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38:14EN
No Priors: AI, Machine Learning, Tech, & Startups· Sep 18, 2026Podcast · 2 speakersDiffusion Will Win Inference: Stefano Ermon Bets Parallel Tokens Beat Custom SiliconHost Sarah Guo, Elad GilThe Stanford diffusion pioneer tells No Priors why a 50-person lab is training language models that generate many tokens at once — and why that maps to GPUs the way transformers once mapped to training.Models & trainingInferenceAI cost & performance+3
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No Priors: AI, Machine Learning, Tech, & Startups· Oct 9, 2025Podcast · 2 speakersSTaR's Author Wants Models With EQ, Not Just More IQHost Sarah Guo, Elad GilEric Zelikman, the Stanford and xAI researcher behind STaR and Quiet-STaR, launches humans& on the bet that three years of IQ scaling left models emotionally unintelligent.Models & trainingPost-trainingReinforcement Learning+3
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No Priors: AI, Machine Learning, Tech, & Startups· May 1, 2025Podcast · 2 speakerso3 should wait exactly as long as the answer takesHost Sarah Guo, Elad GilOpenAI researchers Eric Mitchell and Brandon McKinzie tell No Priors why o3's leap is a chain of tools during reasoning — and why you should send the same prompt a hundred times.Models & trainingReasoning & test-time computeReinforcement Learning+3
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No Priors: AI, Machine Learning, Tech, & Startups· Mar 20, 2025Podcast · 2 speakersRobots Have No Wikipedia. Chelsea Finn Is Starting With Three Buildings.Host Sarah Guo, Elad GilPhysical Intelligence’s cofounder tells No Priors why a generalist robot model has to be trained across embodiments, why open-sourcing hardware is a bet against the problem going unsolved, and why humanoids are a little overrated.Models & trainingRoboticsData quality & curation+3
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No Priors: AI, Machine Learning, Tech, & Startups· Feb 25, 2025Podcast · 2 speakersA Hundred Million Cells, Four People, Three Days: Biology's ImageNet MomentHost Sarah Guo, Elad GilVevo Therapeutics and the Arc Institute open-sourced Tahoe-100M and a 230-million-cell atlas in the same week — and argued that virtual cells, not just protein folders, are the next language model of biology.Models & trainingAI for scienceData quality & curation+3
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No Priors: AI, Machine Learning, Tech, & Startups· Aug 1, 2024Podcast · 2 speakersOriol Vinyals: The Days of Burning 90% of Compute on Pretraining Are NumberedHost Sarah Guo, Elad GilGoogle DeepMind’s VP of research on Gemini, long context, the coming shift from pretraining to RL, and why AGI may never have a finish line.Models & trainingAGI TimelinesPretraining & midtraining+3
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No Priors: AI, Machine Learning, Tech, & Startups· Jun 27, 2024Podcast · 2 speakersFive Independent Teams Found the Same 10-to-1 Mix That Beats TransformersHost Sarah Guo, Elad GilThe authors of S4 and Mamba argue that mostly state-space layers plus a dash of attention is the architecture that actually works—and they are shipping it first as real-time speech.Models & trainingTransformers & attentionVoice AI+3
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No Priors: AI, Machine Learning, Tech, & Startups· Jan 25, 2024Podcast · 2 speakers99% of Factory Robots Are Dumb. Covariant Wants the Smart Ones Working in Warehouses FirstHost Sarah Guo, Elad GilFormer OpenAI researcher Peter Chen explains why robot foundation models have to be trained on production floors, not in labs.Models & trainingRoboticsFoundation Models+3
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No Priors: AI, Machine Learning, Tech, & Startups· Nov 2, 2023Podcast · 2 speakersReliability is the bottleneck. Autonomy is what would make AI feel alive.Host Sarah Guo, Elad GilIlya Sutskever talks with Sarah Guo and Elad Gil about AlexNet, OpenAI’s capped-profit bet, why smaller models mainly lose reliability, and the line he draws for digital life.Models & trainingAGIScaling Laws+3
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No Priors: AI, Machine Learning, Tech, & Startups· Sep 28, 2023Podcast · 2 speakersDNA Is Code, but You Compile It with a PipetteHost Sarah Guo, Elad GilGinkgo Bioworks CEO Jason Kelly tells No Priors why cells are worth the magic, why biology has no AWS, and why a pandemic should look like cybersecurity.Models & trainingAI for scienceBiosecurity+3
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No Priors: AI, Machine Learning, Tech, & Startups· Aug 24, 2023Podcast · 2 speakersThe Author of Attention Is All You Need Now Compiles mRNA Like BytecodeHost Sarah Guo, Elad GilJakob Uszkoreit on why Transformers won, why models spend compute on the wrong things, and why drug discovery has to become generation rather than screening.Models & trainingAI for scienceTransformers & attention+2
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No Priors: AI, Machine Learning, Tech, & Startups· May 18, 2023Podcast · 2 speakersTen Percent of Search Is Health — and the Doctor Is Googling TooHost Sarah Guo, Elad GilGoogle researcher Karan Singhal on Med-PaLM 2, the real bar for medical language models, and why medicine is a harder alignment lab than chatbots.Models & trainingAI in healthcareSafety & governance+3
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No Priors: AI, Machine Learning, Tech, & Startups· Apr 6, 2023Podcast · 2 speakersA 6-Billion-Parameter Clone of ChatGPT’s Core TrickHost Sarah Guo, Elad GilDatabricks CTO Matei Zaharia tells Sarah Guo and Elad Gil how Dolly learned instruction-following on fifty times less data than GPT-3 — and why he would rather look facts up than bake them into a trillion-parameter network.Models & trainingOpen-weight modelsFine-tuning+3
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No Priors: AI, Machine Learning, Tech, & StartupsPodcast · 2 speakersBiohub's Bet: Building Open AI World Models of Biology From Proteins Up to CellsHost Sarah Guo, Elad GilMark Zuckerberg, Priscilla Chan and Alex Rives explain why Biohub pairs a frontier AI lab with frontier wet-lab biology, and why it releases tools like ESMFold2 as open source.Models & trainingAI for scienceOpen-source ecosystems+3