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57:41EN
No Priors: AI, Machine Learning, Tech, & Startups· Feb 25, 2025Podcast · 2 speakersA Hundred Million Cells, Four People, Three Days: Biology's ImageNet MomentHost Sarah Guo, Elad GilVevo Therapeutics and the Arc Institute open-sourced Tahoe-100M and a 230-million-cell atlas in the same week — and argued that virtual cells, not just protein folders, are the next language model of biology.
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Cognitive Revolution "How AI Changes Everything"· Feb 9, 2025PodcastStackBlitz Almost Shut Down. Then Bolt Hit $20 Million ARR in Eight Weeks.Host Nathan LabenzEric Simons tells Nathan Labenz how a seven-year browser operating system, Claude Sonnet 3.5, and a text box replaced the local toolchain.
2:16:17ENCognitive Revolution "How AI Changes Everything"· Feb 5, 2025PodcastA 10B Model Trained Across Three Continents — and an H200 for $1.49 an HourHost Nathan LabenzPrime Intellect's founders lay out a four-step plan to turn spare global GPUs into collectively owned intelligence, and argue that reinforcement learning just made their job easier.
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Sequoia Capital· Jan 14, 2025PodcastIf Someone Builds a Better Spark Product, We Deserve to LoseIon Stoica on how Databricks turned academic open source into a data-and-AI company — and which problems he thinks will matter more tomorrow than today.
2:11:15ENCognitive Revolution "How AI Changes Everything"· Dec 25, 2024PodcastA 50% Chance of Extinction — and a $50 GPT-4 for EveryoneHost Nathan LabenzEmad Mostaque tells Nathan Labenz why he puts p(doom) at even odds, why a five-watt model changes the energy debate, and how the Intelligent Internet would fund universal basic AI with a Bitcoin-like token.
38:05ENNo Priors: AI, Machine Learning, Tech, & Startups· Dec 5, 2024Podcast · 2 speakersFrom Zero to $20M ARR in Two Months: Bolt's Moat Lives in the BrowserHost Sarah Guo, Elad GilStackBlitz CEO Eric Simons tells No Priors how a five-year WebContainers bet, an open-sourced prompt, and a community of non-coders turned Bolt.new into an overnight full-stack generator.
42:59ENNo Priors: AI, Machine Learning, Tech, & Startups· Aug 29, 2024Podcast · 2 speakersAWS Is a $100 Billion Cloud. Matt Garman Still Sees a 10x Migration AheadHost Sarah Guo, Elad GilAmazon Web Services’ new CEO tells No Priors why 85 percent of workloads are still on-prem, how Bedrock was built from three bets, and why startups remain the company’s growth engine.
1:40:13ENCognitive Revolution "How AI Changes Everything"· Aug 24, 2024PodcastIf I Were Governor, I Would Sign: California's Last Debate Over SB 1047Host Nathan LabenzThree guests return to unpack the rewritten frontier-AI bill as OpenAI opposes it, Anthropic calls it workable, and a final vote looms in Sacramento.
2:04:15ENCognitive Revolution "How AI Changes Everything"· Aug 14, 2024PodcastA parrot cannot paraphrase — and Claude cannot be talked into harmHost Nathan LabenzRobert Wright of the Nonzero podcast interviews Nathan Labenz on whether large language models understand anything, what Anthropic’s 10 million features actually show, and why open weights collide with U.S.–China policy.
1:56:03ENCognitive Revolution "How AI Changes Everything"· Jul 13, 2024PodcastHumans Near a Perfect Score. The Best AI Still Gets 39%Host Nathan LabenzZapier co-founder Mike Knoop and François Chollet put $1 million on ARC-AGI, a 2019 test of sample-efficient intelligence that language models still cannot crack under a one-cent-per-puzzle budget.
26:00ENNo Priors: AI, Machine Learning, Tech, & Startups· Jun 11, 2024Podcast · 2 speakersWhy a Zapier founder thinks AGI research has been stalled for four yearsHost Sarah Guo, Elad GilMike Knoop and François Chollet put more than a million dollars on beating ARC-AGI, the eval they say actually measures general intelligence.
1:23:10ENCognitive Revolution "How AI Changes Everything"· Jun 8, 2024PodcastThe night Flo Crivello slept five hours: GPT-4 never hit a wallHost Nathan LabenzThe Lindy AI founder walks Nathan Labenz through timelines, misuse, open-source risk, and why two longtime libertarians now want regulation.
31:04ENCognitive Revolution "How AI Changes Everything"· Jun 4, 2024PodcastThe Risk Is Not China Copying. It Is America Refusing to Use the ToolsHost Nathan LabenzAt the 2024 Hill & Valley Forum, Alex Wang, Jack Clark, and Andrew Ng tell Senator Cory Booker that Chinese labs are inventing, open-source models are already strong, and the Pentagon’s real AI failure is under-adoption.
46:20ENCognitive Revolution "How AI Changes Everything"· May 15, 2024PodcastOne Vector Made the Assistant Plot to Take Over the WorldHost Nathan LabenzNathan Labenz and Robert Wright pick apart AI doom, mechanistic interpretability, and why today's alignment tricks are not expected to work.
54:25ENCognitive Revolution "How AI Changes Everything"· May 9, 2024PodcastJail Only for Perjury: Scott Wiener Walks Through California's Frontier AI BillHost Nathan LabenzSB 1047 sets the same 10^26 FLOPs threshold as the Biden executive order, and the San Francisco senator wants testing without a licensing regime.
1:52:18ENCognitive Revolution "How AI Changes Everything"· May 6, 2024PodcastTwo Weeks, Thirty Compiles: How Adam Majmudar Wrote a GPU From ScratchHost Nathan LabenzA Cognitive Revolution walkthrough of TinyGPU, from SIMD kernels and memory latency to an open-source chip flow that runs on a laptop.
2:00:00ENCognitive Revolution "How AI Changes Everything"· May 4, 2024PodcastA 10^26 FLOP Training Run Would Put California Labs on the HookHost Nathan LabenzNathan Calvin, Dean Ball, and Steve Newman argue over SB 1047, the first U.S. statute aimed at frontier-model tail risk.
1:37:52ENCognitive Revolution "How AI Changes Everything"· Apr 10, 2024PodcastChina Has 17 Million Chatbot Users and No OpenAIHost Nathan LabenzA Beijing-based watcher walks through China's LLM players, products, regulation, and the delayed bill from the U.S. chip ban.
1:44:23ENCognitive Revolution "How AI Changes Everything"· Mar 16, 2024PodcastYou Can Split Your Vote by Issue — and Hand It to an AIHost Nathan LabenzTim Reutemann’s 2018 novel Liquid Reign sketches a 2051 democracy built on Swiss citizen initiatives, liquid delegation, and personal AIs you can mute.
39:03ENNo Priors: AI, Machine Learning, Tech, & Startups· Feb 29, 2024Podcast · 2 speakersMI300 Leads Inference by 2x: AMD's CTO on Winning Chip Competition Without a Walled GardenHost Sarah Guo, Elad GilWhen Mark Papermaster became AMD's CTO in fall 2011, nearly all of the company's revenue sat on PCs and gaming, Moore's Law was slowing, and everyone knew it needed a turnaround.
1:01:53ENCognitive Revolution "How AI Changes Everything"· Feb 13, 2024PodcastCompanion Apps Open Twice as Often as TikTok. a16z Only Funds Weird but WorkingHost Nathan Labenza16z consumer partners Anish Acharya and Justine Moore walk Nathan Labenz through their Abundance Agenda for AI-native consumer apps.
39:36ENNo Priors: AI, Machine Learning, Tech, & Startups· Dec 14, 2023Podcast · 2 speakersThe Most Underestimated AI Buyer Is the Shop on the CornerHost Sarah Guo, Elad GilFormer Square CEO Alyssa Henry tells No Priors that generative AI is unlocking work small merchants always needed and never paid anyone to do.
1:15:39ENCognitive Revolution "How AI Changes Everything"· Nov 29, 2023PodcastAfter 20 Years of Frontend, v0 Wrote Better Code Than Guillermo Rauch DidHost Nathan LabenzThe Vercel CEO tells Nathan Labenz why every product needs ghost text, why Software 2.0 will ossify the old stack, and why betting against open source is still the expensive mistake.
32:57ENNo Priors: AI, Machine Learning, Tech, & Startups· Nov 9, 2023Podcast · 2 speakersA 7-billion-parameter model on a MacBook: Mistral's CEO reruns the cost of AIHost Sarah Guo, Elad GilArthur Mensch tells No Priors why Chinchilla made small models valuable, why open-sourcing Mistral 7B is not a bioweapon risk, and why guardrails belong on the application.Load moreShowing 24 of 104