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15:41ENAbolishing Involuntary Death: Ben Goertzel on Immortality, Pain and the Meaning of LifeHost Lex FridmanIn a clip from Lex Fridman's podcast, AI researcher Ben Goertzel argues that death and pain should be optional, and sketches what it would take to fund a serious attack on aging.
58:12ENProduct Management in a Newsroom: Equanimity, Dress Rehearsals and Journalists as CustomersGuest Upasna Gautam · Host Lenny RachitskyCNN product manager Upasna Gautam explains how her team builds a content management system for journalists amid constant breaking news, and how mindfulness shapes the way she leads.
1:07:32ENMinimal Lovable Products, the Airbnb Plus Post-Mortem, and the Trust Bank: Product Lessons from Jiaona ZhangHost Lenny RachitskyWebflow's SVP of Product on the mistakes new PMs make, why Airbnb Plus never had a path, roadmap-as-story, OKRs that stretch instead of sandbag, surviving WeWork, and how to spend your first 90 days.
1:32:32ENDevin's Scott Wu on Building an AI Software Engineer and Turning Coders into ArchitectsGuest Scott Wu · Host Lenny RachitskyThe Cognition co-founder explains how his 15-person team uses fleets of Devins to build Devin, what the product can and can't do, and why he expects more engineers, not fewer.
55:48ENWhen to Invent a Category, and How Miro Rebranded Itself into OneGuest Barbra Gago · Host Lenny RachitskyFormer Miro CMO Barbra Gago explains how category creation, a rushed rebrand and opinionated software work in practice.
1:31:52ENFrom Phonemes to CTC: How Deep Learning Rebuilt Speech RecognitionHost Lex FridmanBaidu's Adam Coates walks through the traditional speech pipeline, the CTC-based end-to-end engine that replaced much of it, and what it takes to scale and deploy it.
1:25:11ENInside Miro's Product Machine: Empathy, Competition and a Biweekly Demo Party That Saved Three MonthsGuest Varun Parmar · Host Lenny RachitskyMiro chief product officer Varun Parmar walks Lenny Rachitsky through the company's product values, org design, competitive philosophy, planning cadence and growth model.
1:31:29ENLovable's Growth Playbook: Give It Away, Ship Daily and Recapture Product-Market Fit Every Three MonthsGuest Elena Verna · Host Lenny RachitskyElena Verna, head of growth at Lovable, explains why most of her 15-20 years of growth experience no longer applies to a company that passed $200 million ARR in under a year.
57:08ENShipping Finn: Intercom's Product Playbook for the ChatGPT EraHost Jacob EffronDes Traynor explains how Intercom pivoted to AI, shipped Finn, built guardrails, and turned customer support into a product lab for LLMs.
21:52ENThe Secret Seminar: Eric Weinstein on What Happens When Academia Meets Someone It Can't CategorizeHost Lex FridmanIn a clip from the Lex Fridman Podcast, mathematician Eric Weinstein recounts discovering a hidden seminar at Harvard and explains why he thinks institutions fail on novel cases.
22:31ENTen Regrets: Marty Cagan on What He Got Wrong About ProductHost Lenny RachitskyAt Lenny and Friends Summit, Marty Cagan revisits his decades of product advice and names the ten things he would change.
1:01:05ENThe Most Popular Product Lessons of the Year, From Positioning to Hard ConversationsHost Lenny RachitskyA countdown of Lenny's ten most downloaded episodes, distilled into practical lessons on positioning, analytics, growth, career leverage, product leadership, and management.
14:41ENTalking for 20 Minutes: How the Alexa Prize Turns Real Customers into a Testbed for Conversational AIGuest Rohit Prasad · Host Lex FridmanRohit Prasad, head scientist of Amazon Alexa, explains the Alexa Prize grand challenge, how it is judged and why true conversation still needs reasoning.
50:03ENCopilot Is a Copilot, Not a Pilot: Inbal Shani on the Future of AI in Software DevelopmentHost Lenny RachitskyGitHub's chief product officer explains what AI changes for developers, what it does not replace, and how teams should adopt it.
1:22:31ENPower Is a Tool: Stanford's Jeffrey Pfeffer on the Seven Rules of Getting AheadGuest Jeffrey Pfeffer · Host Lenny RachitskyStanford organizational behavior professor Jeffrey Pfeffer walks Lenny Rachitsky through the seven rules of power, the homework that makes them stick, and the price power exacts.
1:45:55ENFrom Static Structures to Moving Molecules: Where AI for Protein Design Stands After AlphaFold 3Host Nathan LabenzComputational biochemist Amelie Schreiber walks Nathan Labenz through six months of progress in structure prediction, molecular dynamics, peptide and antibody models, and early agent-driven design workflows.
46:21ENForty-Eight Miles, Twelve Thank-Yous: Lex Fridman Takes On the Goggins ChallengeHost Lex FridmanLex Fridman runs four miles every four hours for 48 hours and records a gratitude reflection after each session.
1:17:25ENDon't Trust the Process: How Design Work Is Being Rebuilt Around Engineers and AgentsHost Lenny RachitskyClaude Cowork design lead Jenny Wen explains why the classic discovery-to-mock workflow is fading, what designers do instead, and who she wants to hire.
1:47:31ENFrom Fever Dream to Wilderness: Drew Houston on Dropbox's Three ErasGuest Drew Houston · Host Lenny RachitskyDropbox's co-founder and CEO gives a candid account of explosive growth, the Google Photos shock, a painful pivot to productivity, and the personal and organizational reset that followed.
40:42ENDon't Mistake a Month of Hype for the End of SoftwareHost Sarah Guo, Elad GilSarah Guo and Elad Gil separate the SaaS-apocalypse noise from the real signals: record revenue ramps, collapsing token prices, and the question of when a founder should sell.
34:57ENIt's Six Months In: Misconceptions About AI, Regulation, Context Windows and IncumbentsHost Sarah Guo, Elad GilSarah Guo and Elad Gil answer listener questions on what the market gets wrong about generative AI, from the nuclear-regulation analogy to where startups can still beat incumbents.
2:01:57ENBuild the Sales Team Like a Founder: Jason Lemkin on Hiring, Comp and Keeping Product CloseGuest Jason Lemkin · Host Lenny RachitskySaaStr founder Jason Lemkin walks through when to hire your first reps, who to hire, how to pay them, how product and sales should work together, and why customer-hostile tactics don't compound.
1:37:47ENYou Can Patch a Bug, but You Can't Patch a Brain: Why AI Guardrails FailGuest Sander Schulhoff · Host Lenny RachitskyAdversarial-robustness researcher Sander Schulhoff explains why prompt injection and jailbreaks remain unsolved, why guardrail products don't deliver, and what teams can do instead.
2:53:45ENJoscha Bach on Seven Stages of Lucidity, Brutalist LLMs, and Why Life on Earth Isn't Only About HumansGuest Joscha Bach · Host Lex FridmanA wide-ranging conversation on how minds are built, what language models are missing, and how an AI-saturated world might change consciousness, identity and risk.
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