘嘉怡 · Host 张小珺Pan Jiayi, a Berkeley PhD student, walks through reasoning-model reports from DeepSeek, OpenAI, and Kimi, unpacking long chains of thought, GRPO, reward design, and distillation. R1-Zero’s “aha moment” shows how reasoning strategies can emerge through reinforcement learning.
1:33:07ZH → EnglishLi Guangmi on a Year in Global LLMs: Scaling Law, the AGI Bet, and the US–China LandscapeGuest 李广密 · Host 张小珺Drawing on his front-row view from Silicon Valley, Shixiang Capital founder Li Guangmi looks back at the competition among OpenAI, Anthropic, Google, and Chinese model companies. He argues that model capability and cost together will shape the next wave of applications, while today’s enormous investments are bets on whether intelligence can keep scaling and how AI will reshape the economy and industry over the long term.
34:09ENFive Independent Teams Found the Same 10-to-1 Mix That Beats TransformersHost Sarah Guo, Elad GilThe authors of S4 and Mamba argue that mostly state-space layers plus a dash of attention is the architecture that actually works—and they are shipping it first as real-time speech.
26:00ENWhy a Zapier founder thinks AGI research has been stalled for four yearsHost Sarah Guo, Elad GilMike Knoop and François Chollet put more than a million dollars on beating ARC-AGI, the eval they say actually measures general intelligence.
2:15:39ENRoman Yampolskiy Puts Superintelligent Ruin at 99.99 PercentGuest Roman Yampolskiy · Host Lex FridmanThe AI safety researcher tells Lex Fridman that controlling AGI is as impossible as a perpetual motion machine, and that tests, open source, and regulation cannot close the gap.
2:50:44ENThe Pirahã Have No Word for OneGuest Edward Gibson · Host Lex FridmanMIT psycholinguist Ted Gibson tells Lex Fridman why related words sit together, why language is not thought, and why large language models ace form while missing meaning.
2:47:17ENIf You Want Human-Level AI, Abandon Generative ModelsGuest Yann Lecun · Host Lex FridmanYann LeCun tells Lex Fridman why autoregressive LLMs cannot plan, remember, or understand the physical world — and why open source is the only democratic answer.
41:58ENReliability is the bottleneck. Autonomy is what would make AI feel alive.Host Sarah Guo, Elad GilIlya Sutskever talks with Sarah Guo and Elad Gil about AlexNet, OpenAI’s capped-profit bet, why smaller models mainly lose reliability, and the line he draws for digital life.
39:50ENWhy AI Video Is Still a Four-Second CorgiHost Sarah Guo, Elad GilMeta research director Devi Parikh explains why text-to-video has stalled on short animated images, and what it will take to get past that plateau.
3:11:35ENSearch was always a hack: Marc Andreessen on AI, truth, and the next internetGuest Marc Andreessen · Host Lex FridmanLex Fridman sits down with the Mosaic co-creator and Andreessen Horowitz founder to ask whether Google Search, the browser, and open-source AI survive the decade.
2:07:04ENThe Ribosome Already Solved Digital ManufacturingGuest Neil Gershenfeld · Host Lex FridmanNeil Gershenfeld tells Lex Fridman why Turing separated the head from the tape, how fab labs are the personal-computer moment for making things, and what it would take to grow a civilization from about twenty parts.
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