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39:23EN
No Priors: AI, Machine Learning, Tech, & Startups· Oct 15, 2026Podcast · 2 speakersThe Defenders' Window: Greg Brockman on AI-Generated Knowledge, Drug Discovery, and the New Physics of CybersecurityHost Sarah Guo, Elad GilOpenAI's president explains why solving open math problems is a proof point for science, how proactive agents change product form, and why security spending must exceed software spending.
41:09ENNo Priors: AI, Machine Learning, Tech, & Startups· May 28, 2026Podcast · 2 speakersAfter Agents Leak Tokens and Wipe Databases, Onyx Trains Small Models to Watch the Big OnesHost Sarah Guo, Elad GilTwo years ago enterprise security buyers told Maxim Bar Kogan he was too early. Now Fortune 10 companies are calling a sub-100-person Israeli startup because they cannot stop agent adoption — only reduce the chance the next action is illegitimate.
36:24ENNo Priors: AI, Machine Learning, Tech, & Startups· Mar 5, 2025Podcast · 2 speakersThe Man Behind Humanity's Last Exam Says Superintelligence Strategy Should Copy NukesHost Sarah Guo, Elad GilDan Hendrycks tells No Priors that labs can only do basic anti-terror refusals, while the real risk-management problem is a geopolitical deterrent he calls mutually assured AI malfunction.
2:15:39EN
Lex Fridman· Jun 2, 2024Podcast · 2 speakersRoman Yampolskiy Puts Superintelligent Ruin at 99.99 PercentGuest Roman Yampolskiy · Host Lex FridmanThe AI safety researcher tells Lex Fridman that controlling AGI is as impossible as a perpetual motion machine, and that tests, open source, and regulation cannot close the gap.
3:07:27ENLex Fridman· Mar 22, 2024Podcast · 2 speakersFive Billion Dead, and One Person Has Six MinutesGuest Annie Jacobsen · Host Lex FridmanAnnie Jacobsen walks Lex Fridman from a second-by-second nuclear exchange to CIA secrecy, Area 51, and why she still wants the word “could” kept in the sentence.
36:22ENNo Priors: AI, Machine Learning, Tech, & Startups· Oct 26, 2023Podcast · 2 speakersOne Attacker and a For Loop: Why Email Is Still the Softest Target in an AI Arms RaceHost Sarah Guo, Elad GilMaterial Security co-founder Ryan Noon on how 2016 election hacks, Google and Microsoft's email duopoly, and large language models are rewriting both sides of cybersecurity.
2:48:12ENLex Fridman· Apr 13, 2023Podcast · 2 speakersThe Asteroid We Are Building OurselvesGuest Max Tegmark · Host Lex FridmanPhysicist Max Tegmark tells Lex Fridman why a six-month pause on models larger than GPT-4 is not a ban on AI, but a chance to stop a suicide race.
3:17:51ENLex Fridman· Mar 30, 2023Podcast · 2 speakersWhoops is the sound of getting less wrong: Yudkowsky, two weeks after GPT-4Guest Eliezer Yudkowsky · Host Lex FridmanTwo weeks after GPT-4 launched, Eliezer Yudkowsky sat down with Lex Fridman and started by admitting the transformer stack had already gone further than he expected.
2:56:02ENLex Fridman· Nov 22, 2022Podcast · 2 speakersThe FBI Never Cracked a Password the Day They Took Silk RoadGuest Chris Tarbell · Host Lex FridmanFormer agent Chris Tarbell tells Lex Fridman how a timezone setting, a Gmail address, and an undercover admin brought down Ross Ulbricht — and why the best hackers are still out there.
3:35:40ENLex Fridman· Aug 24, 2022Podcast · 2 speakersLiv Boeree on Moloch, Useful Fictions, and Why Luck Keeps Poker AliveGuest Liv Boeree · Host Lex FridmanThe poker champion and science educator talks with Lex Fridman about game theory, attention, simulation, aliens, and the existential races that look like games nobody can quit.
3:53:09ENLex Fridman· Aug 8, 2022Podcast · 2 speakersThe CIA Serves One Customer, and That Customer Is the PresidentGuest Andrew Bustamante · Host Lex FridmanFormer covert officer Andrew Bustamante walks Lex Fridman through how American intelligence actually works — from the President's Daily Brief to Ukraine, Snowden, and a bar wall in Alabama.
3:47:25ENLex Fridman· Mar 27, 2022Podcast · 2 speakersThe Original Internet Godfather Built Trust Among CybercriminalsGuest Brett Johnson · Host Lex FridmanLex Fridman talks with Brett Johnson about ShadowCrew, social engineering, prison, and why most attacks still use holes everyone already knows about.
2:01:35ENLex Fridman· Feb 20, 2022Podcast · 2 speakersA no-click iPhone exploit sold for $2.5 million. Silence was the only condition.Guest Nicole Perlroth · Host Lex FridmanNicole Perlroth tells Lex Fridman how zero-days, ransomware, and a privately owned power grid turned curiosity into everyday cyberwar.
2:31:48ENLex Fridman· Dec 28, 2021Podcast · 2 speakersA Car That Cannot Drive Itself Will Be About as Useful as a HorseGuest Elon Musk · Host Lex FridmanIn a Lex Fridman conversation built around Tesla Autopilot, Elon Musk argues that every driver input is an error, that today’s hardware is already enough for full self-driving, and that watching the human will soon matter less than making the system safer than a person.
2:59:12ENLex Fridman· Jun 20, 2021Podcast · 2 speakersNature Never Dealt This CardGuest Rob Reid · Host Lex FridmanIn 2011 two labs independently engineered H5N1 so it could travel through the air between mammals — work Rob Reid tells Lex Fridman should never have been done, and still has not been stopped.
4:15:19ENLex Fridman· Jun 14, 2021Podcast · 2 speakersExponential tools, Stone Age game theoryGuest Daniel Schmachtenberger · Host Lex FridmanDaniel Schmachtenberger tells Lex Fridman why every leap in physical technology breaks the last social operating system — and why Bretton Woods cannot bind what comes next.
1:53:41ENLex Fridman· Mar 15, 2021Podcast · 2 speakersSilvio Micali: Money Is a Shared Belief, and a Blockchain Makes It Common KnowledgeGuest Silvio Micali · Host Lex FridmanThe Turing Award cryptographer and Algorand founder tells Lex Fridman why ledgers, lotteries, and one-way functions matter more than mining.
3:02:43ENLex Fridman· Jan 18, 2021Podcast · 2 speakersHumanity Cannot Survive on the Right Person Showing Up at the Right TimeGuest Max Tegmark · Host Lex FridmanMIT physicist Max Tegmark tells Lex Fridman why AI should be as well understood as rockets, why 2020 was a warning on weapons and news, and why luck is a terrible long-term plan.
2:12:36ENLex Fridman· May 12, 2020Podcast · 2 speakersAttacks Climb the Stack Until They Land on PeopleGuest Dawn Song · Host Lex FridmanDawn Song tells Lex Fridman why the next security crisis is human, how a sticker can rewrite a stop sign, and why data still has no property right.
1:39:57ENLex Fridman· Jan 17, 2020Podcast · 2 speakersPeople Say They Want Perfect Robots. They Trust the Ones That Push BackGuest Ayanna Howard · Host Lex FridmanAyanna Howard on human-robot interaction, the ethics of safety-critical code, and why a little imperfection is what actually earns trust.
1:48:55ENLex Fridman· Nov 19, 2019Podcast · 2 speakersThree Fairness Rules That Cannot All Be TrueGuest Michael Kearns · Host Lex FridmanMichael Kearns tells Lex Fridman why algorithmic fairness is messier than privacy, and why a Pareto curve belongs in front of the people who actually have to choose.
36:10ENLex Fridman· Nov 12, 2019Podcast · 2 speakersSo You're Saying There's a Chance: Musk on Neuralink, AI, and a Pale Blue DotGuest Elon Musk · Host Lex FridmanLex Fridman and Elon Musk move from consciousness and an AI referee to the engineering of a brain implant, Tesla Autopilot, and Carl Sagan's lonely speck.
1:13:06ENLex Fridman· Aug 19, 2019Podcast · 2 speakersLockheed Martin's CTO on Autonomy, the Moon, and the Culture of Not Getting It WrongGuest Keoki Jackson · Host Lex FridmanKeoki Jackson tells Lex Fridman why going back to the Moon is the easy part—and why proving a learning system will still do the right thing is not.
32:45ENLex Fridman· Apr 12, 2019Podcast · 2 speakersElon Musk: Every Driver Input Is an Error Tesla Autopilot Must EliminateGuest Elon Musk · Host Lex FridmanAfter MIT published a study of functional vigilance on Autopilot, Lex Fridman sat down with Musk to argue about cameras on drivers, fleet data, and whether humans still belong in the loop.Load moreShowing 24 of 31