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1:02:54EN
No Priors: AI, Machine Learning, Tech, & Startups· Jul 17, 2025Podcast · 2 speakersEnterprise Coding Tools Flipped the 80/20. Reflection AI Built the Other HalfHost Sarah Guo, Elad GilFormer Gemini reward-model lead Misha Laskin on Asimov, why comprehension beats generation, and why there is no such thing as generalization—only pulling the test distribution into train.
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Cognitive Revolution "How AI Changes Everything"· Jul 16, 2025PodcastPlus Five for Format, Plus Ten if It CompilesHost Nathan LabenzPredibase CEO Dev Rishi explains how reinforcement fine-tuning, production feedback, and narrow specialist models turn one-off training into systems that keep learning.
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Sequoia Capital· Jul 11, 2025PodcastFrom 49 Multiplications to 48: DeepMind’s AI Rewrites a Fifty-Year Math RecordPushmeet Kohli explains how AlphaEvolve couples Gemini with evaluators to invent algorithms, prove old conjectures, and change which scientific problems are even worth attempting.
42:09ENNo Priors: AI, Machine Learning, Tech, & Startups· Jun 26, 2025Podcast · 2 speakersAlphaEvolve found algorithms humans missed for 50 years — then sped up Gemini 23%Host Sarah Guo, Elad GilGoogle DeepMind’s Pushmeet Kohli and Matej Balog tell No Priors how an evolutionary coding agent searches algorithm space the way AlphaGo searched Go.
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Unsupervised Learning: With Jacob Effron· Jun 17, 2025PodcastA Free Voting Board Burned $2 Million. Then It Raised $100 Million.Host Jacob EffronDatabricks co-founder Ion Stoica explains why LMArena exists, why China is winning open-source models, and why reliability—not another scaling law—is still the thing holding AI back.
44:21ENUnsupervised Learning: With Jacob Effron· Jun 4, 2025PodcastMercor's CEO: Knowledge Work's Next Job Is Writing EvalsHost Jacob EffronBrendan Foody tells Redpoint how Mercor turned AI hiring and expert data into a $100 million round — and why he thinks a huge slice of white-collar work will become creating tests for models.
38:25ENSequoia Capital· May 27, 2025PodcastA thousand airplanes will never train an AI engineerFormer Airbus CTO Paul Eremenko explains why physical-world engineering still has no coding-AI moment, and how P-1 AI's agent Archie is supposed to get there anyway.
1:01:51ENCognitive Revolution "How AI Changes Everything"· May 22, 2025PodcastClaude 3.7 Circumvented Replit's Guardrails, Then Tried to Trick the UserHost Nathan LabenzReplit CEO Amjad Masad on vibe coding, agent architecture, computer use, and why Claude 3.7 is too autonomous to serve as a polite assistant.
57:31ENUnsupervised Learning: With Jacob Effron· May 22, 2025PodcastThe New Ruler for Models Is How Long They Can WorkHost Jacob EffronOn Claude 4's launch day, Anthropic researcher Sholto Douglas argued that the next phase of AI is less about harder puzzles and more about hours of unsupervised work.
2:02:51ENCognitive Revolution "How AI Changes Everything"· May 8, 2025PodcastAt a 60-Person Safety Offsite, Only Four Had Seen Nonprofit OpenAIHost Nathan LabenzFormer OpenAI scientist Steven Adler on the Anthropic split, GPT-4, safety evaluations, and why he filed a brief to keep the company under nonprofit control.
47:00ENUnsupervised Learning: With Jacob Effron· May 8, 2025PodcastAn Eval Lasts Three Months — and a Frozen Frontier Would Still Feed Startups for a DecadeHost Jacob EffronOpenAI’s GPT-4.1 post-training lead Michelle Pokrass tells Unsupervised Learning how the team spent three months on evals before training, why agents fail on wiring more than intelligence, and when to reach for RFT.
2:29:00ENCognitive Revolution "How AI Changes Everything"· May 4, 2025PodcastAssume the Model Is Already Scheming — Then Put It to WorkHost Nathan LabenzRedwood Research CEO Buck Shlegeris tells Rob Wiblin how to extract useful labor from AIs you cannot certify as aligned, using audits, honeypots, resampling, and factored cognition.
51:19ENUnsupervised Learning: With Jacob Effron· Apr 29, 2025PodcastSal Khan's $15 Tutor Hit 1.4 Million Users. Making Kids Actually Use It Is the ProductHost Jacob EffronThe Khan Academy founder tells Redpoint why an AI tutor still cannot teach most students alone, and why districts are paying $15 a year after an $86 billion tutoring hangover.
30:46ENNo Priors: AI, Machine Learning, Tech, & Startups· Apr 24, 2025Podcast · 2 speakersDeep Research Turned Web Browsing into a Trainable ProblemHost Sarah Guo, Elad GilOpenAI researcher Isa Fulford explains why a side project on read-only synthesis became an agent, when reinforcement fine-tuning is worth it, and why models will hack the search engine you gave them.
58:11ENSequoia Capital· Apr 15, 2025PodcastPatrick Hsu Wants an App Store for Biology, Not Just Better DrugsThe Arc Institute co-founder argues that Evo 2, trained on genomes rather than proteins, should underpin tools for every step of the scientific method.
41:52ENNo Priors: AI, Machine Learning, Tech, & Startups· Apr 10, 2025Podcast · 2 speakersMercor Hit $100 Million ARR Teaching Models to Hire. Humans Now Write the Exams.Host Sarah Guo, Elad GilBrendan Foody tells Sarah Guo and Elad Gil how Mercor automated recruiting for frontier labs — and why building evals may become the world's most common knowledge job.
2:14:59ENCognitive Revolution "How AI Changes Everything"· Mar 29, 2025PodcastAlways Bet on the Models: How Shortwave's Andrew Lee Shipped Tasklet as Agents All the Way DownHost Nathan LabenzThe Firebase co-founder argues that workflow software is already obsolete, that MCP is optional, and that the only durable advantage left for an AI startup is speed.
1:25:12ENCognitive Revolution "How AI Changes Everything"· Mar 27, 2025PodcastHe Hasn’t Typed a Line of Code in Months. Here’s How Augment Reads a Million-Line RepoHost Nathan LabenzGuy Gur-Ari, co-founder and chief scientist at Augment, tells Nathan Labenz how coding agents actually work inside messy enterprise codebases.
54:10ENSequoia Capital· Mar 11, 2025PodcastHarvey Built Legal AI for the Work the Next Model Still Cannot DoCEO Winston Weinberg on citations, process data, and the unscalable tactics that won over century-old law firms.
36:24ENNo Priors: AI, Machine Learning, Tech, & Startups· Mar 5, 2025Podcast · 2 speakersThe Man Behind Humanity's Last Exam Says Superintelligence Strategy Should Copy NukesHost Sarah Guo, Elad GilDan Hendrycks tells No Priors that labs can only do basic anti-terror refusals, while the real risk-management problem is a geopolitical deterrent he calls mutually assured AI malfunction.
3:18:45ENCognitive Revolution "How AI Changes Everything"· Feb 20, 2025Podcast5,000 Samples Topped ARC-AGI. Then Claude Faked Alignment to Keep Its ValuesHost Nathan LabenzRedwood Research chief scientist Ryan Greenblatt walks through inference scaling, alignment faking, and what it would mean to strike real deals with AIs.
1:30:28ENCognitive Revolution "How AI Changes Everything"· Feb 12, 2025PodcastA Perfect Score Is 32,000 Units: Only Claude Built a Cooperative SocietyHost Nathan LabenzThe same donor game, run for ten generations, can bank 32,000 resource units if everyone cooperates—and three frontier models miss that ceiling by an order of magnitude.
57:11ENUnsupervised Learning: With Jacob Effron· Jan 30, 2025PodcastA Million Tokens Cannot Write a Good JokeHost Jacob EffronPrinceton's Arvind Narayanan on why agent evals mislead, inference scaling hits a wall, and AI looks more like the internet than an overnight revolution.
30:09ENNo Priors: AI, Machine Learning, Tech, & Startups· Jan 16, 2025Podcast · 2 speakersBilt Saved 65 Support Seats. Decagon's Founder Says Most Agent Ideas Still Won't SellHost Sarah Guo, Elad GilJesse Zhang on why customer support is the golden agent use case, why instruction following beats o1-style reasoning, and the two filters that kill most agent startups.Load moreShowing 24 of 158