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39:23EN
No Priors: AI, Machine Learning, Tech, & Startups· Oct 15, 2026Podcast · 2 speakersThe Defenders' Window: Greg Brockman on AI-Generated Knowledge, Drug Discovery, and the New Physics of CybersecurityHost Sarah Guo, Elad GilOpenAI's president explains why solving open math problems is a proof point for science, how proactive agents change product form, and why security spending must exceed software spending.Security & safetyAI securitySafety & governance+3
1:01:27EN
No Priors: AI, Machine Learning, Tech, & Startups· Jul 2, 2026Podcast · 2 speakersTwo Years and Four Months to a Live Reactor: Valar Atomics Wants Energy Ten Times CheaperHost Sarah Guo, Elad GilIsaiah Taylor walks Sarah Guo through Ward 250 in Utah and argues that nuclear is a hardware-iteration problem, not a paper-design one.Infrastructure & deploymentCompany BuildingSafety & governance+3
36:19EN
No Priors: AI, Machine Learning, Tech, & Startups· Jun 26, 2026Podcast · 2 speakersThe Benchmark Grid Is Broken: Why Test-Time Compute Has Outrun How We Score ModelsHost Sarah Guo, Elad GilOpenAI researcher Noam Brown argues that static leaderboards hide how long a model is allowed to think — and that safety evals, research taste, and the release cycle have not caught up.Evals & observabilityEvalsBenchmarks+3
41:09EN
No Priors: AI, Machine Learning, Tech, & Startups· May 28, 2026Podcast · 2 speakersAfter Agents Leak Tokens and Wipe Databases, Onyx Trains Small Models to Watch the Big OnesHost Sarah Guo, Elad GilTwo years ago enterprise security buyers told Maxim Bar Kogan he was too early. Now Fortune 10 companies are calling a sub-100-person Israeli startup because they cannot stop agent adoption — only reduce the chance the next action is illegitimate.Security & safetyAI securityAgent engineering+3
2:36:55EN
Lex Fridman· Nov 17, 2025Podcast · 2 speakersOne Second of Fuel: David Kirtley on Fusion Power by 2028Guest David Kirtley · Host Lex FridmanThe Helion Energy CEO walks Lex Fridman from 1958 theta pinches to a Microsoft contract that wants first electrons on the grid in 2028.Safety & governanceEnergyFirst Principles+2
18:59EN
No Priors: AI, Machine Learning, Tech, & Startups· Oct 31, 2025Podcast · 2 speakers86 Out of 100: The Clips No Priors Could Not Leave on the Cutting-Room FloorHost Sarah Guo, Elad GilSarah Guo and Elad Gil stitch nine 2025 conversations into one short tour of legal AI, spatial intelligence, jobs, deterrence, and a doctor who made it home for dinner.Enterprise & strategyAI StrategyCompany Building+3
58:21EN
No Priors: AI, Machine Learning, Tech, & Startups· Oct 4, 2025Podcast · 2 speakersAttacks Take 23 Minutes. Response Still Takes Days.Host Sarah Guo, Elad GilPalo Alto Networks CEO Nikesh Arora on how AI is remaking search, enterprise software, and the timeline of a cyberattack.Enterprise & strategyAI securityEnterprise AI+3
41:25EN
No Priors: AI, Machine Learning, Tech, & Startups· Jun 12, 2025Podcast · 2 speakersBen Mann thinks superintelligence by 2028 is quite possibleHost Sarah Guo, Elad GilAnthropic's co-founder tells No Priors how Claude 4 unlocked hours of unattended agent work, why the lab built Claude Code, and what an economic Turing test would actually measure.AgentsCoding agentsAgent engineering+3
30:46EN
No Priors: AI, Machine Learning, Tech, & Startups· Apr 24, 2025Podcast · 2 speakersDeep Research Turned Web Browsing into a Trainable ProblemHost Sarah Guo, Elad GilOpenAI researcher Isa Fulford explains why a side project on read-only synthesis became an agent, when reinforcement fine-tuning is worth it, and why models will hack the search engine you gave them.AgentsAgent engineeringReinforcement Learning+3
36:24EN
No Priors: AI, Machine Learning, Tech, & Startups· Mar 5, 2025Podcast · 2 speakersThe Man Behind Humanity's Last Exam Says Superintelligence Strategy Should Copy NukesHost Sarah Guo, Elad GilDan Hendrycks tells No Priors that labs can only do basic anti-terror refusals, while the real risk-management problem is a geopolitical deterrent he calls mutually assured AI malfunction.Security & safetySafety & governanceAI security+3
5:15:00EN
Lex Fridman· Nov 11, 2024Podcast · 2 speakersDario Amodei Has Seen This Scaling Movie Enough TimesGuest Dario Amodei · Host Lex FridmanAnthropic’s CEO puts numbers on frontier training costs and AGI, then hands the mic to the people who shape Claude’s character and look inside its weights.Models & trainingSafety & governanceScaling Laws+3
44:30EN
No Priors: AI, Machine Learning, Tech, & Startups· Oct 24, 2024Podcast · 2 speakers100,000 Rides a Week, Six Times Fewer Airbag Crashes: Waymo’s Co-CEO on Eighteen Years of Full AutonomyHost Sarah Guo, Elad GilDmitri Dolgov tells No Priors how a dozen Googlers, ten 100-mile routes, and a 2013 refusal to settle for driver assist became a rider-only service with an insurer-audited safety record.Infrastructure & deploymentAutonomous DrivingSafety & governance+3
37:47EN
No Priors: AI, Machine Learning, Tech, & Startups· Aug 30, 2024Podcast · 2 speakersWorking Backwards from AGI: Magic's Five-Million-Token BetHost Sarah Guo, Elad GilEric Steinberger wants a coding colleague you trust like a teammate — and a world that is still a good place thirty years after AGI.Coding agentsContext engineeringInference+3
2:15:39EN
Lex Fridman· Jun 2, 2024Podcast · 2 speakersRoman Yampolskiy Puts Superintelligent Ruin at 99.99 PercentGuest Roman Yampolskiy · Host Lex FridmanThe AI safety researcher tells Lex Fridman that controlling AGI is as impossible as a perpetual motion machine, and that tests, open source, and regulation cannot close the gap.Security & safetySafety & governanceExistential Risk+3
31:24EN
No Priors: AI, Machine Learning, Tech, & Startups· Apr 25, 2024Podcast · 2 speakersSora's Leads: A Minute of HD Video Is Just the GPT-1 of Video ModelsHost Sarah Guo, Elad GilAditya Ramesh, Tim Brooks, and Bill Peebles tell No Priors why text-to-video sits on the path to AGI, why they started from scratch instead of extending an image generator, and why they still have no product date.Multimodal & mediaVision & videoWorld models+3
3:07:27EN
Lex Fridman· Mar 22, 2024Podcast · 2 speakersFive Billion Dead, and One Person Has Six MinutesGuest Annie Jacobsen · Host Lex FridmanAnnie Jacobsen walks Lex Fridman from a second-by-second nuclear exchange to CIA secrecy, Area 51, and why she still wants the word “could” kept in the sentence.Security & safetyExistential RiskGeopolitics+1
1:55:10EN
Lex Fridman· Mar 18, 2024Podcast · 2 speakersSam Altman Expects the Road to AGI to Be a Power StruggleGuest Sam Altman · Host Lex FridmanOn a Friday afternoon in November 2023, OpenAI's board fired its CEO. Four and a half days later he was back, still refusing super-voting control.Enterprise & strategyCompany BuildingAI Strategy+3
19:10EN
No Priors: AI, Machine Learning, Tech, & Startups· Jan 11, 2024Podcast · 2 speakersThe World's Only Capped-Profit CompanyHost Sarah Guo, Elad GilNo Priors looks back at 2023 through eight conversations on money, intelligence, jobs, and who should put the guardrails on a model.Enterprise & strategyAI StrategyCompany Building+3
2:53:09EN
Lex Fridman· Dec 29, 2023Podcast · 2 speakersFear is the civilization killer: Guillaume Verdon on e/acc, thermodynamics, and being unmaskedGuest Guillaume Verdon · Host Lex FridmanThe physicist behind BasedBeffJezos tells Lex Fridman why out-of-equilibrium thermodynamics, anonymity, and a meme movement are his answer to AI deceleration.Enterprise & strategyAGISafety & governance+3
32:57EN
No Priors: AI, Machine Learning, Tech, & Startups· Nov 9, 2023Podcast · 2 speakersA 7-billion-parameter model on a MacBook: Mistral's CEO reruns the cost of AIHost Sarah Guo, Elad GilArthur Mensch tells No Priors why Chinchilla made small models valuable, why open-sourcing Mistral 7B is not a bioweapon risk, and why guardrails belong on the application.Open source & communityOpen-source ecosystemsOpen-weight models+3
41:58EN
No Priors: AI, Machine Learning, Tech, & Startups· Nov 2, 2023Podcast · 2 speakersReliability is the bottleneck. Autonomy is what would make AI feel alive.Host Sarah Guo, Elad GilIlya Sutskever talks with Sarah Guo and Elad Gil about AlexNet, OpenAI’s capped-profit bet, why smaller models mainly lose reliability, and the line he draws for digital life.Models & trainingAGIScaling Laws+3
32:34EN
No Priors: AI, Machine Learning, Tech, & Startups· Oct 23, 2023Podcast · 2 speakersTen Thousand Certified Engineers in a Year: Google Cloud's Order of Operations for Enterprise AIHost Sarah Guo, Elad GilKawal Gandhi, head of generative AI in Google Cloud's Office of the CTO, walks Sarah Guo and Elad Gil through dogfooding, the efficiency-productivity-creativity ladder, and why customer weights are the IP that cannot leak.Enterprise & strategyEnterprise AIAI Strategy+3
47:42EN
No Priors: AI, Machine Learning, Tech, & Startups· Aug 17, 2023Podcast · 2 speakersSal Khan Thinks Every Child Can Finally Have a TutorHost Sarah Guo, Elad GilThe Khan Academy founder tells Sarah Guo and Elad Gil how a family tutoring side project became an AI teaching assistant, and why he believes education is on the cusp of its biggest positive shift.Product & UXHuman-AI CollaborationSafety & governance+3
2:44:47EN
Lex Fridman· Jul 17, 2023Podcast · 2 speakersThe Next Machines Will Steal Intimacy, Not Just AttentionGuest Yuval Noah Harari · Host Lex FridmanHistorian Yuval Noah Harari tells Lex Fridman how stories built civilization, why fascism looks beautiful in the mirror, and why AI is the first tool that takes power away from humans.PhilosophySafety & governanceGeopolitics+3
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