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1:04:51EN
Cognitive Revolution "How AI Changes Everything"· Feb 1, 2026Podcast125 million cells took a decade. The next billion takes monthsHost Nathan LabenzMark Zuckerberg and Priscilla Chan on pairing a frontier biology lab with a frontier AI lab so models train on data that was designed for them.
1:18:05EN
Unsupervised Learning: With Jacob Effron· Dec 18, 2025PodcastThe Real Bottleneck in AI Research Is Compute, Not IdeasHost Jacob EffronAfter NeurIPS, Ari Morcos and Rob Toews sit down with Jacob Effron to argue about plateauing models, SSI’s secrecy, OpenAI’s cash burn, and a set of spicy 2026 bets.
48:00ENUnsupervised Learning: With Jacob Effron· Dec 15, 2025PodcastA Two-Second Vote Is Training Models to Be ClickbaitHost Jacob EffronSurge AI CEO Edwin Chen tells Redpoint why LMArena rewards length and emojis, how one lab's models got worse for a year, and why frontier labs are no longer on the same path.
1:32:38ENCognitive Revolution "How AI Changes Everything"· Dec 6, 2025PodcastPolish Is 1% of Frontier Training Data, So Poland Built Its Own ModelHost Nathan LabenzMarek Kozlowski of Poland's National Information Processing Institute explains how PLLuM uses language adaptation, organic instructions, and on-prem small models to keep a mid-size country in control of its AI.
1:16:53ENUnsupervised Learning: With Jacob Effron· Oct 24, 2025PodcastKarpathy Called Today's Models Slop. His Decade Timeline Still Sounds BullishHost Jacob EffronDatology AI's Ari Morcos and Radical Ventures' Rob Toews walk through Karpathy's cold water, OpenAI's dealmaking, and who actually pays for the data-center boom.
1:01:49ENCognitive Revolution "How AI Changes Everything"· Oct 2, 2025PodcastChatGPT's Co-Creator Left to Put Nature in the Reward LoopHost Nathan LabenzLiam Fedus and Ekin Dogus Cubuk on why language models still fail at physics, why literature data is too noisy to train on, and why Periodic Labs is aiming at a 200K superconductor.
1:22:07ENCognitive Revolution "How AI Changes Everything"· Sep 25, 2025PodcastEvery payment is a frame in a movie. Stripe’s foundation model took card-testing detection from 59% to 97%Host Nathan LabenzEmily Sands, Stripe’s head of data and AI, explains how a domain-specific payments model, shared embeddings, and mixed rules turn a $1.4 trillion network into compounding advantage.
1:55:02ENCognitive Revolution "How AI Changes Everything"· Aug 30, 2025PodcastA hundred experiments a day, and the valley of death in materialsHost Nathan LabenzRadical AI’s co-founders tell Nathan Labenz how a closed loop of frontier models and a self-driving lab is meant to collapse a forty-year materials cycle into less than a decade.
57:52ENUnsupervised Learning: With Jacob Effron· Aug 13, 2025PodcastThey Aimed for 1%. The Lab Hit 20%. Chai Discovery Moved Antibody Design Onto the Computer.Host Jacob EffronJoshua Meier on three waves of AI drug discovery, why Chai-2 behaves like Photoshop for molecules, and why a 1% hit rate was supposed to be enough to change the industry.
23:39ZH → English
跟李沐学AI· Jul 23, 2025Li Mu: Adding Ten Million Hours of Speech to a Text LLM, Open-Sourcing Higgs Audio李沐 · Boson AILi Mu explains how the team added a huge amount of speech data to text LLM training, built an AudioLLM that can listen and speak, and open-sourced Higgs Audio. He covers architecture trade-offs, token compression, where the data came from, and how to run it on a 3090.
1:42:06ENCognitive Revolution "How AI Changes Everything"· Jul 8, 2025PodcastEvery Frontier Lab Is Spending a Billion a Year on Data. Here Is Where It GoesHost Nathan LabenzLabelbox CEO Manu Sharma on the $15 billion Scale deal, RL “gyms,” $250,000 trainers, and why post-training now eats the budget that used to belong to pre-training.
44:21ENUnsupervised Learning: With Jacob Effron· Jun 4, 2025PodcastMercor's CEO: Knowledge Work's Next Job Is Writing EvalsHost Jacob EffronBrendan Foody tells Redpoint how Mercor turned AI hiring and expert data into a $100 million round — and why he thinks a huge slice of white-collar work will become creating tests for models.
1:43:54ENCognitive Revolution "How AI Changes Everything"· Mar 23, 2025PodcastA Year to Grow a Brain Organoid, an Hour to Simulate ItHost Nathan LabenzStanford postdoc Siyu He tells Nathan Labenz how Squidiff and CORAL move single-cell and spatial experiments into the computer — and where the models still cannot go.
1:40:22ENCognitive Revolution "How AI Changes Everything"· Jan 22, 2025PodcastTwenty-atom crystals taught an AI the physics of a heartbeatHost Nathan LabenzOrbital Materials' Jonathan Godwin and Tim Duignan tell Nathan Labenz how a neural network trained on tiny crystals simulated a potassium ion channel on a single 2017 GPU.
1:27:33ENCognitive Revolution "How AI Changes Everything"· Dec 3, 2024PodcastA 70B Model Booked Dinner 20% of the Time. MultiOn Took It to 95% in a DayHost Nathan LabenzMultiOn CEO Div Garg returns to The Cognitive Revolution to recap 18 months of agent hype, the AgentQ stack, and why 2025 might still be the year of vertical agents.
1:49:41ENCognitive Revolution "How AI Changes Everything"· Nov 21, 2024PodcastA Team of Fifteen Matched Meta’s Post-Training on Meta’s Own BaseHost Nathan LabenzNathan Lambert walks through Tulu 3: the three-stage recipe, the 1 percent versus 14 percent lesson, and why open post-training now lives or dies on data and evals.
56:10ENUnsupervised Learning: With Jacob Effron· Oct 29, 2024PodcastDeepL Beat Google at Translation by Refusing to Be a General ModelHost Jacob EffronOnly 18 percent of the world speaks English—and a Cologne startup turned that fact into a $2 billion language-AI company.
1:13:23ENCognitive Revolution "How AI Changes Everything"· Oct 12, 2024PodcastAn AI Found a GABA-Cancer Link. The Next Step Is Talking to the Cells.Host Nathan LabenzMichael Levin and Leo Pio Lopez on a multilayer embedding that predicted melanoma, a cancer with no mutations, and why biology's real interface is cognitive.
1:16:11ENCognitive Revolution "How AI Changes Everything"· Jul 11, 2024PodcastScooping Food Into Boxes Is 70 Percent of Plant LaborHost Nathan LabenzChef Robotics CEO Rajat Bhageria on 20 million plated meals, a foundation model for food, and why the kitchen may leave the house.
1:01:39ENCognitive Revolution "How AI Changes Everything"· Apr 13, 2024PodcastGPT-5 Wants 100 Trillion Tokens. Does Earth Have Enough?Host Nathan LabenzTraining GPT-3 took about a trillion tokens; GPT-4 took about ten trillion. The next jump is a data question as much as a compute one.
1:21:50ENCognitive Revolution "How AI Changes Everything"· Nov 14, 2023PodcastA 16K Context Window Holds About 350 Rows. That's Why Tables Need an Agent.Host Nathan LabenzGretel AI founder Alex Watson tells Nathan Labenz why most company data is still a spreadsheet, why GPT-4 is the wrong tool for generating it, and how differential privacy lets a model learn a disease without learning a patient.
1:32:40ENCognitive Revolution "How AI Changes Everything"· Oct 31, 2023PodcastThe Historian Who Taught GPT-3.5 to Beat GPT-4Host Nathan LabenzMark Humphries on a kilometer of unread paper, fur-trade jargon that embeddings cannot see, and why cheap processing will force history to be rewritten.
2:15:11ENCognitive Revolution "How AI Changes Everything"· Sep 22, 2023PodcastTwenty Gibberish Tokens Jailbroke ChatGPT and BardHost Nathan LabenzCarnegie Mellon’s Zico Kolter, Andy Zou, and Asher Trockman walk through a universal jailbreak that transfers from open models to commercial APIs, and a training-free way to steal some of pretraining’s benefit.
59:28ENCognitive Revolution "How AI Changes Everything"· Jun 16, 2023PodcastFrom $500,000 to $50,000: MosaicML Made Training Your Own Model a Priced ProductHost Nathan LabenzJonathan Frankle and Abhi Venigalla explain who is training custom LLMs, why extraction beats chat, and how ALiBi stretches a 65k context window.Load moreShowing 24 of 32