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3:18:09EN
Lex Fridman· Nov 30, 2025Podcast · 2 speakersA Thing Is Alive When Its Goals Outrun Its PartsGuest Michael Levin · Host Lex FridmanTufts biologist Michael Levin tells Lex Fridman that intelligence is a spectrum of persuadability, that even a bubble sort hosts unexpected goals, and that the brain is a thin client to a space physics does not own.
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No Priors: AI, Machine Learning, Tech, & Startups· Nov 13, 2025Podcast · 2 speakersA New Drug Burns $2 Billion and 10 Years. Benchling's CEO Wants AI to Cut That to ThreeHost Sarah Guo, Elad GilMost medicines fail in years seven to ten, after hundreds of millions have already gone into the clinic—and Sajith Wickramasekara thinks sending things to space may already be easier.
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Cognitive Revolution "How AI Changes Everything"· Oct 25, 2025PodcastHe Co-Wrote the Transformer Paper. Now He Wants You to Own Your AI.Host Nathan LabenzNEAR founder Illia Polosukhin maps a future of personal software, agent-run markets, and AI delegates that vote without a private agenda.
1:37:25ENCognitive Revolution "How AI Changes Everything"· Oct 5, 2025PodcastFin Climbed From 35% to 65% Resolution. Intercom Says the Models Only Did a Few PointsHost Nathan LabenzEoghan McCabe and Fergal Reid on production A/B tests, 99-cent outcome pricing, and why GPT-4 was already smart enough for most customer service.
31:22ENNo Priors: AI, Machine Learning, Tech, & Startups· Sep 18, 2025Podcast · 2 speakersDecagon Prices AI Support by the Conversation. The Market Is Wages.Host Sarah Guo, Elad GilJesse Zhang on six-figure contracts at zero ARR, 60–70% contact-center cuts, and a world where your agent calls the airline’s agent.
1:55:02ENCognitive Revolution "How AI Changes Everything"· Aug 30, 2025PodcastA hundred experiments a day, and the valley of death in materialsHost Nathan LabenzRadical AI’s co-founders tell Nathan Labenz how a closed loop of frontier models and a self-driving lab is meant to collapse a forty-year materials cycle into less than a decade.
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Sequoia Capital· Aug 26, 2025PodcastSix Years of Revenue, Then Four Times That in Eight Monthsn8n CEO Jan Oberhauser tells Sequoia how two bets — becoming an AI-agent builder, then deleting the leads metric — turned a workflow tool into a default orchestration layer.
42:12ENNo Priors: AI, Machine Learning, Tech, & Startups· Aug 21, 2025Podcast · 2 speakersHire the AI First: Andrew Ng on Agentic Workflows and the Scarcity of JudgmentHost Sarah Guo, Elad GilOn No Priors, Andrew Ng argues that agentic AI has made software cheap and fast, which moves the bottleneck to product judgment, error analysis, and the instinct to try an AI before adding headcount.
1:48:49ENCognitive Revolution "How AI Changes Everything"· Aug 16, 2025Podcast$500, 2,000 Steps, and a Vending Machine: Grok 4 Profited, Claude Called the FBIHost Nathan LabenzAndon Labs put frontier models in charge of simulated and real vending machines to see what breaks when nobody is in the loop.
37:37ENSequoia Capital· Jul 22, 2025PodcastA dozen people, 28 minutes, and one shared desktopThe OpenAI trio behind ChatGPT Agent explain how Deep Research and Operator became a virtual computer that can reason for half an hour and still ask you before it spends money.
41:13ENSequoia Capital· Jul 11, 2025PodcastFrom 49 Multiplications to 48: DeepMind’s AI Rewrites a Fifty-Year Math RecordPushmeet Kohli explains how AlphaEvolve couples Gemini with evaluators to invent algorithms, prove old conjectures, and change which scientific problems are even worth attempting.
1:25:32ENCognitive Revolution "How AI Changes Everything"· Jul 2, 2025Podcasto3 Invented a Voting Rule and Kept the Job: Four Weeks Inside the AI VillageHost Nathan LabenzAdam Binksmith on putting Claude, o3, and Gemini in a shared world for weeks—and why most people still imagine multi-agent life as one AI times four.
1:23:32ENCognitive Revolution "How AI Changes Everything"· Jun 28, 2025PodcastHTTP 402 Slept for Thirty Years. Coinbase Turned It Into a Payment Protocol for AI AgentsHost Nathan LabenzNemil Dalal, Coinbase's developer platform lead, explains x402, the open standard that lets agents pay for APIs with stablecoins instead of ads or credit cards.
38:48ENCognitive Revolution "How AI Changes Everything"· Jun 14, 2025PodcastTask Length Doubles Every Few Months. Nathan Labenz Still Wants Humans in ChargeHost Nathan LabenzAt Imagine AI Live, the Cognitive Revolution host maps structured AI agents against autonomous agentic systems—and tells businesses to keep final control.
41:25ENNo Priors: AI, Machine Learning, Tech, & Startups· Jun 12, 2025Podcast · 2 speakersBen Mann thinks superintelligence by 2028 is quite possibleHost Sarah Guo, Elad GilAnthropic's co-founder tells No Priors how Claude 4 unlocked hours of unattended agent work, why the lab built Claude Code, and what an economic Turing test would actually measure.
1:12:29ENCognitive Revolution "How AI Changes Everything"· Jun 4, 2025PodcastGoogle's AI Co-Scientist Solved a Phage Puzzle Humans Missed for YearsHost Nathan LabenzImperial College scientists José Penadés and Tiago Costa told the Podovirus podcast how a still-unreleased Google system recovered their unpublished answer: tailless capsids that pick up stray phage tails.
38:25ENSequoia Capital· May 27, 2025PodcastA thousand airplanes will never train an AI engineerFormer Airbus CTO Paul Eremenko explains why physical-world engineering still has no coding-AI moment, and how P-1 AI's agent Archie is supposed to get there anyway.
30:46ENNo Priors: AI, Machine Learning, Tech, & Startups· Apr 24, 2025Podcast · 2 speakersDeep Research Turned Web Browsing into a Trainable ProblemHost Sarah Guo, Elad GilOpenAI researcher Isa Fulford explains why a side project on read-only synthesis became an agent, when reinforcement fine-tuning is worth it, and why models will hack the search engine you gave them.
1:26:21ENCognitive Revolution "How AI Changes Everything"· Apr 10, 2025PodcastFor under $10, Google's AI independently recovered a lab result nobody had publishedHost Nathan LabenzVivek Natarajan and Anil Palepu tell Nathan Labenz how AMIE beats primary-care doctors on treatment plans, and how Co-Scientist matched Imperial College's unpublished bacterial-resistance mechanism.
2:14:59ENCognitive Revolution "How AI Changes Everything"· Mar 29, 2025PodcastAlways Bet on the Models: How Shortwave's Andrew Lee Shipped Tasklet as Agents All the Way DownHost Nathan LabenzThe Firebase co-founder argues that workflow software is already obsolete, that MCP is optional, and that the only durable advantage left for an AI startup is speed.
43:04ENSequoia Capital· Mar 25, 2025Podcast750 Million Excel Users, 30 Million Engineers: Wordware's Bet on Word ArtisansFilip Kozera tells Sequoia why English is the assembly language of LLMs, and why the people who win will be the ones who can encode taste into structured prompts.
32:46ENSequoia Capital· Feb 25, 2025PodcastDon't draw the flowchart: OpenAI's Deep Research team on training agents end to endIsa Fulford and Josh Tobin explain why Deep Research was trained with reinforcement learning on hard browsing tasks instead of a human-written graph of model calls.
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Unsupervised Learning: With Jacob Effron· Feb 19, 2025PodcastThe Cheaper Intelligence Gets, the More of It We'll BuyHost Jacob EffronAmazon AGI Lab head David Luan on what DeepSeek actually meant, why next-token prediction is not enough, and why agents are still stuck on reliability.
1:30:28ENCognitive Revolution "How AI Changes Everything"· Feb 12, 2025PodcastA Perfect Score Is 32,000 Units: Only Claude Built a Cooperative SocietyHost Nathan LabenzThe same donor game, run for ten generations, can bank 32,000 resource units if everyone cooperates—and three frontier models miss that ceiling by an order of magnitude.Load moreShowing 24 of 108