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35:39EN
No Priors: AI, Machine Learning, Tech, & Startups· Oct 2, 2026Podcast · 2 speakersCompute Scaled a Millionfold. Bandwidth Only 40x. Fractile Wants to Fix That RatioHost Sarah Guo, Elad GilIn the summer of 2022, Walter Goodwin founded Fractile in London to build very fast inference chips for the world's largest models.
47:22EN
Sequoia Capital· Aug 4, 2026PodcastFrom One in a Thousand to 15 Percent: Chai Discovery Treats Drug Design as a Scaling ProblemJoshua Meier and Matthew McPartlon tell Sequoia’s Training Data why antibody design is an engineering problem, not a bespoke science, and why they sell a molecular CAD suite instead of their own drugs.
49:12ENSequoia Capital· Jul 29, 2026PodcastThe People Writing the Transformer’s Eulogy Want a Lab That Can Take Vacation Without Themo1’s reasoning lead and a Gemini pre-training lead argue the architecture, not more scale, is now the bottleneck — and that replacing it starts with automating kernel generation.
1:47:38EN
Cognitive Revolution "How AI Changes Everything"· Jul 4, 2026Podcast19 Neurons Can Drive a Car. Liquid AI Wants Foundation Models on Every ChipHost Nathan LabenzRamin Hasani traces liquid neural networks from a worm's 300-cell brain to a 600-megabyte model that will talk from inside a Mercedes, and explains why architecture search now beats architecture avengers.
1:13:33EN
Unsupervised Learning: With Jacob Effron· Jun 3, 2026PodcastA Trillion Tokens Later, the Concept Finally Lands: Łukasz Kaiser on What Transformers Still MissHost Jacob EffronThe Attention Is All You Need co-author tells Unsupervised Learning that transformers will probably keep winning — and that they still do not learn the way people do.
2:25:58EN
Lex Fridman· Mar 23, 2026Podcast · 2 speakersAGI Is Already Here. Building NVIDIA Is Not.Guest Jensen Huang · Host Lex FridmanLex Fridman sits down with Jensen Huang for two and a half hours on extreme co-design, CUDA, four scaling laws, and why a $1 billion AI company is easier than a durable one.
4:25:13ENLex Fridman· Jan 31, 2026PodcastThe Architecture Barely Changed. Data, Cost, and Open Weights Did.Host Lex FridmanNathan Lambert and Sebastian Raschka walk Lex Fridman through a year in which training methods and datasets moved more than model design, and 2026 looks like a fight over inference cost, agents, and who owns truly open models.
1:03:00ENUnsupervised Learning: With Jacob Effron· Jan 29, 2026PodcastA Model That Solves New Math Problems Every Week Still Isn't AGIHost Jacob EffronFormer OpenAI research VP Jerry Tworek on why scaling still works, why models go hopeless when they fail, and why he left to chase continual learning.
37:00ENSequoia Capital· Jan 14, 2026PodcastThe AlphaChip Team That Laid Out Four TPUs Now Wants Every Company to Be DesignlessAnna Goldie and Azalia Mirhoseini tell Sequoia how an RL floorplanner survived TPU-team anger, learned to draw donut-shaped macros, and became a bet that AI will design chips that then feed AI.
1:18:05ENUnsupervised Learning: With Jacob Effron· Dec 18, 2025PodcastThe Real Bottleneck in AI Research Is Compute, Not IdeasHost Jacob EffronAfter NeurIPS, Ari Morcos and Rob Toews sit down with Jacob Effron to argue about plateauing models, SSI’s secrecy, OpenAI’s cash burn, and a set of spicy 2026 bets.
39:16ENNo Priors: AI, Machine Learning, Tech, & Startups· Nov 19, 2025Podcast · 2 speakers500 Gloves, 10 Million Trajectories, and a $10,000 Home RobotHost Sarah Guo, Elad GilSunday Robotics co-founders Tony Zhao and Cheng Chi map the gap between a scalable imitation-learning recipe and a machine that actually does the dishes.
1:39:05ENCognitive Revolution "How AI Changes Everything"· Oct 29, 2025PodcastThe Summer GPT-5 Disappointed Does Not Mean AI Progress Has StalledHost Nathan LabenzNathan Labenz tells Erik Torenberg why the GPT-5 backlash mixed up product mishaps, naming chaos, and a real jump in capabilities.
41:32ENSequoia Capital· Oct 28, 2025PodcastMoore's Law Is Slowing. Nvidia's CTO Still Wants 10× a YearMichael Kagan on why Nvidia's $7 billion Mellanox deal, not just more transistors, is how you turn a data center into one computer.
1:02:05ENUnsupervised Learning: With Jacob Effron· Sep 24, 2025Podcast$100 Million Researchers and a $200 Billion xAI: An AI Roundtable Does the MathHost Jacob EffronDatology’s Ari Morcos and Radical Ventures’ Rob Toews argue over whether models are plateauing, whether RL-environment startups will last, and why Google is the lab they would pick.
2:12:04ENLex Fridman· Jun 5, 2025Podcast · 2 speakersFrom a Five-Year Phone Queue to 480 Trillion Tokens a MonthGuest Sundar Pichai · Host Lex FridmanSundar Pichai talks with Lex Fridman about Chennai, the AI package, Search, Chrome, Waymo, and why he stayed calm when the headlines said Google was finished.
51:08ENUnsupervised Learning: With Jacob Effron· Apr 15, 2025PodcastThe Transformer Co-Author Who Says Scaling Hit a WallHost Jacob EffronCohere CEO Aidan Gomez tells Redpoint that a $100 million model is still an amnesiac genius, and that enterprise AI money is concentrating in support, research, and the back office.
1:10:23ENUnsupervised Learning: With Jacob Effron· Mar 17, 2025PodcastA Million Tokens per Dollar: Why Noam Shazeer Thinks Inference Compute Is Still UntappedHost Jacob EffronThe Transformer co-inventor and Gemini researcher Jack Rae walk through test-time compute, Ilya Sutskever's AGI critique, and a four-year-old who now lectures his teacher about lizards.
57:41ENNo Priors: AI, Machine Learning, Tech, & Startups· Feb 25, 2025Podcast · 2 speakersA Hundred Million Cells, Four People, Three Days: Biology's ImageNet MomentHost Sarah Guo, Elad GilVevo Therapeutics and the Arc Institute open-sourced Tahoe-100M and a 230-million-cell atlas in the same week — and argued that virtual cells, not just protein folders, are the next language model of biology.
48:18ENUnsupervised Learning: With Jacob Effron· Dec 6, 2024PodcastNoam Brown: There's No Hard Wall—Just Eight Orders of Magnitude of HeadroomHost Jacob EffronA ChatGPT query costs about a penny. The problems society cares about most, he says, are worth a million dollars.
44:16ENNo Priors: AI, Machine Learning, Tech, & Startups· Nov 21, 2024Podcast · 2 speakersCohere's Aidan Gomez: The Model Curve Is Flattening, and $20 Million Now Buys GPT-4Host Sarah Guo, Elad GilThe Attention Is All You Need co-author tells No Priors why enterprises should stop waiting for the next model and start putting today's models into production.
2:40:58ENCognitive Revolution "How AI Changes Everything"· Nov 16, 2024PodcastZvi Mowshowitz Still Puts P(doom) at 60%—and Says Not Updating Is Self-DeceptionHost Nathan LabenzA six-month recap with the Don't Worry About the Vase author covering Ilya’s SSI, OpenAI’s o1, Claude’s computer use, the SB 1047 veto, and Trump’s return.
5:15:00ENLex Fridman· Nov 11, 2024Podcast · 2 speakersDario Amodei Has Seen This Scaling Movie Enough TimesGuest Dario Amodei · Host Lex FridmanAnthropic’s CEO puts numbers on frontier training costs and AGI, then hands the mic to the people who shape Claude’s character and look inside its weights.
36:49ENNo Priors: AI, Machine Learning, Tech, & Startups· Nov 7, 2024Podcast · 2 speakersJensen Huang: NVIDIA Is No Longer Building Computers. It Is Building AI FactoriesHost Sarah Guo, Elad GilOn No Priors, NVIDIA’s CEO walks through hyper Moore’s law, NVLink, a 100,000-GPU cluster stood up in weeks, and why tokens are the new commodity.
41:42ENSequoia Capital· Oct 22, 2024PodcastNeural Networks Are Still Waiting for Their ThermodynamicsOpenAI researcher Dan Roberts on why physicists keep migrating into AI, and why the field still lacks the equivalent of the ideal gas law.Load moreShowing 24 of 53