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14:44ENSupriya Subudhi on Five Lessons From A/B Testing AI at BumbleSupriya Subudhi · BumbleA positive test is only the start: usage, output quality, model cost and regulation all shape whether an AI feature can scale.
1:20:42ENDavid Tisch on Seed Investing, Ownership and Finding Outlier CompaniesGuest David Tisch · Host Harry StebbingsThe BoxGroup founder discusses portfolio construction, competition for seed deals and the relationships behind venture investing.
18:29ENSteven Latré on the Economics of Running Your Own AI ModelsSteven Latré · imecAn imec study compares APIs, rented GPUs and owned infrastructure for long-running coding agents.
11:39ENMinnesota Polling Charges, Brazil’s Election and the AI Investment BoomAri · PragerUThe Wrap-Up surveys charges against two activists, Flávio Bolsonaro’s departure from Brazil, technology employment and a Texas school’s tribute.
17:02ENHow Upstart Evaluates Voice Agents for Regulated Lending CallsBrooke Hopkins, Shiv Indap · CovalShiv Indap and Brooke Hopkins explain human review, LLM judges and simulation in a continuous evaluation loop.
1:20:06ENJames Smith and Chris Williamson on Success, Family and Growing UpGuest James Smith · Host Chris WilliamsonA conversation about changing ambitions, youthful mistakes and separating self-worth from performance.
25:47ENRichmond Alake on Memory and the Intelligence Plane for AI AgentsRichmond Alake · OracleOracle’s Richmond Alake proposes an intelligence plane to connect agent memory, enterprise knowledge and continual learning. He illustrates the idea with architecture diagrams and demonstrations.
18:45ENJack Woodruff on AI and the Human Work of Stock PickingVinoo Ganesh, Jack Woodruff · KeplerThe former Candlestick Capital CIO discusses research, auditable data and how AI may reshape investment teams with Kepler CEO Vinoo Ganesh.
48:45ENPaul Copplestone on Databases for AI Builders and AgentsPaul Copplestone · SupabaseThe Supabase cofounder discusses the company’s growth, personal databases, agent-friendly tools and adapting to new kinds of builders.
51:35ENKarim Lakhani on Learning, Judgment and Work with AIGuest Karim R. Lakhani · Host Marina MogilkoThe Harvard Business School professor discusses how people can work with AI without surrendering their judgment or capacity to learn.
15:27ENRayan Krishnan on Model Evaluation Beyond the Model CardRayan Krishnan · Vals AIThe Vals AI cofounder explains why task-level accuracy, total cost and company-specific evaluations can change which model is the best fit.
19:06ENWojciech Pluta on Deciding What an AI Agent Should RememberWojciech Pluta · OracleOracle’s Wojciech Pluta explains memory promotion, a mortgage-agent demonstration, and the controls needed to carry useful information across sessions.
1:25:46ENAll-In on Anthropic’s IPO, AI Infrastructure and the Midterm ElectionsHost Jason Calacanis, Chamath Palihapitiya, David Sacks, David FriedbergThe hosts analyze Anthropic’s filing, debate the costs of an AI infrastructure boom, discuss Alphabet and offer competing midterm forecasts.
52:10ENJay Madheswaran on AI and the Economics of Plaintiff LawGuest Jay Madheswaran · Host Alex RampellEve’s CEO and a16z’s Alex Rampell discuss legal labor, case economics and the role of AI in plaintiff firms.
36:59ENDennis Prager on Brazil’s Election, Political Conflict and Audience QuestionsMarissa Streit, Dennis Prager · PragerUPrager and Marissa Streit discuss elections, protests and cultural questions, then respond to listeners on family and history.
1:01:10ENRobert Caro on Power, Political Genius and a Life of ResearchGuest Robert Caro · Host Dwarkesh PatelThe biographer discusses Robert Moses, Lyndon Johnson and the discipline of investigating how power works.
49:29ENTheo on Agent Harnesses, Interfaces and Shifting AbstractionsTheo · T3 CodeThe T3 Code creator explains his model of harnesses and why he expects their differences to become less visible to users.
16:43ENIshween Kaur on Securing Agent Payments with x402Ishween Kaur · SoFiA testnet walkthrough of price changes, replay, premature delivery, lookalike sellers and prompt injection in agent payment flows.
1:12ENSOTA Wives on Founding, Marriage and Taking a ChanceHost Sarah Chieng, Vivian Midha ShenSarah Chieng and Vivian Midha Shen introduce their podcast with a candid exchange about startup bets, ambition and relationships.
2:42:18ENJoe Rogan and Legion of Skanks on Comedy, Animals and Life on the RoadGuest Big Jay Oakerson, Luis J. Gomez, Steve Rannazzisi · Host Joe RoganThe comedians trade stories about podcasting, wildlife, cars and the changing world of comedy.
52:54ENHard Fork on Anthropic’s IPO and the Week in AIGuest Erin Griffith, Mike Isaac, Jasmine Sun · Host Max ReadMax Read and guests discuss the filing, AI infrastructure, elections, cybersecurity and the changing tech workforce.
20:04ENSomtochi Onyekwere: Separate Protocol Logic from I/O for Deterministic TestsSomtochi Onyekwere · Fly.ioA Sans I/O design lets a local simulator run thousands of protocol states with virtual time and controlled failures.
17:45ENKillian Carlsen-Phelan on Guiding and Verifying Coding AgentsKillian Carlsen-Phelan · SonarSonar demonstrates how project context and deterministic checks can be incorporated into a coding agent’s workflow.
23:33ENThe Fat Electrician Recounts the Life of Logan WestonGuest The Fat Electrician · Host Chris WilliamsonChris Williamson asks the military-history creator about the “Fighting Preacher,” whose service spanned World War II, Korea and the Vietnam era.
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