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40:44ENGrant Sanderson: There's never been a better time to go into mathGrant Sanderson, Constantin Kogler · 3Blue1BrownStudents fear AI has solved mathematics. Grant Sanderson argues the opposite: even if machines prove theorems better than we do, the institution of math stays valuable—and this is a rare moment when newcomers can reshape it.
13:12ENAlexandra Lato on Building Stack Overflow for Agents and Stack Internal with CodexAarti Bagul, Alexandra Lato · OpenAIStack Overflow’s VP of Product explains how a small team used Codex with opposite constraints on two products—and why agent-native design means letting agents contribute knowledge, not just read it.
1:05:45ENCyrus Omar on Live Programming and a Computational Commons for Humans and AICyrus OmarA demonstration of Hazel shows how immediate feedback, structured collaboration and carefully scoped permissions could support people and AI agents working together.
2:34:18ENZeng Ming on AI’s New Era: Why Great Companies and New Organizations EmergeGuest Zeng Ming · Host 张小珺Zeng Ming argues that AI is changing the foundations of business: models will become infrastructure, while new Agent-native applications and organizations create the next wave of value. His advice to founders is to embrace uncertainty, rethink strategy continuously, and build around meaningful work rather than inherited structures.
46:08ENComputers Beat Humans at Chess 30 Years Ago. Chess.com Still Has 250 Million PlayersHost Sarah Guo, Elad GilChess.com CEO Erik Allebest tells Sarah Guo how a $56,000 domain became a $200 million business, and why superhuman AI made chess more popular, not obsolete.
36:58ENSTaR's Author Wants Models With EQ, Not Just More IQHost Sarah Guo, Elad GilEric Zelikman, the Stanford and xAI researcher behind STaR and Quiet-STaR, launches humans& on the bet that three years of IQ scaling left models emotionally unintelligent.
1:01:49ENTwo Academic Hours a Day, and 96 Percent of Kids Say They Love SchoolHost Sarah Guo, Elad GilTrilogy founder Joe Liemandt, now principal of Alpha School, tells No Priors how an AI tutor, a two-hour bargain with fifth graders, and a sports-coach ethos are meant to scale to a billion children.
1:01:23ENWill Crichton on Making Rust More UnderstandableWill Crichton · Brown UniversityOwnership visualizations, interactive trait diagnostics and program slicing illustrate an evidence-based approach to developer tools.
6:08:48ENNobody Serious Believes Cookie Banners Help AnyoneGuest DHH · Host Lex FridmanLex Fridman talks with David Heinemeier Hansson for six hours about Ruby, Rails, AI, leaving the cloud, Apple's App Store, and why a small company can still refuse other people's money.
31:03EN21 Ways to Use AI for Coding, Research and Everyday TasksMatthew Berman, Alex · Forward FutureMatthew Berman and editor Alex demonstrate AI workflows for documents, creative work, decisions, travel and reminders.
0:57ENSundar Pichai on Preparing for AI in Knowledge WorkMatthew Berman, Sundar Pichai · Forward FutureIn a short interview clip, Google's CEO suggests learning to use AI as an everyday assistant while work changes.
0:49ENSundar Pichai on AI Glasses and Project Astra’s MemorySundar Pichai · GoogleGoogle’s CEO discusses why glasses fit everyday AI interaction and describes testing Astra’s memory of an object.
47:18ENThomas Dohmke on GitHub Copilot, Coding Agents, and the Future of SoftwareMatthew Berman, Thomas Dohmke · Forward FutureGitHub’s then-CEO explains how Copilot grew from code completion into agent workflows, why programming education still matters, and where he expects human review to remain essential.
32:15ENThe Hardest Part of Learning Is Getting Yourself to StartHost Sarah Guo, Elad GilDuolingo CEO Luis von Ahn tells Sarah Guo how two-minute lessons, streaks, an 83 percent accuracy target, and large language models turned language study into a consumer product.
41:52ENMercor Hit $100 Million ARR Teaching Models to Hire. Humans Now Write the Exams.Host Sarah Guo, Elad GilBrendan Foody tells Sarah Guo and Elad Gil how Mercor automated recruiting for frontier labs — and why building evals may become the world's most common knowledge job.
35:14ENRobots Have No Wikipedia. Chelsea Finn Is Starting With Three Buildings.Host Sarah Guo, Elad GilPhysical Intelligence’s cofounder tells No Priors why a generalist robot model has to be trained across embodiments, why open-sourcing hardware is a bet against the problem going unsolved, and why humanoids are a little overrated.
1:06:43ENDaniel Dines on Why AI Agents Need Workflow AutomationGuest Daniel Dines · Host Harry StebbingsThe UiPath founder explains why he expects rule-based automation, agents and human validation to coexist—and reflects on the demands of leading through an AI transition.
8:37:34ENThe first Neuralink patient beat a world record with most of his electrodes goneGuest Elon Musk · Host Lex FridmanLex Fridman talks with Elon Musk, the Neuralink team, and Noland Arbaugh about a wireless brain implant, the software that rescued it, and why bandwidth is Musk’s bet on living with AI.
29:28ENDevin Will Not Replace Engineers. It Will Multiply Them, Says Cognition’s Scott WuHost Sarah Guo, Elad GilThe IOI champion behind Devin explains why an AI software engineer that you can watch over the shoulder creates more human engineers, not fewer.
38:01ENHalf of GDP Is Labor. Figure Wants Humanoids to Do the Work.Host Sarah Guo, Elad GilBrett Adcock tells No Priors why a 21-month-old company raised $675 million to put general-purpose humanoid robots in factories first, then homes.
54:06ENBryan Johnson on New Ideas, Longevity and Algorithmic DecisionsGuest Bryan Johnson · Host Harry StebbingsThe Blueprint founder explains his survival-centered philosophy and personal routines, while Harry Stebbings questions uncertainty, consent and social consequences.
36:31ENFigma's One-Way Door Swung Open — With a Billion-Dollar ConsolationHost Sarah Guo, Elad GilAfter regulators killed the Adobe deal, Dylan Field tells No Priors how Figma kept building, where AI belongs in design, and why the company was never meant to be only a design tool.
1:04:38ENHundreds of Miles Apart, Zuckerberg and Fridman Sat Close Enough to See the WrinklesGuest Mark Zuckerberg · Host Lex FridmanLex Fridman sat in a dark room in Austin wearing a Quest headset; Mark Zuckerberg sat in another conference room, also wearing one, and it did not feel like a video call.
47:42ENSal Khan Thinks Every Child Can Finally Have a TutorHost Sarah Guo, Elad GilThe Khan Academy founder tells Sarah Guo and Elad Gil how a family tutoring side project became an AI teaching assistant, and why he believes education is on the cusp of its biggest positive shift.
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