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37:39ENThe T3 Stack’s Tradeoffs, Explained by Its CreatorTheoA 2022 critique of the stack’s components, defaults and project fit.
3:00:21ENCut Off a Planarian's Head. The New Brain Still RemembersGuest Michael Levin · Host Lex FridmanMichael Levin argues that DNA only builds hardware, bioelectric networks store body plans, and frog skin cells can become robots that evolution never designed.
52:02ENTarek Mansour on Building Kalshi, Hiring Engineers and Operating Under ConstraintsGuest Tarek Mansour · Host Harry StebbingsKalshi’s founder discusses the origin of event contracts, recruitment, capital discipline and his 2022 vision for the market.
56:34ENKipp Bodnar on Marketing Channels, Brand and Building a CMO CareerGuest Kipp Bodnar · Host Harry StebbingsHubSpot’s marketing leader discusses focused distribution, customer-centered stories, attribution and the trade-offs of developing a broad leadership skill set.
2:21:28ENThe Seventh-Best Player in the World Is Still the SuckerGuest Daniel Negreanu · Host Lex FridmanDaniel Negreanu talks with Lex Fridman about tells, solvers, variance, and why finding the right table beats being ranked seventh.
51:22ENPaul Davison on Clubhouse, Live Conversation and Building CommunityGuest Paul Davison · Host Harry StebbingsThe Clubhouse co-founder discusses rapid growth, retention, the limits of live content and his plans for smaller social groups.
2:21:55ENWill Sasso Respects Stand-Up Too Much to Do ItGuest Will Sasso · Host Lex FridmanThe MADtv veteran tells Lex Fridman why he never became a stand-up, why impressions work from the outside in, and why he thinks AI is running the same illusion.
59:19ENJulio Vasconcellos on Scaling Peixe Urbano, Investment Focus and Latin AmericaGuest Julio Vasconcellos · Host Harry StebbingsThe Atlantico founder discusses rapid expansion, difficult founder feedback and his historical view of technology adoption and funding in Latin America.
1:08:51ENDavid Lieb on Bump, Google Photos and Product JudgmentGuest David Lieb · Host Harry StebbingsThe former Google Photos leader discusses founder ownership, customer discovery, retention, product reviews and the limits of intuition.
2:36:21ENA Smile Is Not Happiness: Rana el Kaliouby on Emotion AI and the Empathy CrisisGuest Rana el Kaliouby · Host Lex FridmanThe Affectiva founder and Smart Eye deputy CEO talks with Lex Fridman about teaching machines to read faces, sensing drivers inside the cabin, and why she is proudest of the people her company grew.
1:36:11EN2029 Passes the Turing Test. 2045 Is Still the SingularityGuest Ray Kurzweil · Host Lex FridmanRay Kurzweil tells Lex Fridman why his dates have not moved, how to invent in the present tense, and why the replica of his father answered the meaning of life with one word: love.
44:50ENSebastian Kanovich on Building dLocal from Uruguay and Scaling Across Emerging MarketsGuest Sebastian Kanovich · Host Harry StebbingsThe dLocal CEO discusses customer-led expansion, bootstrapping and the challenge of preserving a small-team culture after an IPO.
2:15:36ENThe War That Invented the Modern American CitizenGuest Christopher Capozzola · Host Lex FridmanMIT historian Christopher Capozzola tells Lex Fridman how World War I rewired American citizenship, surveillance, and the war machine — and why those patterns still shape elections, platforms, and foreign policy.
48:43ENEleanor Dorfman on Building Sales Teams, Playbooks and Customer-Centered ReviewsGuest Eleanor Dorfman · Host Harry StebbingsThe Retool sales leader explains how founders can learn from early customers, hire for ambiguity and build repeatable sales practices.
1:08:45ENWill Quist on Venture Capital, Investment Risk and Going Beyond ConsensusGuest Will Quist · Host Harry StebbingsThe Slow Ventures partner distinguishes classic venture from growth investing and explains his framework for evaluating companies and building a portfolio.
1:00:28ENElla Ehrlich on Modernizing a Critical Trading SystemYaron Minsky, Ella Ehrlich · Jane StreetJane Street’s Gord team rebuilt parts of a legacy data pipeline while preserving availability, and Ehrlich describes the recruiting programs she helped develop.
2:35:37ENYou Play Better Chess When You Stop Caring About the NumberGuest Botez Sisters · Host Lex FridmanAlexandra and Andrea Botez talk with Lex Fridman about ratings, streaming personas, depression, and why obsession with a board game can swallow a life.
3:43:01ENPut Hydrogen and CO2 in a Tube. Thermodynamics Wants Cells. Nothing Happens.Guest Nick Lane · Host Lex FridmanBiochemist Nick Lane talks Lex Fridman through hydrothermal vents, mitochondria, sex, consciousness, and why bacteria should be common while civilizations are not.
1:05:21ENMichael Mignano on Anchor, Venture Investing and the Future of Social MediaGuest Michael Mignano · Host Harry StebbingsThe Anchor co-founder discusses joining Lightspeed, the limits of startup hype and why recommendation media may create room for new social products.
3:11:01ENWhere Do You Go for Wisdom? John Vervaeke on the Meaning CrisisGuest John Vervaeke · Host Lex FridmanA University of Toronto cognitive scientist argues that meaning is a real relationship between self and world, and that modern life has lost the practices that used to repair it.
49:35ENAnnie Pearl on Product Focus, Enterprise Expansion and Hiring Product LeadersGuest Annie Pearl · Host Harry StebbingsThe Calendly product leader explains how to time a second product, align self-service and enterprise work, and evaluate product candidates.
47:12ENPutin’s invasion is a supreme crime, Chomsky says — and so was America’s in IraqGuest Noam Chomsky · Host Lex FridmanIn a short remote interview, Noam Chomsky applies one standard to NATO expansion, Western propaganda, and a US-China war he thinks organized human life would not survive.
59:48ENLogan Bartlett on Growth Investing, Valuations and Board Responsibilities in 2022Guest Logan Bartlett · Host Harry StebbingsThe Redpoint investor discusses the stalled growth market, private-company marks, follow-on decisions and how boards work with founders.
2:31:52ENMagnus Carlsen would rather trust the numbers than the fairy taleGuest Magnus Carlsen · Host Lex FridmanThe highest-rated chess player in history tells Lex Fridman how he defines greatness, why he stopped defending the world title, and what a two-dimensional board in his head actually looks like.
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