Results
71 articlesSort
3:21:29ENWhen something in the mind breaks, you see what it was forGuest Karl Deisseroth · Host Lex FridmanStanford psychiatrist Karl Deisseroth talks with Lex Fridman about depression, schizophrenia, optogenetics, and why you can treat one symptom without a theory of everything.
2:10:56ENGod Cannot Be Expressed, Only AddressedGuest David Wolpe · Host Lex FridmanRabbi David Wolpe talks with Lex Fridman about Judaism’s many pictures of God, friendship with atheists, and why a living tradition can argue with its own book.
4:05:51ENLife is the universe developing a memoryGuest Lee Cronin · Host Lex FridmanChemist Lee Cronin tells Lex Fridman why life looks inevitable, how assembly theory could detect it on any world, and why silicon may never hold enough states for consciousness.
2:46:31ENThe Official Scientific Worldview Is Incompatible With ConsciousnessGuest Philip Goff · Host Lex FridmanDurham philosopher Philip Goff tells Lex Fridman why panpsychism — the view that consciousness is fundamental and ubiquitous — is the least-bad theory of mind.
2:45:10ENA Teenager Learns to Drive in Twenty Hours. A Car Still Cannot.Guest Yann Lecun · Host Lex FridmanYann LeCun tells Lex Fridman why self-supervised world models are the missing dark matter of intelligence, and why machines are not even at the level of a house cat.
3:38:43ENConsciousness Is a Step Down From IntelligenceGuest Stephen Wolfram · Host Lex FridmanStephen Wolfram tells Lex Fridman how simple programs, a discrete fabric of space, and a computationally bounded observer together explain complexity, physics, and why the universe exists.
1:45:45ENA Blink of Ordered Particles: Brian Greene on Entropy, Meaning, and DeathGuest Brian Greene · Host Lex FridmanThe Columbia physicist talks with Lex Fridman about heat death, consciousness, string theory, the Big Bang, aliens, Mars, and the kind of freedom that survives without free will.
1:26:20ENRZA: You Can Be Wisdom. You Cannot Raise the Dead.Guest RZA · Host Lex FridmanThe Wu-Tang Clan architect talks with Lex Fridman about his mother's death, kung fu, chess, Allah, and why confusion is a gift.
3:12:21ENThe Ape's Brain Runs a Dream: Joscha Bach on Consciousness, Freedom, and MeaningGuest Joscha Bach · Host Lex FridmanA long conversation about the self as a control model, the dream world generated by the brain, free will, language models, evil, love, and how to live without a fixed self.
1:52:28ENIf You Die Before You Die: Brian Muraresku's Secret History of PsychedelicsGuest Brian Muraresku · Host Lex FridmanThe author of The Immortality Key tells Lex Fridman why ancient wine was a drug, why Eleusis mattered more than democracy, and why mystics keep running toward death.
2:48:18ENHumans are the only species that skip sleep on purposeGuest Matt Walker · Host Lex FridmanBerkeley sleep scientist Matt Walker talks with Lex Fridman about why we sleep, what caffeine and dreams actually do, and whether passion can justify the health cost of staying up.
2:36:06ENThe Experience Is Not in the Pill. Rick Doblin Spent Decades Proving the Context Is.Guest Rick Doblin · Host Lex FridmanThe MAPS founder walks Lex Fridman from Huxley's reducing valve to a Phase 3 MDMA trial for PTSD, arguing that legality, safety, and culture matter more than new molecules.
1:59:28ENSara Walker says “what is life?” is the wrong questionGuest Sara Walker · Host Lex FridmanThe astrobiologist and theoretical physicist tells Lex Fridman that origin-of-life science is stuck on molecules, and that causation, assembly, and planetary-scale information are closer to the real problem.
2:22:20ENThe closer quarks get, the weaker they pullGuest Frank Wilczek · Host Lex FridmanNobel physicist Frank Wilczek talks with Lex Fridman about asymptotic freedom, beauty, dark matter, consciousness, and whether a theory of everything would even help.
2:58:38ENSleep runs on two clocks — and worrying about it can be worse than a short nightGuest Andrew Huberman · Host Lex FridmanStanford neuroscientist Andrew Huberman tells Lex Fridman how adenosine and body temperature decide when you crash, why dreams work like overnight therapy, and what the chemistry of effort has to do with not quitting.
2:39:15ENCraftsmanship, Graphs and Consciousness: Jim Keller on Building Computers That ThinkGuest Jim Keller · Host Lex FridmanLegendary chip architect Jim Keller talks with Lex Fridman about design philosophy, the future of AI hardware, the human mind and how to live well.
3:01:27ENA Belief Does Not Have to Be True to Remake the WorldGuest Diana Walsh Pasulka · Host Lex FridmanReligious-studies scholar Diana Walsh Pasulka tells Lex Fridman how Catholic limbo, Nietzsche, Silicon Valley “downloads,” and a desert monolith all describe the same machinery of belief and technology.
3:39:01ENMatthew Johnson on loosening the priors that run a human lifeGuest Matthew Johnson · Host Lex FridmanThe Johns Hopkins psychiatrist walks Lex Fridman through receptors, addiction, DMT entities, a 15-person smoking trial, and why psychedelics have taught us almost nothing about the hard problem of consciousness.
2:14:55ENHis Wife Calls Him the RadioGuest Manolis Kellis · Host Lex FridmanMIT computational biologist Manolis Kellis spends the first forty minutes of his fourth Lex Fridman conversation on the songs that formed him, then turns to 42, dinosaurs, and why hunting for meaning matters more than finding it.
2:20:31ENThe Most Romantic Gift Lisa Feldman Barrett Ever Got Was a Six-Way PlugGuest Lisa Feldman Barrett · Host Lex FridmanOn her second Lex Fridman Podcast, the neuroscientist traces how she fell in love over a 1992 bulletin board, why brains evolved to hunt rather than to think, and how a body budget can change a mood.
2:35:30ENOn a Perfectly Flat Floor, Heights Still WorkGuest Andrew Huberman · Host Lex FridmanStanford neuroscientist Andrew Huberman talks with Lex Fridman about fear circuits, matching inner arousal to outer demand, and why the first minutes after sleep should not belong to someone else's timeline.
1:56:31ENA Blank Wall Is Not More Conscious Than a PersonGuest Scott Aaronson · Host Lex FridmanScott Aaronson walks Lex Fridman through integrated information theory, Penrose’s uncomputable mind, GPT-3, P versus NP, and why silent support for open discourse has to get louder.
2:23:38ENThe Brain That Never Touches the WorldGuest Lisa Feldman Barrett · Host Lex FridmanNeuroscientist Lisa Feldman Barrett tells Lex Fridman why your skull is a dark box, why emotions are constructed like money, and why empathy is a metabolic bill.
1:41:24ENA child can lose half a brain. The rest will rewire around the jobGuest David Eagleman · Host Lex FridmanNeuroscientist David Eagleman tells Lex Fridman why the human brain is not hardware running software, but a livewired system that never stops physically reshaping itself.
Load moreShowing 24 of 71









