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1:18:46EN
Cognitive Revolution "How AI Changes Everything"· Mar 16, 2026Podcast90 Slides in 45 Minutes: A Full-Time AI Scout Admits He Can No Longer Keep UpHost Nathan LabenzNathan Labenz’s LexLab briefing for lawyers runs through the good, the bad, and the weird of frontier models — from triplicate second opinions on his son’s cancer care to AIs that know they are being tested.
1:43:39ENCognitive Revolution "How AI Changes Everything"· Mar 11, 2026PodcastFive Mutations Could Make a 60% Fatal Bird Flu Spread Between PeopleHost Nathan LabenzJohns Hopkins assistant professor Jassi Pannu argues for locking down only the sliver of functional data that teaches models how to make pandemic viruses — and keeping the rest of biology open.
2:06:23ENCognitive Revolution "How AI Changes Everything"· Mar 8, 2026PodcastFive AI Employees Live on Five Mac MinisHost Nathan LabenzAfter selling her YC packaging company, Jesse Genet opened a terminal for the first time and built an OpenClaw staff that now plans lessons, logs learning, and keeps family evenings from sliding into slop.
1:49:53ENCognitive Revolution "How AI Changes Everything"· Mar 5, 2026PodcastDon't Fight Backprop: Goodfire's Bet on Designing What Models LearnHost Nathan LabenzDan Balsam and Tom McGrath return to The Cognitive Revolution with a $150 million Series B, a new research pillar called intentional design, and a rule for anyone who wants to steer training: stop trying to out-muscle gradient descent.
2:17:36ENCognitive Revolution "How AI Changes Everything"· Mar 1, 2026PodcastCurrent Safety Techniques Will Not Give You Many Nines—and They May Fail TogetherHost Nathan LabenzUK AISI chief scientist Geoffrey Irving on jailbreaks that never fail, correlated alignment failures, and why a government lab is funding theory.
2:03:56ENCognitive Revolution "How AI Changes Everything"· Feb 25, 2026Podcast260 Doctors and 49,000 Criteria: How OpenAI Built Attending-Level Health AIHost Nathan LabenzKaran Singhal tells Nathan Labenz how ChatGPT Health was evaluated with physicians, walled off from model training, and aimed at raising both the floor and the ceiling of human health.
54:26ENCognitive Revolution "How AI Changes Everything"· Feb 22, 2026PodcastTen Billion Active Parameters, and the Unsexy Work of Making Them Agent-ReadyHost Nathan LabenzMiniMax researcher Olive Song explains how M2 was trained with expert developers as reward models, interleaved thinking, and a perturbation pipeline that treats every scaffold change as the real generalization test.
1:34:29ENCognitive Revolution "How AI Changes Everything"· Feb 18, 2026PodcastThree IMO Golds Missed the Same Problem. Harmonic Wants Math to CompileHost Nathan LabenzVlad Tenev and Tudor Achim built Aristotle to emit Lean proofs a kernel can check—and they argue that is how mathematical superintelligence stays trustworthy.
2:25:42ENCognitive Revolution "How AI Changes Everything"· Feb 14, 2026PodcastThe experts argued through the coffee break — and never agreed whether AI can build AIHost Nathan LabenzOn a marathon Cognitive Revolution live show, a cancer-AI researcher, a former OpenAI board member, and a national-security analyst each hit a different wall in the boom.
1:34:42ENCognitive Revolution "How AI Changes Everything"· Feb 13, 2026PodcastA $500 Kernel, a Ten-Month Village, and the Temper of AgentsHost Nathan LabenzJames Zou, Sam Hammond, and Shoshannah Tekofsky on science agents, America's knowledge-work bet, and what models actually do when you leave them alone.
1:18:49ENCognitive Revolution "How AI Changes Everything"· Feb 8, 2026PodcastIf AGI Is Cheap Intelligent Labor, Cyber Defense Should Become Continuous ForensicsHost Nathan LabenzAsymmetric Security founder Alexis Carlier argues that assuming AGI means redesigning defense around proactive digital forensics instead of alert triage.
1:57:56ENCognitive Revolution "How AI Changes Everything"· Feb 5, 2026PodcastA Hundred Million Lines at Twenty Cents Each: Inside Blitzy's Enterprise Coding PipelineHost Nathan LabenzCEO Brian Elliott and CTO Sid Pardeshi tell Nathan Labenz how Blitzy turns a giant codebase into a map, then lets thousands of dynamically generated agents ship most of a multi-month project in days.
1:04:51ENCognitive Revolution "How AI Changes Everything"· Feb 1, 2026Podcast125 million cells took a decade. The next billion takes monthsHost Nathan LabenzMark Zuckerberg and Priscilla Chan on pairing a frontier biology lab with a frontier AI lab so models train on data that was designed for them.
4:25:13EN
Lex Fridman· Jan 31, 2026PodcastThe Architecture Barely Changed. Data, Cost, and Open Weights Did.Host Lex FridmanNathan Lambert and Sebastian Raschka walk Lex Fridman through a year in which training methods and datasets moved more than model design, and 2026 looks like a fight over inference cost, agents, and who owns truly open models.
1:03:00EN
Unsupervised Learning: With Jacob Effron· Jan 29, 2026PodcastA Model That Solves New Math Problems Every Week Still Isn't AGIHost Jacob EffronFormer OpenAI research VP Jerry Tworek on why scaling still works, why models go hopeless when they fail, and why he left to chase continual learning.
1:39:17ENCognitive Revolution "How AI Changes Everything"· Jan 29, 2026PodcastAI Already Beats the Median Lawyer. Top Firms Bought the Tools and Left Them UnusedHost Nathan LabenzKevin Frazier and Alan Rozenshtein walk through how frontier models are changing legal practice, why billable hours stall adoption, and which new rights and government limits they want next.
2:12:31ENCognitive Revolution "How AI Changes Everything"· Jan 25, 2026PodcastMost Caffeine users have no idea they are on a blockchainHost Nathan LabenzDFINITY's Dominic Williams tells Nathan Labenz why a tamper-proof, unstoppable cloud is the right backend for AI that writes software from a chat box.
2:25:10ENCognitive Revolution "How AI Changes Everything"· Jan 22, 2026PodcastFine-Tuning Isn't Dead — But It Turned a Helpful Model EvilHost Nathan LabenzNathan Labenz on why prompting replaced fine-tuning for most work, what emergent misalignment actually showed, and how he is thinking about jobs, UBI, and AGI.
2:29:42ENCognitive Revolution "How AI Changes Everything"· Jan 18, 2026PodcastTwelve hooks and thirty files: Daniel Miessler’s personal OS on Claude CodeHost Nathan LabenzThe PAI framework treats scaffolding, not the model, as the product — a goal-centered agent stack that Miessler thinks will decide both knowledge-work automation and the next cybersecurity race.
1:40:51ENCognitive Revolution "How AI Changes Everything"· Jan 14, 2026PodcastReasoning Models Just Made the Other 80–90% of Enterprise Data UsableHost Nathan LabenzSnowflake VP of AI Baris Gultekin on text-to-SQL, RAG, agent design, and why inference has to run next to governed data.
1:54:30ENCognitive Revolution "How AI Changes Everything"· Jan 9, 2026PodcastFrom One in Ten Cancer Cells to One in a MillionHost Nathan LabenzNathan Labenz's solo AMA updates his son's lymphoma treatment, calls Claude Opus 4.5 software AGI, and ranks the live players of early 2026.
1:55:02ENCognitive Revolution "How AI Changes Everything"· Jan 4, 2026PodcastAn Index Fund on AGI: How MATS Filters the Next 120 AI Safety ResearchersHost Nathan LabenzRyan Kidd, co-executive director of MATS, tells Nathan Labenz why he will not shout a timeline, why every safety technique is also a capabilities technique, and who actually gets hired.
1:18:40ENCognitive Revolution "How AI Changes Everything"· Jan 1, 2026PodcastWhen AI Becomes the Oil Well: Luke Drago on the Intelligence CurseHost Nathan LabenzThe Workshop Labs co-founder tells the FLI Podcast why a world of non-human production could recreate the resource curse — and how private data, open weights, and moonshot careers might still break it.
3:52:17ENLex Fridman· Dec 31, 2025PodcastSome Infinities Are Larger Than OthersHost Lex FridmanJoel David Hamkins walks Lex Fridman from Hilbert's Hotel through Gödel, the continuum hypothesis, and a set-theoretic multiverse where truth is not the same as proof.Load moreShowing 24 of 730